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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

isobestic
Erroneous spelling of isosbestic. ... (05 Mar 2000) ...

isobornyl thiocyanoacetate
C13H19NO2S;a pediculicide. ... (05 Mar 2000) ...

isobutane
See: butane. ... (05 Mar 2000) ...

isobuteine
S-(2-Carboxypropyl)cysteine;a sulfur-containing compound in urine. ... (05 Mar 2000) ...

isobutyl alcohol
See: butyl alcohol. ... (05 Mar 2000) ...

isobutyl nitrite
A liquid present in commercial amyl nitrite, with similar antispasmodic and vasodilator properties. ... (05 Mar 2000) ...

isobutyric acid
See: butyric acid. ... (05 Mar 2000) ...

isobutyryl-CoA mutase
<enzyme> Catalyses conversion of butyryl-CoA to isobutyryl-CoA ... Registry number: EC 5.4.99.- ... (26 Jun 1999) ...

isobuzole
N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-methoxybenzenesulfonamide;an oral hypoglycaemic agent for the treatment of diabetes mellitus. ... Synonym: glysobuzole. ... (05 Mar 2000) ...

isocapnia
A state in which the arterial carbon dioxide pressure remains constant or unchanged. ... Origin: iso-+ G. Kapnos, vapor ... (05 Mar 2000) ...

isocarboxazid
<chemical> An mao inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. ... Pharmacological action: antidepressive agents, monoamine oxidase inhibitors. ... Chemical name: 3-Isoxazolecarboxylic acid, 5-methyl-, …

isocellular
Composed of cells of equal size or of similar character. ... Origin: iso-+ L. Cellula, dim. Of cella, a storeroom ... (05 Mar 2000) ...

isochore
<molecular biology> Long stretches of GC or at rich sequences of DNA associated with R and G chromosome bands respectively. ... (18 Nov 1997) ...

isochoric
Synonym: isovolumic. ... Origin: iso-+ G. Chora, space ... (05 Mar 2000) ...

isochromanequinone reductase
<enzyme> Converts mederrhodin a to mederrhodin b ... Registry number: EC 1.6.99.- ... Synonym: icq reductase ... (26 Jun 1999) ...

isochromatophil
Isochromatophile ... Having an equal affinity for the same dye; said of cells or tissues. ... Origin: iso-+ G. Chroma, colour, + philos, fond ... (05 Mar 2000) ...

isochromic anaemia
Synonym for normochromic anaemia ... Any anaemia in which the concentration of haemoglobin in the erythrocytes is within the normal range, i.e., the mean corpuscular haemoglobin concentration is from 32 to 36%. ... Synonym: isochromic anaemia. ... (05 Mar 2000) ...

isochromosome
An abnormal chromosome with two identical arms due to duplication of one arm and loss of the other arm. (found in some girls with turner syndrome and in tumours.) ... (12 Dec 1998) ...

isochromosomes
Metacentric chromosomes produced during meiosis or mitosis when the centromere splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each o …

isochronia
1. The state of having the same chronaxie. ... 2. Agreement, with respect to time, rate, or frequency, between processes. ... Origin: iso-+ G. Chronos, time ... (05 Mar 2000) ...

isochronous
Occurring during the same time. ... (05 Mar 2000) ...

isocitrase
Synonym for isocitrate lyase ... <enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. ... Chemical name: Isocitrate glyoxylate-lyase ... Registry number: EC 4.1.3.1 ... (12 Dec 1998) ...

isocitrate
<biochemistry> An intermediate in the tricarboxylic acid cycle (citric acid cycle). ... (18 Nov 1997) ...

isocitrate dehydrogenase
<enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting …

isocitrate lyase
<enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. ... Chemical name: Isocitrate glyoxylate-lyase ... Registry number: EC 4.1.3.1 ... (12 Dec 1998) ...

isocitric acid
HOOCCH2CH(COOH)CH(OH)COOH;an intermediate in the tricarboxylic acid cycle. ... (05 Mar 2000) ...

isocitric acid dehydrogenase
Synonym for isocitrate dehydrogenase ... <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP …

isocitritase
Synonym for isocitrate lyase ... <enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. ... Chemical name: Isocitrate glyoxylate-lyase ... Registry number: EC 4.1.3.1 ... (12 Dec 1998) ...

isocline
A line in a geographical region that joins all points at which in a population there is the same average frequency for the various alleles at a genetic locus. ... See: cline. ... Origin: iso-+ G. Klino, to slope ... (05 Mar 2000) ...

isoconazole
Antibacterial and antifungal agent related to ketoconazole and oxiconazole. ... (05 Mar 2000) ...

isocoria
Equality in the size of the two pupils. ... Origin: iso-+ G. Kore, pupil ... (05 Mar 2000) ...

isocortex
O. And C. Vogt's term for the larger part of the mammalian cerebral cortex, distinguished from the allocortex by being composed of a larger number of nerve cells arranged in six layers. ... See: cerebral cortex. ... Synonym: homotypic cortex, neocortex, neopallium. ... (05 Mar 2000) ...

isocyanate
The radical -N==C==O from isocyanic acid. ... (05 Mar 2000) ...

isocyanates
Organic compounds that contain the -nco radical. ... (12 Dec 1998) ...

isocyanic acid
HNCO;a highly reactive chemical. ... (05 Mar 2000) ...

isocyanide
The radical -NC; organic isocyanide's are called isonitriles. ... (05 Mar 2000) ...

isocyclic compound
Synonym for cyclic compound ... Any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic chemistry where: 1) numerous compound's contain rings of carbon atoms (carbocyclic compound's) or carbon atoms plus one or more atoms of other types (heterocyclic compound's), usually nitrogen, oxygen, or sulfur; 2) w …

isocytolysin
A cytolysin that reacts with the cells of certain other animals of the same species, but not with the cells of the individual that formed the isocytolysin. ... (05 Mar 2000) ...

isodactylism
Condition in which the fingers or toes are all approximately of equal length. ... Origin: iso-+ G. Daktylos, finger ... (05 Mar 2000) ...

isodense
Denoting a tissue having a radiopacity (radiodensity) similar to that of another or adjacent tissue. ... (05 Mar 2000) ...

isodesmosine
<chemical> 2-(4-amino-4-carboxybutyl)-1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinium. A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring. ... Chemical name: Pyridinium, 2-(4-amino-4-carboxybutyl)-1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)- ... ( …

isodiabatic
<physics> Pertaining to the reception or the giving out of equal quantities of heat by a substance. Isodiabatic lines or curves, a pair of lines or curves exhibiting, on a diagram of energy, the law of variation of the pressure and density of a fluid, the one during the lowering, and the other during the raising, of its temperature, when the …

isodiphasic complex
A diphasic complex whose positive and negative deflections are approximately equal. ... Synonym: equiphasic complex. ... (05 Mar 2000) ...

isodisomy
Remarkable situation where both chromosomes in a pair are from one parent and neither from the other. Isodisomy causes some birth defects and, we suspect, plays a role in cancer. Also called uniparental disomy. ... (12 Dec 1998) ...

isodulcit
Synonym for l-rhamnose ... A methylpentose present in a number of plant glycosides, free in poison sumac, in lipopolysaccharides of Enterobacteriaceae, and in rutinose (a disaccharide). ... Synonym: isodulcit. ... (05 Mar 2000) ...

isodynamic law
For energy purposes, the different foodstuffs may replace one another in accordance with their caloric values when burned in a calorimeter. ... (05 Mar 2000) ...

isodynamogenic
Synonym: isoenergetic. ... 2. Producing equal nerve force. ... Origin: iso-+ G. Dynamis, force, + -gen, producing ... (05 Mar 2000) ...

isoelectric
Of equal electrical potential. ... Compare: isoelectric point. ... Synonym: isopotential. ... Isoelectric focusing, electrophoresis of small molecules or macromolecules in a pH gradient. ... (05 Mar 2000) ...

isoelectric focusing
<technique> Electrophoresis in a stabilised pH gradient. High resolution method for separating molecules, especially proteins, that carry both positive and negative charges. Molecules migrate to the pH corresponding to their isoelectric point. The gradient is produced by electrophoresis of amphiphiles, heterogenous molecules giving a continuu …

isoelectric line
The baseline of the electrocardiogram. ... (05 Mar 2000) ...

isoelectric period
The period occurring in the electrocardiogram between the end of the S wave and the beginning of the T wave during which electrical forces are acting in directions such as to neutralise each other so that there is no difference in potential under the two electrodes. ... (05 Mar 2000) ...

isoelectric point
<biochemistry> The pH at which a protein carries no net charge. Below the isoelectric point proteins carry a net positive charge, above it a net negative charge. Due to a preponderance of weakly acid residues in almost all proteins, they are nearly all negatively charged at neutral pH. The isoelectric point is of significance in protein purif …

isoelectric zone
The range of H-ion concentration (pH) over which isoelectric precipitation occurs. ... (05 Mar 2000) ...

isoenergetic
Exerting equal force; equally active. ... Synonym: isodynamogenic. ... (05 Mar 2000) ...

isoenzyme
<biochemistry> Variants of enzymes that catalyse the same reaction, but owing to differences in amino acid sequence can be distinguished by techniques such as electrophoresis or isoelectric focusing. ... Different tissues often have different isoenzymes. The sequence differences generally confer different enzyme kinetic parameters that can som …

isoenzyme electrophoresis
Electrophoretic separation of serum enzymes; separation of lactate dehydrogenase and creatine phosphokinase is commonly used for diagnosis of acute myocardial infarction. ... (05 Mar 2000) ...

isoenzymes
One of various structurally related forms of an enzyme, each having the same mechanism but with differing chemical, physical, or immunologically characteristics. ... (12 Dec 1998) ...

isoepoxydon dehydrogenase
<enzyme> Interconversion between phyllostine (2-hydroxymethyl-5,6-epoxy-1,4-benzoquinone) and isoepoxydon (4-hydroxy-5,6-epoxycyclohex-2-en-1-one ... Registry number: EC 1.- ... (26 Jun 1999) ...

isoerythrolysis
Destruction of erythrocytes by isoantibodies. ... Origin: iso-+ erythrocyte = G. Lysis, dissolution ... (05 Mar 2000) ...

isoetharine
<chemical> Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma. ... Pharmacological action: adrenergic beta-agonists, bronchodilator agents, sympathomimetic. ... Chemical name: 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)butyl)- ... (12 Dec 1998) ...

isoflavone synthase
<enzyme> Microsomal enzyme from soybeans; converts (2s)-naringenin to genistein and converts (2s)-5,4'-dihydroxflavanone to daidzein; requires NADPH and oxygen; may be a cytochrome p-450-dependent monooxygenase ... Registry number: EC 1.14.13.- ... Synonym: genistein synthase, naringenin monooxygenase, NADPH-2'-hydroxydaidzein oxidoreductase …

isoflavone-5-O-methyltransferase
<enzyme> Yellow lupin root enzyme catalyses position-specific methylation of the 5-hydroxyl group of a number of isoflavones, has little or no activity with flavones, flavonols, coumarins or phenylpropanoids ... Registry number: EC 2.1.1.- ... Synonym: isf-methyltransferase ... (26 Jun 1999) ...

isoflavones
3-phenylchromones. Isomeric form of flavones in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position. ... (12 Dec 1998) ...

isofluorphate
[(CH3)2CH-O]2P(O)F;a toxic cholinergic agent that acts by irreversible inhibition of cholinesterase; an ophthalmic cholinergic agent; also used in biochemical research as an enzyme inhibitor. ... Synonym: diisopropyl fluorophosphate. ... (05 Mar 2000) ...

isoflurane
<chemical> 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether. A stable, non-explosive inhalation anaesthetic, relatively free from significant side effects. ... Pharmacological action: anaesthetics, inhalation. ... Chemical name: Ethane, 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro- ... (12 Dec 1998) ...

isoflurophate
<chemical> Phosphorofluoridic acid bis(l-methylethyl) ester. An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. ... Pharmacological a …

isoform
<biochemistry> A protein having the same function and similar (or identical sequence), but the product of a different gene and usually) tissue specific. Rather stronger in implication than homologous. ... (15 Oct 1997) ...

isogamete
1. One of two or more similar cells that conjugate or fuse and subsequently divide, resulting in reproduction. ... 2. A gamete of the same size as the gamete with which it unites. ... Origin: iso-+ G. Gametes or gamete, husband or wife ... (05 Mar 2000) ...

isogamy
<biology> A condition where the gametes of a species are equal in size. Generally this means that there is only one type of gamete with no sexual difference. ... (15 Oct 1997) ...

isogeneic
Synonym for syngeneic ... Relating to genetically identical individuals. ... Synonym: isogeneic, isogenic, isologous, isoplastic, syngenic. ... Origin: G. Syngenes, congenital ... (05 Mar 2000) ...

isogeneic graft
Synonym for syngraft ... A tissue or organ transplanted between genetically identical individuals. ... Synonym: isogeneic graft, isograft, isologous graft, isoplastic graft, syngeneic graft. ... (05 Mar 2000) ...

isogenic
<genetics> Of the same genotype. ... Origin: Gr. Gennan = to produce ... (14 Nov 1997) ...

isogenic strain
A strain of animals inbred for many generations and with high probability homozygous for certain specified genes. ... (05 Mar 2000) ...

isogenous
Of the same origin, as in development from the same tissue or cell. ... Origin: iso-+ G. Genos, family, kind ... (05 Mar 2000) ...

isogenous nest
A clone of cartilage cells all from one progenitor cell and occurring as a cluster. ... (05 Mar 2000) ...

isogentiobiose
Synonym for isomaltose ... <chemical> 6-0-alpha-glucopyranosyl-d-glucose. A disaccharide consisting of two glucose units in an alpha (1-6) glycosidic linkage. ... Chemical name: D-Glucose, 6-O-alpha-D-glucopyranosyl- ... (12 Dec 1998) ...

isoglutamine
H2NCO-CH(NH3+) -CH2CH2COO-;a glutamic amide. ... (05 Mar 2000) ...

isognathous
Having jaws of approximately the same width. ... Origin: iso-+ G. Gnathos, jaw ... (05 Mar 2000) ...

isograft
Synonym for syngraft ... A tissue or organ transplanted between genetically identical individuals. ... Synonym: isogeneic graft, isograft, isologous graft, isoplastic graft, syngeneic graft. ... (05 Mar 2000) ...

isogyres
<microscopy> In a uniaxial interference figure, the two black brushes that form a cross and represent the pattern of extinction positions of the crystal. In a biaxial interference figure, the two black (usually curved) brushes that intersect the isochromatic curves (lemniscates) and represent the pattern of extinction positions of the crystal …

isohaemagglutinin
<immunology> Natural antibodies that react against normal antigens of other members of the same species. ... (15 Oct 1997) ...

isohemagglutination
Synonym: isoagglutination. ... Origin: iso-+ G. Haima, blood, + L. Ad, to, + gluten, glue ... (05 Mar 2000) ...

isohemagglutinin
Synonym for isoagglutinin ... <immunology> An isoantibody that causes agglutination of cells of genetically different members of the same species. ... Synonym: isohemagglutinin. ... (05 Mar 2000) ...

isohemolysin
An isolysin that reacts with red blood cells. ... (05 Mar 2000) ...

isohemolysis
A form of isolysis in which there is dissolution of red blood cells as a result of the reaction between an isolysin (isohemolysin) and specific antigen in or on the cells. ... Origin: iso-+ G. Haima, blood, + lysis, dissolution ... (05 Mar 2000) ...

isohydric
Denoting two substances possessing the same pH. ... (05 Mar 2000) ...

isohydruria
Fixation of the pH of the urine without the usual variation. ... Origin: iso-+ G. Hydor, water, + ouron, urine, + -ia ... (05 Mar 2000) ...

isohypercytosis
An obsolete term for a condition in which the number of leukocytes in the circulating blood is increased, but the relative proportions of the various types (especially the granulocytes) are within the usual range. ... Origin: iso-+ G. Hyper, above, + kytos, cell, + -osis, condition ... (05 Mar 2000) ...

isohypocytosis
An obsolete term for a condition in which there is an abnormally small number of leukocytes in the circulating blood, but the relative proportions of the various types (especially the granulocytes) are within the usual range. ... Origin: iso-+ G. Hypo, below, + kytos, cell, + -osis, condition ... (05 Mar 2000) ...

isoimmune neonatal thrombocytopenia
Immune thrombocytopenia resulting from maternal-foetal platelet incompatibility. ... (05 Mar 2000) ...

isoimmunization
Development of a significant titre of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species; e.g., isoimmunization is likely to occur when an Rh-negative person is treated with a transfusion of Rh-positive blood from another human being, or an Rh-negativ …

isoionic point
The pH at which a zwitterion has an equal number of positive and negative charges; in water and in the absence of other solutes, this is the isoelectric point. ... (05 Mar 2000) ...

isolate
To separate from other persons, materials or objects. ... (18 Nov 1997) ...

isolated abutment
A lone-standing tooth, or root, used as an abutment with edentulous areas mesial and distal to it. ... (05 Mar 2000) ...

isolated dextrocardia
Dextrocardia with mirror transposition of the cardiac chambers but without displacement of the abdominal viscera. ... Synonym: type 2 dextrocardia. ... (05 Mar 2000) ...

isolated dyskeratosis follicularis
warty dyskeratoma ...

isolated explosive disorder
A disorder of impulse control characterised by a single episode of failure to resist a violent, externally directed act which had serious impact on others. ... (05 Mar 2000) ...

isolated limb perfusion
<oncology, procedure> Chemotherapy treatment in which blood is taken from a patient, pumped through a machine that adds anticancer drugs to the blood, then returned to the limb being treated. ... (15 Oct 1997) ...

isolated parietal endocarditis
Fibrous thickening of the endocardium of the left ventricle without valvular involvement. ... (05 Mar 2000) ...

isolated proteinuria
Proteinuria in a patient who is asymptomatic, has normal renal function and urinary sediment, and has no manifestation of systemic disease upon initial examination. ... (05 Mar 2000) ...