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mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


iodine-fast
Denoting hyperthyroidism unresponsive to iodine therapy, which develops frequently in most cases so treated. ... (05 Mar 2000) ...

iodine-induced hyperthyroidism
Synonym for Jod-Basedow phenomenon ... <endocrinology> Induction of thyrotoxicosis in a previously euthyroid individual as a result of exposure to large quantities of iodine. ... It occurs most often in areas of endemic iodine-deficient goiter and in patients with multinodular goiter. It can also can develop following use of iodine-containing a …

iodinophil
1. Staining readily with iodine. ... Synonym: iodinophilous. ... 2. Any histologic element that stains readily with iodine. ... Origin: iodine + G. Philos, fond ... (05 Mar 2000) ...

iodinophilous
Synonym for iodinophil ... 1. Staining readily with iodine. ... Synonym: iodinophilous. ... 2. Any histologic element that stains readily with iodine. ... Origin: iodine + G. Philos, fond ... (05 Mar 2000) ...

iodipamide
<chemical> A water-soluble iodinated radiographic contrast medium used for intravenous cholangiography and cholecystography. ... Pharmacological action: contrast media. ... Chemical name: Benzoic acid, 3,3'-((1,6-dioxo-1,6-hexanediyl)diimino)bis(2,4,6-triiodo- ... (12 Dec 1998) ...

iodised collodion
A 5% solution of iodine in flexible collodion; a counterirritant. ... (05 Mar 2000) ...

iodised oil
<chemical> Iodinated vegetable oil. The mixture contains 38-42% organically combined iodine that is used as a diagnostic aid (radiopaque medium). ... Pharmacological action: contrast media. ... Chemical name: Fats and Glyceridic oils, vegetable, iodinated ... (12 Dec 1998) ...

iodixanol
5,5'-[(2-Hydroxy-1,3-propane)bis(acetylamino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide];a dimeric, nonionic, low osmolar, water-soluble radiographic contrast medium for intravascular use. ... (05 Mar 2000) ...

iodo-
<chemistry, prefix> A prefix, or combining from, indicating iodine as an ingredient; as, iodoform. ... (29 Oct 1998) ...

iodoacetamide
<chemical> 2-iodoacetamide. An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate. ... Pharmacological action: enzyme inhibitors, alkylating agents, sulfhydryl reagents. ... Chemical name: Acetamide, 2-iodo- ... (12 Dec 1998) ...

iodoacetates
<chemical> Iodinated derivatives of acetic acid. Iodocacetates are commonly used as alkylating sulfhydryl reagents and enzyme inhibitors in biochemical research. ... Pharmacological action: alkylating agents, enzyme inhibitors, sulfhydryl reagents. ... (12 Dec 1998) ...

iodoalphionic acid
Beta-(4-Hydroxy-3,5-diiodophenyl)-alpha-phenylpropionic acid;a formerly used radiographic contrast medium for cholecystography. ... (05 Mar 2000) ...

iodocasein
A compound of iodine with casein, in which the iodine is attached to tyrosine molecules; possesses thyroxine activity. ... (05 Mar 2000) ...

iodochlorhydroxyquin
Iodochlorohydroxyquinoline ... 5-Chloro-7-iodo-8-quinolinol; 5-chloro-8-hydroxy-7-iodoquinoline;used topically as a local anti-infective and in a wide range of dermatoses, intravaginally in Trichomonas vaginalis vaginitis, and internally for the treatment of mild or asymptomatic intestinal amoebiasis. ... Synonym: chloriodoquin, clioquinol. ... (05 Ma …

iodochlorol
Synonym for chloriodised oil ... Chlorinated and iodised peanut oil formed by the chemical addition of iodine monochloride; formerly used for radiography of sinus and bronchi. ... Synonym: iodochlorol. ... (05 Mar 2000) ...

iododerma
An eruption of follicular papules and pustules, or a granulomatous lesion, caused by iodine toxicity or sensitivity. ... (05 Mar 2000) ...

iodoform
<chemistry> A yellow, crystalline, volatile substance, CI3H, having an offensive odour and sweetish taste, and analogous to chloroform. It is used in medicine as a healing and antiseptic dressing for wounds and sores. ... Compare: chloroform. ... (27 Oct 1998) ...

iodoglobulin
Synonym for thyroglobulin ... <biochemistry> The 650 kD protein of the thyroid gland that binds thyroxine. ... (18 Nov 1997) ...

iodogorgoic acid
3,5-Diiodotyrosine;a precursor of thyroxine. ... (05 Mar 2000) ...

iodohippurate sodium
Sodium o-iodohippurate;a radiopaque compound formerly used intravenously, orally, or for retrograde urography. When tagged with iodine-131, it was used to measure effective renal plasma flow and to image the kidneys for radioisotopic renography. ... (05 Mar 2000) ...

iodohippuric acid
<chemical> A radiopaque iodine-containing compound that has been used as a radiopaque medium in pyelography; when labelled with radioiodine, it is used for radionuclide studies of renal function. ... Pharmacological action: contrast media. ... Chemical name: Glycine, N-(2-iodobenzoyl)- ... (12 Dec 1998) ...

iodomethamate sodium
N-Methyl-3,5-diiodo-4-pyridone-2,6-dicarboxylate;a high osmolar, ionic, water-soluble, radiographic contrast medium formerly used widely as the disodium salt for intravenous urography. ... (05 Mar 2000) ...

iodometric
Relating to iodometry. ... (05 Mar 2000) ...

iodometry
Analytical techniques involving titrations in which iodine is either formed or consumed, the sudden appearance or disappearance of iodine marking the end point. ... Synonym: iodimetry. ... Origin: iodine + G. Metron, measure ... (05 Mar 2000) ...

iodopanoic acid
Synonym for iopanoic acid ... <chemical> 3-amino-alpha-ethyl-2,4,6-triiodobenzenepropanoic acid. Radiopaque medium used as diagnostic aid. ... Pharmacological action: contrast media. ... Chemical name: Benzenepropanoic acid, 3-amino-alpha-ethyl-2,4,6-triiodo- ... (12 Dec 1998) ...

iodophendylate
Synonym for iophendylate ... <chemical> Ethyl-10(p-iodophenyl)undecylate. A mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. ... Pharmacological action: contrast media. ... Chemical name: Benzenedecanoic acid, 4-iodo-iota-methyl-, ethyl ester ... (12 Dec 1998) ...

iodophil granule
A granule that stains brown with iodine; found in many of the polymorphonuclear leukocytes in pneumonia, erysipelas, scarlet fever, and various other acute diseases. ... (05 Mar 2000) ...

iodophilia
An affinity for iodine, as manifested by some leukocytes in certain conditions. When treated with a solution of iodine and potassium iodide, normal polymorphonuclear leukocytes stain a fairly bright yellow; in certain pathologic conditions, the polymorphonuclear leukocytes frequently stain diffusely brown or yellow-brown; the reaction may be intrac …

iodophor
A combination of iodine with a surfactant carrier, usually polyvinylpyrrolidone. Commercial preparations generally contain 1% 'available' iodine, which is slowly released to take effect against microorganisms; used as skin disinfectants, particularly for surgical scrubs. ... Synonym: tamed iodine. ... Origin: iodine + G. Phora, a carrying ... (05 Mar …

iodophors
<chemical> Complexes of iodine and non-ionic surface-active agent acting as carrier and solubilizing agent for the iodine in water. Iodophors usually enhance bactericidal activity of iodine, reduce vapor pressure and odour, minimise staining, and allow wide dilution with water. ... Pharmacological action: anti-infective agents, local. ... (12 D …

iodophthalein
A radiographic contrast medium. The disodium salt was once used in radiography of the gallbladder. ... Synonym: tetraiodophenolphthalein sodium. ... (05 Mar 2000) ...

iodopropylidene glycerol
Synonym for iodinated glycerol ... A form of organically bound iodine which liberates iodine systemically. Has been used as a medicinal source of iodine and as an expectorant in place of inorganic iodides such as potassium iodide. ... Synonym: iodopropylidene glycerol, organidin. ... (05 Mar 2000) ...

iodoproteins
Proteins containing iodine bound to tyrosine groups. ... (05 Mar 2000) ...

iodopsin
A visual pigment, composed of 11-cis-retinal bound to an opsin, found in the cones of the retina. ... Synonym: visual violet. ... Origin: G. Ion, violet, + ops, eye, + -in ... (05 Mar 2000) ...

iodopyracet
<chemical> An ionic monomeric contrast medium that was formerly used for a variety of diagnostic procedures. ... Pharmacological action: contrast media. ... Chemical name: 1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, compd. With 2,2'-iminobis(ethanol) (1:1) ... (12 Dec 1998) ...

iodopyridones
Iodinated pyridine derivatives that are often used as contrast media. ... (12 Dec 1998) ...

iodoquinol
<chemical> 5,7-diiodo-8-quinolinol. One of the halogenated 8-quinolinols widely used as an intestinal antiseptic, especially as an antiamebic agent. It is also used topically in other infections and may cause CNS and eye damage. It is known by very many similar trade names world-wide. ... Pharmacological action: amebicides, anti-infective agen …

iodotherapy
Treatment with iodine. ... (05 Mar 2000) ...

iodothyronines
Iodinated derivatives of thyronine. ... (05 Mar 2000) ...

iodotyrosine
<chemical> Chemical name: L-Tyrosine, iodo- ... (12 Dec 1998) ...

iodotyrosine deiodase
Synonym for iodide peroxidase ... <enzyme> A haemprotein that catalyses the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly proteins. ... Chemical name: Iodide:hydrogen-peroxide oxidoreductase ... Registry number: EC 1.11.1.8 ... (12 Dec 1998) ...

iodotyrosine deiodinase defect
See: familial goiter. ... (05 Mar 2000) ...

iodoxamate meglumine
3,3'-[Ethylenebis(oxyethylene-oxyethylenecar bonylimino)]bis-[2,4,6-triiodobenzoic acid] compound with 1-deoxy-1-(methylamino)-d-glucitol (1:2);the methylglucamine salt of an ionic, water-soluble, dimeric, radiographic contrast medium; formerly used primarily for intravenous cholangiography. ... (05 Mar 2000) ...

ioduria
Urinary excretion of iodine. ... (05 Mar 2000) ...

ioglycamic acid
<chemical> 3,3'-[oxybis((1-oxo-2,1-ethanediyl)imino)]bis(2,4,6-triiodo-benzoic acid). Radiopaque medium; a mixture of its meglumine and sodium salts is used to visualise the biliary tract. ... Pharmacological action: contrast media. ... Chemical name: Benzoic acid, 3,3'-(oxybis((1-oxo-2,1-ethanediyl)imino))bis(2,4,6-triiodo- ... (12 Dec 1998) …

iohexol
<chemical> 5-(acetyl(2,3-dihydroxypropyl)amino)-n,n'-bis(2,3- dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide. An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low che …

iometer
An apparatus for measuring ionization. ... Origin: ion + G. Metron, measure ... (05 Mar 2000) ...

ion
<chemistry, radiobiology> Atomic particle, atom or chemical radical bearing an electric charge, either negative or positive. ... (16 Dec 1997) ...

ion channel
<cell biology> A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. ... Some degree of ion specificity is usually observed and typically a million ions per second may flow. Channels may be permanently open, like the potassium leak channel or they may be voltage gated, …

ion channel gating
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability. ... (12 Dec 1998) ...

ion channels
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for channel gating can be a membrane potential, drug, transmitter, cytoplasmic messenger, or a mechanical deformation. Ion channels which are integral parts of ionotropic neurotransmitter receptors are not included. ... (12 Dec 1998) ...

ion cyclotron emission
<radiobiology> As ions gyrate around in a magnetic field (see also larmor radius or cyclotron radius), they radiate radio-frequency electromagnetic waves. This is known as ion cyclotron emission, and can be measured to help diagnose a plasma. ... (09 Oct 1997) ...

ion exchange
Reversible chemical reaction between a solid, often an ion exchange resin, and a fluid whereby ions may be exchanged from one substance to another. This technique is used in water purification, in research, and in industry. ... (12 Dec 1998) ...

ion exchange chromatography
<procedure> Separation of molecules by absorption and desorption from charged polymers. An important technique for protein purification. ... For small molecules the support is usually polystyrene, but for macromolecules, cellulose, acrylamide or agarose supports give less non-specific absorption and denaturation. Typical charged residues are C …

ion exchange resin
<chemistry> A resin of polymers that havefixed charged groups which is used in chromatographic columns to separate ions. ... (27 Oct 1998) ...

ion exchange resins
<chemistry> High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ion exchange) with either cations or anions. ... See: ion exchange, ion exchanger. ... (12 Dec 1998) ...

ion exchanger
See: anion exchanger, cation exchanger. ... (05 Mar 2000) ...

ion pump
A membranal complex of proteins that is capable of transporting ions against a concentration gradient using the energy from ATP. ... (05 Mar 2000) ...

ion pumps
Integral membrane proteins that transport ions across a membrane against an electrochemical gradient. ... (12 Dec 1998) ...

ion selective electrode
An electrode half cell, with a semi permeable membrane that is permeable only to a single ion. The electrical potential measured between this and a reference half cell (e.g. A calomel electrode) is thus the Nernst potential for the ion. Given that the solution filling the ion selective electrode is known, the activity (rather than concentration) of …

ion transport
The movement of ions across energy-transducing cell membranes. Transport can be active or passive. Passive ion transport (facilitated diffusion) derives its energy from the concentration gradient of the ion itself and allows the transport of a single solute in one direction (uniport). Active ion transport is usually coupled to an energy-yielding ch …

ion-selective electrodes
Electrodes which can be used to measure the concentration of particular ions in cells, tissues, or solutions. ... (12 Dec 1998) ...

ionic
Relating to an ion. ... (05 Mar 2000) ...

ionic coupling
<chemistry> The same as electrical coupling. ... (18 Nov 1997) ...

ionic medication
Synonym for iontophoresis ... Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow. ... (18 Nov 1997) ...

ionic strength
Symbolised as g/2 or I and set equal to 0.5&sigma;mizi2, where mi equals the molar concentration and zi the charge of each ion present in solution; if molar concentrations (ci) are used instead of molality (and the solution is dilute), then I == 0.5(1/&rho;o)&sigma;cizi2 where &rho;o is the density of the solvent; a number of bioche …

ionisation
<chemistry, radiobiology> Any process by which a neutral atom gains or loses electrons, thus acquiring a net charge, as the dissociation of a substance in solution into ions or ion production by the passage of radioactive particles. ... High temperatures, electrical discharges or nuclear radiations can cause ionisation. ... (16 Dec 1997) ...

ionisation energy
<radiobiology> Generally refers to the amount of energy required to strip a particular electron from an atom. The first ionisation energy is a commonly used quantity in many fields of physics and chemistry. ... Typically measured in electron-volts. Equivalent to the atomic binding energy of the electron. ... (09 Oct 1997) ...

ionise
To separate into ions; to dissociate atoms or molecules into electrically charged atoms or radicals. ... (05 Mar 2000) ...

ionised atom
<chemistry> An atom that possesses an electrostatic charge as a result of loss or gain of electrons; e.g., H+, Calcium, Cl-, O2-. ... (05 Mar 2000) ...

ionised calcium
<biochemistry> The ionised calcium represents the calcium (Ca++) that is the metabolically active calcium. Normal values for ionised calcium in the bloodstream should be 4.4 to 5.3 mg/dl for adults and 4.4 to 6.0 mg/dl for children. Elevations may be seen in hyperparathyroidism, metastatic bone tumour, milk-alkali syndrome, multiple myeloma, …

ionising radiation
<radiobiology> Radiation sufficiently energetic to dislodge electrons from an atom. Ionising radiation includes x and gamma radiation, electrons (beta radiation), alpha particles (helium nuclei) and heavier charge atomic nuclei. Neutrons ionise indirectly by colliding with atomic nuclei. ... Alpha and gamma radiation are far more effective at …

ionium
Former term for thorium-230. ... Origin: G. Ion, going ... (05 Mar 2000) ...

ionization
Synonym for ionisation ... <chemistry, radiobiology> Any process by which a neutral atom gains or loses electrons, thus acquiring a net charge, as the dissociation of a substance in solution into ions or ion production by the passage of radioactive particles. ... High temperatures, electrical discharges or nuclear radiations can cause ionisatio …

ionization chamber
A chamber for detecting ionization of the enclosed gas; used for determining intensity of ionizing radiation. ... (05 Mar 2000) ...

ionizing radiation
Corpuscular (e.g., neutrons, electrons) or electromagnetic (e.g., gamma) radiation of sufficient energy to ionise the irradiated material. ... (05 Mar 2000) ...

ionogram
The result of ionography. ... (18 Nov 1997) ...

ionomycin
<chemical> A divalent calcium ionophore that is widely used as a tool to investigate the role of intracellular calcium in cellular processes. ... Pharmacological action: ionophores. ... Chemical name: Ionomycin ... (12 Dec 1998) ...

ionone
A cyclic ketone with an odour of violets or cedar wood, the a and b varieties of which differ in the location of the double bond in the ring: provitamins A and vitamin A have ionone configuration in the ring portion; alpha-carotene contains one alpha-and one beta-ionone moieties, beta-carotene contains two beta-ionone moieties, and gamma-carotene c …

ionopherogram
Synonym for electropherogram ... <chemistry> The densitometric or colourimetric pattern obtained from filter paper or similar porous strips on which substances have been separated by electrophoresis; may also refer to the strips themselves. ... Synonym: electrophoretogram, ionogram, ionopherogram. ... (05 Mar 2000) ...

ionophore
<chemistry> A molecule that allows ions to cross lipid bilayers. There are two classes: carriers and channels. Carriers, like valinomycin, form cage like structures around specific ions, diffusing freely through the hydrophobic regions of the bilayer. Channels, like gramicidin, form continuous aqueous pores through the bilayer, allowing ions …

ionophores
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the …

ionophoresis
Synonym: electrophoresis. ... Origin: ion + G. Phoresis, a carrying ... (05 Mar 2000) ...

ionophoretic
Synonym for electrophoretic ... Relating to electrophoresis, as an electrophoretic separation. ... Synonym: ionophoretic. ... (05 Mar 2000) ...

ionosphere
<radiobiology> Ionised region of the upper earth atmosphere, which behaves like a plasma, including reflection of AM radio waves and generation of auroral glows. ... (09 Oct 1997) ...

ions
Atoms or radicals having a charge of positive (cation) or negative (anion) electricity owing to the loss (positive) or gain (negative) of one or more electrons. ... (12 Dec 1998) ...

iontophoresis
Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow. ... (18 Nov 1997) ...

iontophoretic
Relating to iontophoresis. ... (05 Mar 2000) ...

iontotherapy
Synonym for iontophoresis ... Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow. ... (18 Nov 1997) ...

iopamidol
<chemical> An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures. Its non-ionic, water-soluble properties result in optimal imaging and reduced toxicity. ... Pharmacological action: contrast media. ... Chemical name: 1,3-Benzenedicarbo …

iopanoic acid
<chemical> 3-amino-alpha-ethyl-2,4,6-triiodobenzenepropanoic acid. Radiopaque medium used as diagnostic aid. ... Pharmacological action: contrast media. ... Chemical name: Benzenepropanoic acid, 3-amino-alpha-ethyl-2,4,6-triiodo- ... (12 Dec 1998) ...

iopentol
N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl) acetamido]-2,4,6-triiodoisophthalamide;a nonionic, monomeric, low osmolar radiographic contrast medium for intravenous urography or angiography. ... (05 Mar 2000) ...

iophendylate
<chemical> Ethyl-10(p-iodophenyl)undecylate. A mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. ... Pharmacological action: contrast media. ... Chemical name: Benzenedecanoic acid, 4-iodo-iota-methyl-, ethyl ester ... (12 Dec 1998) ...

iophenoic acid
Synonym for iophenoxic acid ... Alpha-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid;a radiographic contrast medium; formerly used for oral cholecystography. ... Synonym: iophenoic acid. ... (05 Mar 2000) ...

iophenoxic acid
Alpha-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid;a radiographic contrast medium; formerly used for oral cholecystography. ... Synonym: iophenoic acid. ... (05 Mar 2000) ...

iophobia
<psychology> Morbid fear of poisons. ... Origin: G. Ios, poison, + phobos, fear ... (05 Mar 2000) ...

iopromide
A monomeric, nonionic, water-soluble, low osmolar radiographic contrast medium for intravenous urography or angiography. ... (05 Mar 2000) ...

iota
1. The ninth letter in the Greek alphabet, &iota;. ... 2. In chemistry, denotes the ninth in a series, or the ninth atom from a carboxyl group or other functional group. ... 3. A tiny or minute amount. ... (05 Mar 2000) ...

iotacism
A speech defect marked by the frequent substitution of a long e sound (that of the Greek iota) for other vowels. ... Origin: G. Iota, the letter &iota. ... (05 Mar 2000) ...

iothalamate meglumine
<chemical> 3-(acetylamino)-2,4,6-triiodo-5-((methylamino)carbonyl) benzoic acid salt with 1-deoxy-1-(methylamino)-d-glucitol. Radiopaque medium used for urography, angiography, venography, and myelography. It is highly viscous and binds to plasma proteins. ... Pharmacological action: contrast media. ... Chemical name: D-Glucitol, 1-deoxy-1-(met …