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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

isopullulanase
<enzyme> Isolated from aspergillus niger ... Registry number: EC 3.2.1.57 ... (26 Jun 1999) ...

isopycnic
<physics> Having equal density, as different regions of a medium. ... A line or surface passing through those points in a medium, at which the density is the same as, an isopycnic line or surface. ... Origin: Iso- + Gr. Pyknos dense. ... (08 Mar 2000) ...

isopycnic zone
<chemistry> The region in density gradient centrifugation having the same density as the buoyant density of the macromolecule. ... (05 Mar 2000) ...

isopyknic
Synonym for isopycnic ... <physics> Having equal density, as different regions of a medium. ... A line or surface passing through those points in a medium, at which the density is the same as, an isopycnic line or surface. ... Origin: Iso- + Gr. Pyknos dense. ... (08 Mar 2000) ...

isopyridoxal dehydrogenase
<enzyme> Nad+ dependent; from arthrobacter cr-7 grown on pyridoxine; involved in vitamin b6 degradation ... Registry number: EC 1.1.1.- ... (26 Jun 1999) ...

isopyrocalciferol
<biochemistry> A thermal decomposition product of calciferol; a stereoisomer of pyrocalciferol and ergosterol. ... Chemical name: 9b-Ergosterol. ... (05 Mar 2000) ...

isoquinoline
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. ... 1. <chemistry> Benzo[c]pyridine; ring structure is characteristic of the group of opium alkaloids represented by papaverine. ... 2. A class of alkaloids containing the isoqui …

isoquinoline 1-oxidoreductase
<enzyme> A molybdenum-containing hydroxylase from pseudomonas diminuta; catalyses the hydroxylation of isoquinoline to 1-oxo-1,2-dihydroisoquinoline with concomitant reduction of a suitable electron acceptor; mw 95 kD ... Registry number: EC 1.14.99.- ... Synonym: isoquinoline 1-hydroxylase ... (26 Jun 1999) ...

isorhythmic dissociation
<cardiology, physiology> A-V dissociation characterised by equal or closely similar atrial and ventricular rates. ... (05 Mar 2000) ...

isoriboflavin
<chemical> A riboflavin antimetabolite, differing from riboflavin in that the methyl groups on the isoalloxazine nucleus are in the 6,7 positions rather than the 7,8. ... Chemical name: 8-Demethyl-6-methylriboflavin. ... (05 Mar 2000) ...

isorrhoea
Equality of intake and output of water; maintenance of water equilibrium. ... Origin: iso-+ G. Rhoia, a flow ... (05 Mar 2000) ...

isosbestic
<chemistry> Wavelength at which the absorption coefficients of equimolar solutions of two different substances are identical. ... (18 Nov 1997) ...

isosbestic point
<physics> In applied spectroscopy, a wavelength at which absorbance of two substances, one of which can be converted into the other, is the same. ... (05 Mar 2000) ...

isoschisomer
<molecular biology> One of several restriction endonucleases which are isolated from different sources but which break a DNA molecule at the same recognition site. ... (09 Oct 1997) ...

isoschizomer
<molecular biology> A pair of restriction enzymes specific for the same recognition sequence. ... (14 Nov 1997) ...

isosensitise
Synonym for autosensitise ... To sensitise against one's own body cells. ... Synonym: isosensitise. ... (05 Mar 2000) ...

isoserum treatment
Therapeutic use of serum taken from a person having or having had the same disease as the patient under treatment. ... (05 Mar 2000) ...

isosexual
1. Relating to the existence of characteristics or feelings of both sexes in one person. ... 2. Descriptive of an individual's somatic characteristics, or of processes occurring within, that are consonant with the sex of that individual. ... (05 Mar 2000) ...

isosmotic
<physiology> Having the same total osmotic pressure or osmolality as another fluid (ordinarily intracellular fluid); such a fluid is not isosmotic if it includes solutes that freely permeate cell membranes. ... Synonym: iso-osmotic. ... (05 Mar 2000) ...

isosorbide
<chemical> 1,4:3,6-dianhydro d-glucitol. Chemically inert osmotic diuretic used mainly to treat hydrocephalus; also used in glaucoma. ... Pharmacological action: diuretics, osmotic. ... Chemical name: D-Glucitol, 1,4:3,6-dianhydro- ... (12 Dec 1998) ...

isosorbide dinitrate
<chemical> A vasodilator used in the treatment of angina. Its actions are similar to nitroglycerin but with a slower onset of action. ... Pharmacological action: vasodilator agents. ... Chemical name: D-Glucitol, 1,4:3,6-dianhydro-, dinitrate ... (12 Dec 1998) ...

isospora
A genus of protozoan parasites found in the intestines of birds, amphibians, reptiles, and mammals, including man. The oocysts produce two sporocysts, each with four sporozoites. Many species are parasitic in wild and domestic animals. ... (12 Dec 1998) ...

Isospora belli
A relatively rare species occurring in the small intestine of man, most common in the tropics but probably of worldwide distribution; most infections are subclinical, but sometimes they may cause mucous diarrhoea. ... (05 Mar 2000) ...

Isospora bigemina
A species that occurs in the small intestine of the dog, cat, fox, mink, and possibly other carnivores; the most pathogenic coccidium in dogs and cats, causing enteritis and diarrhoea; the oocysts are usually sporulated when passed in the faeces, but are indistinguishable from those of Toxoplasma gondii, so considerable question remains as to the s …

Isospora canis
A species of worldwide distribution that is mildly pathogenic in dogs and is not infective in cats. ... (05 Mar 2000) ...

Isospora felis
A species found in the small intestine and sometimes the caecum and colon of cats, lions, and other felids; it is only slightly, if at all, pathogenic in cats and is not infective in dogs. ... (05 Mar 2000) ...

Isospora rivolta
A species that occurs in the small intestine of dogs, cats, dingos, and probably other wild carnivores; pathogenic capabilities are similar to those of Isospora bigemina. ... (05 Mar 2000) ...

Isospora suis
A species that affects the small intestine of the pig, producing mild diarrhoea. ... (05 Mar 2000) ...

isosporiasis
Disease caused by infection with a species of Isospora, such as I. Belli of humans; human disease usually is mild except in cases of immunosuppression, as in AIDS, where it may cause an intractable diarrhoea. ... (05 Mar 2000) ...

isostere
One of two or more atoms or molecules having the same electron arrangement; e.g., N2 and CO. ... Origin: iso-+ G. Stereos, solid ... (05 Mar 2000) ...

isostery
Physiological enzyme or metabolic regulation via competitive inhibition by structural analogs of natural substrates. ... (05 Mar 2000) ...

isosthenuria
A state in chronic renal disease in which the kidney cannot form urine with a higher or a lower specific gravity than that of protein-free plasma; specific gravity of the urine becomes fixed around 1.010, irrespective of the fluid intake. ... Origin: iso-+ G. Sthenos, strength, + ouron, urine ... (05 Mar 2000) ...

isosuccinic acid
Synonym for methylmalonic acid ... <chemical> Methylpropanedioic acid. A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to s …

isosulfamerazine
Synonym for sulfaperin ... N'-(5-methyl-2-pyrimidinyl)sulfanilamide;an antimicrobial agent of the sulfonamide group. ... Synonym: isosulfamerazine. ... (05 Mar 2000) ...

isosulfan blue
C27H31N2NaO6S2;a dye used as a radiographic adjunct to mark lymphatic vessels during lymphography. ... (05 Mar 2000) ...

isotherm
<physics> A line connecting or marking points on the earth's surface having the same temperature. This may be the temperature for a given time of observation, or the mean temperature for a year or other period. Also, a similar line based on the distribution of temperature in the ocean. ... Origin: Iso- + Gr. Heat, fr. Hot. ... Source: Websters …

isothermal
Refers to a reaction or process that occurs at a constant temperature. ... (09 Oct 1997) ...

isothiocyanate
The radical of isothiocyanic acid, -N==C==S. ... (05 Mar 2000) ...

isothiocyanates
Organic compounds with the general formula r-ncs. ... (12 Dec 1998) ...

isothipendyl
10-(2-Dimethylamino-2-methylethyl)-10H-pyrido[3,2-b][1,4]benzothiazine;an antihistaminic. ... (05 Mar 2000) ...

isothiuronium
<chemical> Proposed topical anti-inflammatory agent that may release histamine if given intradermally. ... Pharmacological action: anti-inflammatory agent, topical. ... Chemical name: Carbamimidothioic acid, 10-undecenyl ester, monohydriodide ... (12 Dec 1998) ...

isotone
<radiobiology> Two or more nuclides having the same neutron number. ... (16 Dec 1997) ...

isotonia
A condition of tonic equality in which tension or osmotic pressure in two substances or solutions is the same. ... Origin: iso-+ G. Tonos, tension ... (05 Mar 2000) ...

isotonic
<physiology> A biological term denoting a solution in which body cells can be bathed without a net flow of water across the semipermeable cell membrane. Also, denoting a solution having the same tonicity as some other solution with which it is compared, such as physiologic salt solution and the blood serum. ... (18 Nov 1997) ...

isotonic coefficient
The amount of salts in the blood plasma, or the amount that should be added to distilled water in order to prepare an isotonic solution. ... (05 Mar 2000) ...

isotonic contraction
Contraction of a muscle, the tension remaining constant. Since the contractile force is proportional to the overlap of the filaments and the overlap is varying, the numbers of active cross bridges must be changing. ... (18 Nov 1997) ...

isotonic exercise
Synonym for isotonic contraction ... Contraction of a muscle, the tension remaining constant. Since the contractile force is proportional to the overlap of the filaments and the overlap is varying, the numbers of active cross bridges must be changing. ... (18 Nov 1997) ...

isotonic solution
One that has the same salt concentration as cells and blood. ... (12 Dec 1998) ...

isotonic solutions
Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. ... (12 Dec 1998) ...

isotonic traction
Traction in which the amount of force does not change. ... (05 Mar 2000) ...

isotonicity
1. The quality of possessing and maintaining a uniform tone or tension. ... 2. The property of a solution in being isotonic. ... (05 Mar 2000) ...

isotope
<radiobiology> One of several nuclides having the same number of protons in their nuclei and hence having the same atomic number, but differing in the number of neutrons and therefore, in the mass number. Almost identical chemical properties exist between isotopes of a particular element. The use of this term as a synonym for nuclide is to be …

isotope clearance
The rate at which an isotope is removed (usually by blood flow) from a tissue or organ such as the brain. ... (05 Mar 2000) ...

isotope labeling
Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labelled substances unless the methods of labeling are substantively discussed. Tracers that may be labelled include chemical substances, cells, or microorganisms. ... (12 Dec 1998) ...

isotopes
Atomic species differing in mass number but having the same atomic number. ... (12 Dec 1998) ...

isotopic
Of identical chemical composition but differing in some physical property, such as atomic weight. ... (05 Mar 2000) ...

isotransplantation
Transfer of an isograft (syngraft). ... (05 Mar 2000) ...

isotretinoin
<chemical> 13-cis-retinoic acid. A topical dermatologic agent that is used in the treatment of acne vulgaris and several other skin diseases. The drug has teratogenic and other adverse effects. ... Pharmacological action: keratolytic agents, teratogens. ... Chemical name: Retinoic acid, 13-cis- ... (12 Dec 1998) ...

isotropic
<radiobiology> Adjective which describes a medium whose physical properties are independent of the direction in which they are measured. ... (09 Oct 1997) ...

isotropic disk
Synonym for I band ... <cell biology> The isotropic band of the sarcomere of striated muscle, where only thin filaments are found. Unlike the A band, the I band can vary in width depending upon the state of contraction of the muscle when fixed. ... (18 Nov 1997) ...

isotropic environment
Environments in which the properties are the same at all points and there are no vectorial or axial cues. ... (18 Nov 1997) ...

isotropic lipid
A lipid occurring in the form of singly refractive droplets. ... (05 Mar 2000) ...

isotype
1. <immunology> Applied to a set of macromolecules sharing some features in common. In immunology isotype describes the class, subclass, light chain type and subtype of an immunoglobulin. ... 2. Antigenic determinant that is uniquely present in individuals of a single species. ... 3. <statistics> A conventionalised method for the graphica …

isotype switching
<immunology> The switch of immunoglobulin isotype that occurs, for example: as the immune response progresses (IgM to IgG). The switch from IgM to IgG involves only the constant region of the heavy chains (from _ to _), the light chain and variable regions of the heavy chain remaining the same and involves the switch regions, upstream (on the …

isotypic
Pertaining to an isotype. ... (05 Mar 2000) ...

isotypic variation
<immunology> Variability of antigens common to all members of a species, for example the five classes of immunoglobulins found in humans. ... See: idiotype and allotype. ... (18 Nov 1997) ...

isovaleric acid
(CH3)2CHCH2COOH; 3-Methylbutyric acid;a metabolic intermediate in oxidative processes; elevated in cases of isovaleric acidemia. ... (05 Mar 2000) ...

isovaleric acidemia
A disorder of leucine metabolism characterised by the excessive production of isovaleric acid upon protein ingestion or during infectious episodes; severe metabolic acidosis results from the large quantities of acid formed; autosomal recessive inheritance; due to a deficiency of isovaleryl-CoA dehydrogenase. ... Synonym: sweaty feet syndrome. ... (05 …

isovaleryl-CoA
The condensation product of isovaleric acid and coenzyme A; an intermediate in the catabolism of l-leucine. ... Synonym: isovalerylcoenzyme A. ... Isovaleryl-CoA dehydrogenase, an enzyme that participates in the catabolism of l-leucine; it converts isovaleryl-CoA to 3-methylcrotonyl-CoA using FAD; a deficiency in this enzyme will result in isovaleric …

isovalerylcoenzyme A
Synonym for isovaleryl-CoA ... The condensation product of isovaleric acid and coenzyme A; an intermediate in the catabolism of l-leucine. ... Synonym: isovalerylcoenzyme A. ... Isovaleryl-CoA dehydrogenase, an enzyme that participates in the catabolism of l-leucine; it converts isovaleryl-CoA to 3-methylcrotonyl-CoA using FAD; a deficiency in this en …

isovalthine
(CH3)2CHCH(COOH)-S-CH2CH(NH2)COOH; S-(1-carboxy-2-methylpropyl)-l-cysteine;a sulfur-containing compound found in urine. ... (05 Mar 2000) ...

isovolume
at the same or equal volume. ... See: isovolumic. ... (05 Mar 2000) ...

isovolume pressure-flow curve
The relationship between transpulmonary pressure and respiratory air flow, expressed as a function of lung volume. ... (05 Mar 2000) ...

isovolumetric
Synonym for isovolumic ... Occurring without an associated alteration in volume, as when, in early ventricular systole, the muscle fibres initially increase their tension without shortening so that ventricular volume remains unaltered. ... See: isometric. ... Synonym: isochoric, isovolumetric. ... (05 Mar 2000) ...

isovolumetric relaxation
Synonym for isovolumic relaxation ... That part of the cardiac cycle between the time of aortic valve closure and mitral opening, during which the ventricular muscle decreases its tension without lengthening so that ventricular volume remains unaltered; the heart is never precisely isovolumetric (vs. Isovolumic) except during long diastoles with a m …

isovolumic
Occurring without an associated alteration in volume, as when, in early ventricular systole, the muscle fibres initially increase their tension without shortening so that ventricular volume remains unaltered. ... See: isometric. ... Synonym: isochoric, isovolumetric. ... (05 Mar 2000) ...

isovolumic interval
Time during which both an A-V and a semilunar valve are closed. ... (05 Mar 2000) ...

isovolumic relaxation
That part of the cardiac cycle between the time of aortic valve closure and mitral opening, during which the ventricular muscle decreases its tension without lengthening so that ventricular volume remains unaltered; the heart is never precisely isovolumetric (vs. Isovolumic) except during long diastoles with a midiastolic period of diastasis. ... Sy …

isoxicam
Non-steroidal anti-inflammatory drug with antipyretic and analgesic properties; resembles piroxicam. ... (05 Mar 2000) ...

isoxsuprine
<chemical> A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labour. ... Pharmacological action: adrenergic beta-ag …

isoxsuprine hydrochloride
1-(p-Hydroxyphenyl)-2-[(1'-methyl-2'-phenoxy)ethylamino]-1-propanol hydrochloride;sympathomimetic amine with potent inhibitory effects on vascular, uterine, and other smooth muscles; used as a vasodilator in various vascular diseases and as a uterine relaxant. ... (05 Mar 2000) ...

isozyme
Synonym for isoenzyme ... <biochemistry> Variants of enzymes that catalyse the same reaction, but owing to differences in amino acid sequence can be distinguished by techniques such as electrophoresis or isoelectric focusing. ... Different tissues often have different isoenzymes. The sequence differences generally confer different enzyme kineti …

isradipine
<chemical> 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methyl ethyl ester. A potent calcium channel antagonist that is highly selective for vascular smooth muscle. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure. ... Pharmacological action …

issues
Unresolved conflicts regarding alternative uses of available resources. Subjects of public interest. ... (05 Dec 1998) ...

isthmectomy
<procedure> Excision of the midportion of the thyroid. ... Origin: G. Isthmos, isthmus, + ektome, excision ... (05 Mar 2000) ...

isthmic
Denoting an anatomical isthmus. ... (05 Mar 2000) ...

isthmoparalysis
Paralysis of the velum pendulum palati and the muscles forming the anterior pillars of the fauces. ... Synonym: faucial paralysis, isthmoplegia. ... Origin: G. Isthmos, isthmus, + paralysis ... (05 Mar 2000) ...

isthmoplegia
Synonym: isthmoparalysis. ... Origin: G. Isthmos, isthmus, + plege, stroke ... (05 Mar 2000) ...

isthmus
Origin: L. Isthmus, Gr. 'isqmos a neck, a neck of land between two seas, an isthmus, especially the Isthmus of Corinth; prob. From the root of 'ienai to go; cf. Icel. Eith isthmus. See Issue. ... <geography> A neck or narrow slip of land by which two continents are connected, or by which a peninsula is united to the mainland; as, the Isthmus o …

isthmus aortae
Synonym for isthmus of aorta ... A slight constriction of the aorta immediately distal to the left subclavian artery at the point of attachment of the ductus arteriosus. ... Synonym: isthmus aortae. ... (05 Mar 2000) ...

isthmus cartilaginis auris
Synonym for isthmus of cartilage of ear ... A narrow bridge connecting the cartilage of the external acoustic meatus and the lamina of the tragus with the main portion of the cartilage of the auricle. ... Synonym: isthmus cartilaginis auris. ... (05 Mar 2000) ...

isthmus faucium
Synonym for isthmus of fauces ... The constricted and short space which establishes the connection between the cavity of the mouth and the oro-pharynx, bounded anteriorly by the palatoglossal folds and posteriorly by the palatopharyngeal folds; the lateral well is the tonsillar fossa. ... Synonym: isthmus faucium. ... (05 Mar 2000) ...

isthmus glandulae thyroideae
Synonym for isthmus of thyroid ... The central part of the thyroid gland joining the two lateral lobes. ... Synonym: isthmus glandulae thyroideae. ... (05 Mar 2000) ...

isthmus gyri cinguli
Synonym for isthmus of cingulate gyrus ... The narrowing of the cingulate gyrus, at its transition with the hippocampal gyrus behind and below the splenium of the corpus callosum, caused by the anterior extension of the conjoined parieto-occipital and calcarine sulci. ... Synonym: isthmus gyri cinguli, isthmus of gyrus fornicatus, isthmus of limbic l …

isthmus meatus acustici externi
Synonym for isthmus of external acoustic meatus ... The narrowest portion of this canal in the bony part near its deep termination. ... Synonym: isthmus meatus acustici externi. ... (05 Mar 2000) ...

isthmus of aorta
A slight constriction of the aorta immediately distal to the left subclavian artery at the point of attachment of the ductus arteriosus. ... Synonym: isthmus aortae. ... (05 Mar 2000) ...

isthmus of auditory tube
The narrowest portion of the auditory tube at the junction of the cartilaginous and bony portions. ... Synonym: isthmus tubae auditivae, isthmus of eustachian tube. ... (05 Mar 2000) ...

isthmus of cartilage of ear
A narrow bridge connecting the cartilage of the external acoustic meatus and the lamina of the tragus with the main portion of the cartilage of the auricle. ... Synonym: isthmus cartilaginis auris. ... (05 Mar 2000) ...

isthmus of cingulate gyrus
The narrowing of the cingulate gyrus, at its transition with the hippocampal gyrus behind and below the splenium of the corpus callosum, caused by the anterior extension of the conjoined parieto-occipital and calcarine sulci. ... Synonym: isthmus gyri cinguli, isthmus of gyrus fornicatus, isthmus of limbic lobe. ... (05 Mar 2000) ...

isthmus of eustachian tube
Synonym for isthmus of auditory tube ... The narrowest portion of the auditory tube at the junction of the cartilaginous and bony portions. ... Synonym: isthmus tubae auditivae, isthmus of eustachian tube. ... (05 Mar 2000) ...