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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

N-sulfanilylbenzamide
Synonym for sulfabenzamide ... An antimicrobial of the sulfonamide group. ... Synonym: N-sulfanilylbenzamide. ... (05 Mar 2000) ...

N-sulfoglucosamine-3-sulfatase
<enzyme> Acts on n-acetylglucosamine-3-sulfate and n-sulfoglucosamine-3-sulfate ... Registry number: EC 3.1.6.15 ... Synonym: n-substituted glucosamine 3-o-sulphatase ... (26 Jun 1999) ...

N-terminus
Synonym for amino-terminal ... <biochemistry> The end of a protein or polypeptide chain with the unattached amino group or the aminoacyl residue containing it. ... Each amino acid in the chain has an amino group on one side, which is attached to the carboxyl group (COOH group) of the previous amino acid, and a carboxyl group on the other side ( …

n-tetracosanoic acid
Synonym for lignoceric acid ... CH3(CH2)22COOH;an acid present in one type of sphingolipid and in small amounts in triacylglycerols. ... Synonym: n-tetracosanoic acid. ... (05 Mar 2000) ...

N.BstSE nickase
<enzyme> Site-specific endodeoxyribonuclease from b. Stearothermophilus se-589 that cleaves only one chain of double-stranded DNA; acts at 5'-gagtcnnn/nn-3' ... Registry number: EC 3.1.21.- ... Synonym: bacillus stearothermophilus site-specific nickase ... (26 Jun 1999) ...

n0
<abbreviation> Loschmidt's number. ... (05 Mar 2000) ...

N1-acetylsulfanilamide
An antibacterial sulfa drug used topically and in the eye. ... (05 Mar 2000) ...

N10-formyltetrahydrofolate
A formyl derivative of tetrahydrofolate that serves as a one-carbon source in metabolism. ... (05 Mar 2000) ...

N4-acetylsulfanilamide
An intermediate in the synthesis of sulfanilamide; formed in animal bodies by acetylation of sulfanilamide. ... Synonym: p-sulfamylacetanilide. ... (05 Mar 2000) ...

N5-methyltetrahydrofolate
An active one-carbon derivative of tetrahydrofolate that participates in the S-methylation of l-homocysteine. ... (05 Mar 2000) ...

N5,N10-methenyltetrahydrofolate
A one-carbon derivative of tetrahydrofolate; used in purine biosynthesis. ... N5,N10-methylenetetrahydrofolate reductase, an enzyme that converts N5,N10-m ethylenetetrahydrofolate to N5,N10-methyl enyltetrahydrofolate using NADP+; a deficiency of this enzyme results in an accumulation of l-homocysteine and severe neurological disturbances. ... (05 Ma …

N5,N10-methenyltetrahydrofolic acid
Synonym for anhydroleucovorin ... An intermediate formed in the folic acid-catalyzed glycine-serine interconversion. ... Synonym: N5,N10-methenyltetrahydrofolic acid. ... (05 Mar 2000) ...

N6-acetyl-beta-lysine transaminase
<enzyme> Involved in oxidative catabolism of lysine by candida maltosa; forms 2-keto-6-acetamidocaproate ... Registry number: EC 2.6.1.65 ... Synonym: n6-acetyllysine transaminase, acl-at, n6-acetyllysine 2-oxoglutarate aminotransferase ... (26 Jun 1999) ...

na
The chemical symbol for sodium. From natrium, a synonym for sodium. Sodium chloride (ordinary salt) is nacl. ... (12 Dec 1998) ...

nabilone
(&plusmn;)-3-(1,1-Dimethylheptyl-6-6ab,7,8,10,10aa-hexahydro-1-hydroxy-6,6-dimethyl-9H-dibenzo[b,d ]pyran-9-one;a synthetic cannabinoid used in the treatment of nausea and vomiting associated with cancer chemotherapy. ... (05 Mar 2000) ...

Naboth
Martin, German anatomist and physician, 1675-1721. ... See: nabothian cyst, follicle. ... (05 Mar 2000) ...

nabothian cyst
<radiology> Chronic cervicitis most likely to be inflammatory stenosis of cervical glands most likely to be retention most likely to be cyst Differential diagnosis: cystic mass of cervix, ectopic pregnancy, adenomyosis ... (12 Dec 1998) ...

nabothian follicle
Synonym for nabothian cyst ... <radiology> Chronic cervicitis most likely to be inflammatory stenosis of cervical glands most likely to be retention most likely to be cyst Differential diagnosis: cystic mass of cervix, ectopic pregnancy, adenomyosis ... (12 Dec 1998) ...

nac
A naturally occurring substance that is metabolised into the amino acid cysteine. Cysteine is one of the three components of the major cellular antioxidant glutathione (see), and people with HIV have decreased levels of this compound. Clinical studies of oral and intravenously administered NAC are evaluating its usefulness in decreasing HIV activit …

nacreous
Consisting of, or resembling nacre, pearly, lustrous, like mother-of-pearl; descriptive term for bacterial colonies. ... Origin: Fr. Nacre, mother-of-pearl ... (21 Jun 2000) ...

nacreous ichthyosis
A variant of ichthyosis characterised by dry pearly scales. ... (05 Mar 2000) ...

NAD
<enzyme> Coenzymes that act as electron and hydrogen carriers in some oxidation-reduction reactions. ... (09 Oct 1997) ...

NAD synthetase
<enzyme> Consider also EC 6.3.5.1 ... Registry number: EC 6.3.1.5 ... Synonym: nad synthase ... (26 Jun 1999) ...

NAD transferase
<enzyme> Catalyses phosphorylation of host bacterial proteins ... Registry number: EC 2.7.7.- ... (26 Jun 1999) ...

NAD(P)-reducing nickel hydrogenase
<enzyme> From cyanobacterium, synechocystis; genbank x97610 ... Registry number: EC 1.12.1.- ... (26 Jun 1999) ...

NAD(P)+ nucleosidase
<enzyme> An enzyme hydrolyzing NAD(P)+ to release free nicotinamide and adenosinediphosphoribose(phosphate). ... (05 Mar 2000) ...

NAD(p)h dehydrogenase (quinone)
<enzyme> A flavoprotein that reversibly catalyses the oxidation of NADH or NADPH by various quinones and oxidation-reduction dyes. Since the enzyme is a part of the mitochondrial respiratory chain, defects or deficiencies of this enzyme are an important cause of neurological diseases such as parkinsonism. It may have a protective effect again …

NAD(P)H-adrenaline oxidase
<enzyme> Forms adrenochrome ... Registry number: EC 1.6.- ... (26 Jun 1999) ...

NAD+
<abbreviation> Nicotinamide adenine dinucleotide (oxidised form). ... (05 Mar 2000) ...

NAD+ ADP-ribosyltransferase
<enzyme> An enzyme isolated from the nuclei of a variety of cells. It catalyses the incorporation of ADP-ribose groups of NAD+ into a homopolymer of repeating ADP-ribose units. ... Chemical name: NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase ... Registry number: EC 2.4.2.30 ... (12 Dec 1998) ...

NAD+ nucleosidase
<enzyme> An enzyme that catalyses the hydrolysis of NAD to nicotinamide and adpribose. ... Chemical name: NAD+ glycohydrolase ... Registry number: EC 3.2.2.5 ... (12 Dec 1998) ...

NAD+ pyrophosphorylase
<enzyme> An enzyme that participates in the synthesis of NAD+; it reacts nicotinamide mononucleotide with ATP to produce NAD+ and pyrophosphate; it will also act on nicotinate mononucleotide. ... (05 Mar 2000) ...

NAD+ synthetase
<enzyme> An enzyme that catalyses the reaction of ATP, l-glutamine, and nicotinate adenine dinucleotide to form NAD+, ADP, and l-glutamate. ... (05 Mar 2000) ...

NADase
nAD+ nucleosidase ...

NADH
<abbreviation> Nicotinamide adenine dinucleotide (reduced form). ... (05 Mar 2000) ...

NADH dehydrogenase
<enzyme> A flavoprotein containing iron. Cytochrome c may act as receptor. The enzyme reversibly catalyses the oxidation of NADH to NAD and reduced acceptor. ... An inherited deficiency of this complex results in overwhelming acidosis. ... Synonym: cytochrome c reductase. ... Chemical name: NADH:(acceptor) oxidoreductase ... Registry number: EC 1 …

NADH kinase
<enzyme> From saccharomyces cerevisiae; phosphorylate diphosphopyridine nucleotides; found exclusively in the mitochondria ... Registry number: EC 2.7.1.86 ... (26 Jun 1999) ...

NADH sennidin reductase
<enzyme> Reduces the dianthrones senniden or sennoside to rheinanthrone or 8-glucosylrheinanthrone respectively ... Registry number: EC 1.- ... Synonym: sennoside reductase ... (26 Jun 1999) ...

NADH tetrazolium reductase
<enzyme> Catalyses the reduction of tetrazolium compounds in the presence of NADH. ... Registry number: EC 1.6.- ... (12 Dec 1998) ...

NADH-cytochrome P-450 reductase
<enzyme> A component of the cytochrome p-450sca monoxygenase system ... Registry number: EC 1.6.2.- ... (26 Jun 1999) ...

NADH-Fe(III)EDTA oxidoreductase
<enzyme> From cryptococcus albidus; catalyses the formation of nad+ and fe(ii)edta from NADH and fe(iii)edta; forms ethylene from 2-oxo-4-methylthiobutyric acid ... Registry number: EC 1.6.99.- ... (26 Jun 1999) ...

NADH-hydroxylamine reductase
<enzyme> An enzyme catalyzing the reaction of hydroxylamine and NADH to form ammonia, NAD+, and water; used in a number of clinical assays. ... (05 Mar 2000) ...

NADH-hypothiocyanite oxidoreductase
<enzyme> Catalyses reduction of hypothiocyanite to thiocyanate; isolated from streptococcus sanguis ... Registry number: EC 1.6.99.- ... Synonym: nhor enzyme ... (26 Jun 1999) ...

NADH-methyl viologen reductase
<enzyme> Fad-protein from rhodospirillum rubrum which also reduces methylene blue and 2,6-dichlorophenol-indophenol ... Registry number: EC 1.6.- ... (26 Jun 1999) ...

NADH-vandate oxidoreductase
<enzyme> Catalyses conversion of vanadate to vanadyl in the presence of NADH but not NADPH ... Registry number: EC 1.16.- ... Synonym: NADH-v oxidoreductase ... (26 Jun 1999) ...

NADH, NADPH oxidoreductases
<enzyme> A group of oxidoreductases that act on NADH or NADPH. In general, enzymes using NADH or NADPH to reduce a substrate are classified according to the reverse reaction, in which NAD+ or NADP+ is formally regarded as an acceptor. This subclass includes only those enzymes in which some other redox carrier is the acceptor. ... Registry numb …

NADH2 oxidase
<enzyme> Chemical name: reduced nicotinamide adenine dinucleotide oxidase ... Registry number: EC 1.6.- ... Synonym: NADH oxidase ... (26 Jun 1999) ...

Nadi reaction
Synonym for peroxidase reaction ... Formation of indophenol blue by the action of an oxidizing enzyme present in certain cells and tissues when they are treated with a solution of alpha-naphthol and dimethylparaphenylenediamine; by this method, cells of the myelocyte series, which give a positive reaction, may be distinguished from those of the lymp …

nadide
3-Carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide;a nicotinamide adenine dinucleotide compound used as an antagonist to alcohol and narcotics. ... (05 Mar 2000) ...

nadir
The lowest point, point of greatest adversity or despair. ... (18 Nov 1997) ...

nadolol
<chemical> 5(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-1,2,3,4-tetrahydro-2,3-naphthaenediol. A non-selective beta-adrenergic antagonist with a long half-life, used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension. Nadolol is also used for migraine and for tremor. ... Pharmacological action: adrenergic bet …

NADP
<chemical> Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (nmn) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidised (NADP+) and reduced (NADPH). ... Chemical name: Adenosine …

NADP phosphatase
<enzyme> Forms nad+ by hydrolysis of 3'-phosphate ... Registry number: EC 3.1.3.- ... Synonym: nadp+ phosphatase ... (26 Jun 1999) ...

NADP transhydrogenase
<enzyme> An enzyme present in the mitochondrial membrane of animals and in microorganisms. In the presence of energy (ATP) it catalyses reversibly the reduction of NAD by NADPH to yield NADP and NADH. This reaction permits the utilization of the reducing properties of NADPH by the respiratory chain and in the reverse direction it allows the r …

NADP-dependent flavonol reductase
<enzyme> Isolated from maise ... Registry number: EC 1.1.1.- ... Synonym: a1 gene product ... (26 Jun 1999) ...

NADP-reducing hydrogenase
<enzyme> Operon from desulfovibrio contains 4 genes: hnda, hndb, hndc and hndd; does not reduce nad; genbank u07229 ... Registry number: EC 1.12.1.- ... Synonym: hnd gene product, hndabcd gene product ... (26 Jun 1999) ...

NADP+
<abbreviation> Nicotinamide adenine dinucleotide phosphate (oxidised form). ... (05 Mar 2000) ...

NADPH
<abbreviation> Nicotinamide adenine dinucleotide phosphate (reduced form). ... (05 Mar 2000) ...

NADPH dehydrogenase
<enzyme> A flavoprotein that reversibly oxidises NADPH to NADP and a reduced acceptor. ... Chemical name: NADPH:(acceptor) oxidoreductase ... Registry number: EC 1.6.99.1 ... (12 Dec 1998) ...

NADPH dehydrogenase (quinone)
A flavoprotein similar to NADH dehydrogenase (quinone), but oxidizing NADPH. ... Synonym: DT-diaphorase, menadione reductase, phylloquinone reductase, quinone reductase. ... (05 Mar 2000) ...

NADPH diaphorase
Synonym for NADPH dehydrogenase ... <enzyme> A flavoprotein that reversibly oxidises NADPH to NADP and a reduced acceptor. ... Chemical name: NADPH:(acceptor) oxidoreductase ... Registry number: EC 1.6.99.1 ... (12 Dec 1998) ...

NADPH oxidase
<enzyme> A plasma membrane-associated enzyme complex that catalyses the univalent reduction of oxygen using NADPH as an electron donor. The superoxide anion formed acts as an oxidant in the phagocyte microbicidal system, proceeding through a series of electron transfer reactions that form the respiratory burst. Various genetic defects in the …

NADPH-cytochrome c2 reductase
<enzyme> An enzyme catalyzing the reduction of 2 ferricytochrome c2 to 2 ferrocytochrome c2 at the expense of NADPH. ... Synonym: cytochrome c2 reductase. ... (05 Mar 2000) ...

NADPH-ferrihemoprotein reductase
<enzyme> A flavoprotein that catalyses the reduction of haem-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. Its physiological acceptor is probably cytochrome p-450. ... Chemical name: NADPH:ferrihemoprotein oxidoreductase ... Registry number: EC 1.6.2.4 ... (12 Dec 1998) ...

NADPH-tetrazolium reductase
<enzyme> Reported to possess activity identical with NADPH cytochrome c reductase EC 1.6.2.4 ... Registry number: EC 1.6.2.- ... Synonym: NADPH-neotetrazolium reductase, NADPH-nbt reductase ... (26 Jun 1999) ...

nadroparin
<chemical> A heparin fraction with a mean molecular weight of 4500 daltons. It is isolated from porcine mucosal heparin and used as an antithrombotic agent. ... Pharmacological action: anticoagulant, fibrinolytic agent. ... (12 Dec 1998) ...

Naegeli syndrome
<syndrome> Reticular skin pigmentation, diminished sweating, hypodontia, and hyperkeratosis of the palms and soles; may be confused with incontinentia pigmenti but is as common in males as in females; autosomal dominant inheritance. ... Synonym: Franceschetti-Jadassohn syndrome. ... (05 Mar 2000) ...

Naegeli type of monocytic leukaemia
Synonym for myelomonocytic leukaemia ... A variant of granulocytic leukaemia with monocytosis in the peripheral blood. ... Synonym: Naegeli type of monocytic leukaemia. ... (05 Mar 2000) ...

Naegeli, Oskar
<person> Swiss physician, 1885-1959. ... See: Naegeli syndrome. ... (05 Mar 2000) ...

Naegeli, Otto
<person> Swiss physician, 1871-1938. ... See: Naegeli type of monocytic leukaemia. ... (05 Mar 2000) ...

naegleria
A free-living soil amoeba pathogenic to humans and animals. It occurs also in water and sewage. The most commonly found species in man is naegleri fowleri which is the pathogen for primary amebic meningoencephalitis in primates. ... (12 Dec 1998) ...

naegleria fowleri
A species of parasitic protozoa having both an ameboid and flagellate stage in its life cycle. Infection with this pathogen produces primary amebic meningoencephalitis. ... (12 Dec 1998) ...

Naegleria gruberi
<protozoa> A normally amoeboid protozoan found in the soil. When it is flooded with water or a solution of low ionic strength it transforms into a swimming form with two flagella. ... (13 Nov 1997) ...

naevus
<dermatology, tumour> Tumour like but nonneoplastic hamartoma of skin. A vascular naevus is a localised capillary rich area of the skin (strawberry birthmark, sometimes the much more extensive port wine stain). ... A mole benign melanoma) is a pigmented naevus, a cluster of melanocytes containing melanin. ... (13 Nov 1997) ...

NAF
<abbreviation> Neutrophil activating factor. ... (05 Mar 2000) ...

nafarelin
<chemical> 6-(3-(2-naphthalenyl)-d-alanine)luteinizing hormone-releasing factor (pig). A gonadorelin analog agonist. It has been used in the treatment of central precocious puberty and endometriosis. ... Pharmacological action: hormones, synthetic. ... Chemical name: Luteinizing hormone-releasing factor (pig), 6-(3-(2-naphthalenyl)-D-alanine)-< …

nafcillin
<chemical> A semi-synthetic antibiotic related to penicillin. ... Pharmacological action: penicillins. ... Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- ... (12 Dec 1998) ...

nafenopin
<chemical> A peroxisome proliferator that is used experimentally to promote liver tumours. It has been used as an antihyperproteinaemic agent. ... Pharmacological action: antilipaemic agents, carcinogens. ... Chemical name: Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)- ... (12 Dec 1998) ...

Naffziger
Howard C., U.S. Surgeon, 1884-1961. ... See: Naffziger operation, Naffziger syndrome. ... (05 Mar 2000) ...

Naffziger operation
Orbital decompression for severe malignant exophthalmos by removal of the lateral and superior orbital walls. ... (05 Mar 2000) ...

Naffziger syndrome
Scalenus-anticus syndrome ...

nafoxidine
<chemical> 1-(2-(4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)ethyl)pyrrolidine. An oestrogen antagonist that has been used in the treatment of breast cancer. ... Pharmacological action: antineoplastic agent, hormonal, oestrogen antagonists. ... Chemical name: Pyrrolidine, 1-(2-(4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy)e …

nafronyl
<chemical> 2-(diethylamino)ethyl tetrahydro-alpha-(1-naphthylmethyl)-2-furanpropionate oxalate. A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enchance cellular oxidative capacity and to be a spasmolytic. It may also be an antagonist at 5ht-2 serotonin receptors. ... Pharmacological action: parasy …

nafronyl oxalate
2-(Diethylamino)ethyl tetrahydro-alpha-(1-naphthylmethyl)-2-furanpropionate oxalate;a vasodilator drug. ... (05 Mar 2000) ...

naftifine hydrochloride
(E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride;a broad spectrum antifungal agent used in the topical treatment of tinea infections. ... (05 Mar 2000) ...

NAG
<abbreviation> N-acetylglutamate. ... (05 Mar 2000) ...

nagana
An acute or chronic disease of cattle, dogs, pigs, horses, sheep, and goats in sub-Saharan Africa; marked by fever, anaemia, and cachexia, varying in severity with the parasite and the host. A collective term for diseases caused by the protozoan parasites Trypanosoma brucei brucei, T. Congolense, and T. Vivax. ... (05 Mar 2000) ...

nagarse
<enzyme> Broad specifity protease from bacteria. ... (18 Nov 1997) ...

Nagel
Willibald, A., German ophthalmologist and physiologist, 1870-1911. ... See: Nagel's test. ... (05 Mar 2000) ...

Nagel's test
A test for colour vision in which the observer determines the relative amounts of red and green necessary to match spectral yellow; an instrument called Nagel's anomaloscope is used. ... (05 Mar 2000) ...

Nagele
Franz K., German obstetrician, 1777-1851. ... See: Nagele obliquity, Nagele's pelvis, Nagele's rule. ... (05 Mar 2000) ...

Nagele obliquity
Inclination of the foetal head in cases of flat pelvis, so that the biparietal diameter is oblique in relation to the plane of the pelvic brim, the anterior parietal bone presenting to the parturient canal. ... Synonym: anterior asynclitism. ... (05 Mar 2000) ...

Nagele's pelvis
An obliquely contracted or unilateral synostotic pelvis, marked by arrest of development of one lateral half of the sacrum, usually ankylosis of the sacroiliac joint on that side, rotation of the sacrum toward the same side, and deviation of the symphysis pubis to the opposite side. ... (05 Mar 2000) ...

Nagele's rule
Means of estimating date of delivery by counting back three months from the first day of the last menstrual period and adding seven days. ... (05 Mar 2000) ...

Nageli
Karl W. Von, Swiss botanist, 1817-1891. ... See: micelle. ... (05 Mar 2000) ...

Nageotte cells
Cell's found in the cerebrospinal fluid, one or two per cubic millimeter in health, but in greater numbers in various diseases. ... (05 Mar 2000) ...

Nageotte, Jean
<person> French histologist, 1866-1948. ... See: Nageotte cells. ... (05 Mar 2000) ...

naiad
1. A water nymph; one of the lower female divinities, fabled to preside over some body of fresh water, as a lake, river, brook, or fountain. ... 2. <zoology> Any species of a tribe (Naiades) of freshwater bivalves, including Unio, Anodonta, and numerous allied genera; a river mussel. ... 3. <zoology> One of a group of butterflies. See Nym …

nail
1. <anatomy> The horny scale of plate of epidermis at the end of the fingers and toes of man and many apes. 'His nayles like a briddes claws were.' (Chaucer) ... The nails are strictly homologous with hoofs and claws. When compressed, curved, and pointed, they are called talons or claws, and the animal bearing them is said to be unguiculate; w …

nail bed
The area of the corium on which the nail rests; it is extremely sensitive and presents numerous longitudinal ridges on its surface. According to some anatomists, the nail bed is the portion covered by the body of the nail, the nail matrix being only the part on which the root of the nail rests. ... Synonym: matrix unguis, keratogenous membrane, nail …