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mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197
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Alpers diseaseSynonym for poliodystrophia cerebri progressiva infantilis ... Familial progressive spastic paresis of extremities with progressive mental deterioration, with development of seizures, blindness and deafness, beginning during the first year of life, and with destruction and disorganization of nerve cells of the cerebral cortex. ... Synonym: Alpers dis …
Alpers, Bernard<person> U.S. Neurologist, 1900-1981. ... See: Alpers disease. ... (05 Mar 2000) ...
Alpert syndrome<syndrome> A usually inherited disorder characterised by premature closing of the cranial suture lines resulting in a peaked shaped head and abnormal facial appearance. Since it is usually autosomal dominant one or both parents also have the disorder. ... Surgery is used to correct skull and facial abnormalities. ... Inheritance: autosomal domi …
alphaFirst letter of the Greek alphabet, a. ... (05 Mar 2000) ...
alpha 1-4-mannosyltransferase<enzyme> From mycobacterium smegmatis; involved in methylmannose polysaccharide elongation; GDP-mannose is donor ... Registry number: EC 2.4.1.- ... (26 Jun 1999) ...
alpha 1,6-mannosyltransferase<enzyme> From saccharomyces cerevisiae; adds mannose residues in an alpha-1,6-linkage to man8glcnac and man9glcnac in the biosynthesis of the outer chain of yeast mannoproteins ... Registry number: EC 2.4.1.- ... (26 Jun 1999) ...
alpha alcoholismJellinek's term for a still controllable and strictly psychological dependence on alcohol, as to relieve emotional or physical pain, with resulting interference with interpersonal relationships. ... (05 Mar 2000) ...
alpha angleThe angle between the visual and optic axes as they cross at the nodal point of the eye, the angle between the visual line and the major axis of the corneal ellipse. ... (05 Mar 2000) ...
alpha blockingThe attenuation of the occipital alpha rhythm (8-14 Hz brain waves as seen on an electroencephalogram), produced by opening the eyes or by intense mental concentration. ... (05 Mar 2000) ...
alpha cell<biology> A type of cell in the pancreas (in areas called the islets of Langerhans). Alpha cells make and release a hormone called glucagon, which raises the level of glucose (sugar) in the blood. ... (09 Oct 1997) ...
Alpha cellsAlpha cell's of pancreas or of anterior lobe of hypophysis. ... (05 Mar 2000) ...
alpha cells of pancreasCell's of the islets of Langerhans that secrete glucagon. ... (05 Mar 2000) ...
alpha chain diseaseA vague or indefinite term; could be used for alpha-heavy-chain disease (a lymphoplasma cell proliferative disease usually seen in Mediterranean men, characterised by intestinal involvement with steatorrhoea, often progressive with fatal outcome) or a thalassaemia (a genetic abnormality in the alpha globin chain of haemoglobin). ... (05 Mar 2000) …
alpha emission<physics> Form of nuclear decay where the nucleus emits an alpha particle (see entry below). ... (09 Oct 1997) ...
alpha errorThe statistical error (said to be of the first kind or type I) made in testing an hypothesis when it is concluded that a result is positive when it really is not. Alpha error is often referred to as a false positive. ... (12 Dec 1998) ...
alpha fibresLarge somatic motor or proprioceptive nerve fibre's conducting impulses at rates near 100 m/sec. ... (05 Mar 2000) ...
alpha glucosidase<enzyme> An enzyme which removes the last 1,4-linked alpha-D-glucose residue from the nonreducing end of a long chain (or polymer) of such residues, making an alpha-D-glucose molecule out of it in the process. ... (09 Oct 1997) ...
alpha granuleA granule of an alpha cell that was named as the first of several kinds or because it was acidophilic. ... (05 Mar 2000) ...
alpha helix<molecular biology> A particular helical folding of the polypeptide backbone in protein molecules (both fibrous and globular), in which the carbonyl oxygens are all hydrogen bonded to amide nitrogen atoms three residues along the chain. ... The translation of amino acid residues along the long axis is 0.15 nm and the rotation per residue, 100 …
alpha interferon<cytokine> Interferon which is released by leukocytes in response to a viral infection. A protein cytokine that is used as an anticancer agent. ... (15 Nov 1997) ...
alpha methyl dopaSynonym for methyldopa ... <drug> An antihypertensive drug, preferred in pregnant patients. ... (18 Nov 1997) ...
alpha mucase<chemical> Combination of mucopolysaccharidases and chymotrypsin ... (26 Jun 1999) ...
alpha particle<physics> A radioactive particle made up of two protons and two neutrons, these particles are created by the decay of a radioactive material or by nuclear bombardment, and they are the same as the nucleus of a helium-4 atom. ... (09 Oct 1997) ...
alpha particlesPositively charged particles composed of two protons and two neutrons, i.e., helium nuclei, emitted during disintegration of very heavy isotopes; a beam of alpha particles or an alpha ray has very strong ionizing power, but weak penetrability. ... (12 Dec 1998) ...
alpha radiation<physics, radiobiology> The most easily absorbable type of radiation, it consists of a stream of alpha particles, doubly ionised helium nuclei which are electrically charged and produce intense ionisation in matter. Alpha radiation can be deflected in electromagnetic fields. ... (09 Oct 1997) ...
alpha raySynonym for alpha particle ... <physics> A radioactive particle made up of two protons and two neutrons, these particles are created by the decay of a radioactive material or by nuclear bombardment, and they are the same as the nucleus of a helium-4 atom. ... (09 Oct 1997) ...
alpha rhythmBrain waves in the encephalogram which have a frequency of 8 to 13 per second. They are typical of the normal person awake and in a quiet resting state, and occur principally in the occipital region. ... (12 Dec 1998) ...
alpha substanceSynonym for reticular substance ... A filamentous plasmatic material, beaded with granules, demonstrable by means of vital staining in the immature red blood cells. ... Synonym: alpha substance, filar mass, filar substance, substantia reticularis, substantia reticulofilamentosa. ... Synonym: reticular formation. ... (05 Mar 2000) ...
Alpha testsA set of paper and pencil-administered mental tests first used in the United States Army in 1917-1918 to determine the mental ability of literate recruits; the set includes 8 different types of tests: i.e., directions, arithmetical problems, practical judgement, synonyms and antonyms, disarrayed sentences, number series completions, analogies, and …
alpha thalassaemia<haematology> A condition characterised by the reduced synthesis of the alpha chain of haemoglobin due to abnormality in one of two or more genes that code for the synthesis of alpha-globin chains. The severity of this condition can vary from mild anaemia to death, depending on the number of genes deleted. ... Heterozygous state: severe type, …
alpha unitsCytoplasmic glycogen granules arranged in rosettes. ... (05 Mar 2000) ...
alpha viruses<virology> These are the major viruses in the Togavirus group and include eastern and western equine encephalitis viruses, the Sindbis virus and the Semliki Forest virus. The last two viruses are being researched as vectors for expressing heterologous genes. ... (09 Oct 1997) ...
alpha waveSynonym for alpha rhythm ... Brain waves in the encephalogram which have a frequency of 8 to 13 per second. They are typical of the normal person awake and in a quiet resting state, and occur principally in the occipital region. ... (12 Dec 1998) ...
alpha-(4-O-methyl)-D-glucuronidase<enzyme> Removes 4-o-methyl-glucopyranosyl uronic acid residues from the 2-position of fungal cell wall xylans ... Registry number: EC 3.2.1.- ... Synonym: 4-o-methyl-glucuronidase ... (26 Jun 1999) ...
alpha-1 antichymotrypsin<chemical> Glycoprotein found in alpha(1)-globulin region in human serum. It is an inhibiter of the digestive protease, chymotrypsin and other chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. ... The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammat …
alpha-1 antitrypsin<chemical> Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (a1pi), it exists in over 30 different biochemical variant forms known collectively as the pi (protease inhibitor) system. ... Hereditary deficiency is …
alpha-1 antitrypsin deficiency<chest medicine> Deficiency of the protease inhibitor alpha-1 antitrypsin, leads primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. ... The lack of this protein leads to damage of various organs, but mainly to the lung and liver. ... symptoms may become apparent at a very ear …
alpha-1-proteinase deficiencyAbsence of a serum proteinase inhibitor that may cause nodular non-suppurative panniculitis. ... (05 Mar 2000) ...
alpha-1,4-glucan lyase<enzyme> Degrades alpha-1,4-glucan to produce 1,5-anhydrofructose; from seaweeds gracilariopsis lemaneiformis and gracilaria verrucosa; mw 111 kD; amino acid sequence has been determined ... Registry number: EC 4.2.2.- ... Synonym: alpha-1,4-glucan 4-lyase ... (26 Jun 1999) ...
alpha-acetolactic acidAn intermediate in pyruvic acid catabolism and valine biosynthesis; CH3COC(OH)(CH3)-COOH. ... (05 Mar 2000) ...
alpha-actininAn F-actin binding protein in vertebrate cells that cross-links actin filaments into regular parallel arrays. ... (05 Mar 2000) ...
alpha-adrenergic blocking agentAn agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. ... Synonym: alpha-blocker. ... (05 Mar 2000) ...
alpha-adrenergic receptorsAdrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alph …
alpha-allocortol5alpha-Pregnane-3a,11b,17,20a,21-pentaol;the 5a enantiomer of alpha-cortol; a metabolite of hydroxycortisone found in the urine. ... (05 Mar 2000) ...
alpha-allocortolone3a,17,20a,21-Tetrahydroxy-5alpha-pregnane-11-one;the 5a enantiomer of alpha-cortolone; a metabolite of hydrocortisone found in urine. ... (05 Mar 2000) ...
alpha-allopregnanediol5alpha-Pregnane-3a,20alpha-diol;a metabolite of progesterone and adrenocortical hormones, found in urine. ... (05 Mar 2000) ...
alpha-amanitin<drug> A highly toxic, heat-stable bicyclic oligopeptide derived from the Amanita phalloides mushroom. It inhibits transcription by interfering with the function of certain RNA polymerases. ... (14 Aug 2000) ...
alpha-amino acidTypically, an amino acid of the general formula R-CHNH2-COOH (i.e., the NH2 in the a position); the l forms of these are the hydrolysis products of proteins. In rarer usages, this class of molecules also includes alpha-amino phosphoric acids and alpha-aminosulfonic acids. ... (05 Mar 2000) ...
alpha-amino acid esterase<enzyme> Converts alpha-amino acid esters and water to alpha-amino acids and alcohol ... Registry number: EC 3.1.1.43 ... Synonym: alpha-amino acid ester hydrolase ... (26 Jun 1999) ...
alpha-amino-beta-ketoadipic acid2-Amino-3-oxo-1,6-hexanedioic acid;an intermediate of porphobilinogen synthesis formed by d-aminolevulinic acid synthase from succinyl-CoA and glycine; it rapidly decarboxylates to d-aminolevulinic acid. ... (05 Mar 2000) ...
alpha-aminoacyl-peptide hydrolasesSynonym for aminopeptidases ... <enzyme> Registry number: EC 3.4.11. ... (12 Dec 1998) ...
alpha-aminoadipic acid2-amino-1,6-hexanedioic acid;an intermediate of lysine biosynthesis in higher fungi and bacteria, but not in algae and higher plants. Also in degradation of lysine in mammals. ... (05 Mar 2000) ...
alpha-aminoglutaric acidSynonym for glutamic acid ... <amino acid> One of the 20 _ amino acids commonly found in proteins. Plays a central role in amino acid metabolism, acting as precursor of glutamine, proline and arginine. Also acts as amino group donor in synthesis by transamination of alanine from pyruvate and aspartic acid from oxaloacetate. Glutamate is also a …
alpha-aminoisobutyric acid2-amino-2-methylpropionic acid;a synthetic amino acid useful in the study of amino acid transport across cell membranes and in the study of cytokine effects; it is not metabolised by the cell. ... (05 Mar 2000) ...
alpha-aminosuccinic acidSynonym for aspartic acid ... <amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 ... (09 Oct 1997) ...
alpha-amylase<enzyme> An enzyme that catalyses the endohydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides containing 3 or more 1,4-alpha-linked d-glucose units. ... Pharmacological action: anti-inflammatory agents. ... Chemical name: 1,4-alpha-D-Glucan glucanohydrolase ... Registry number: EC 3.2 …
alpha-antitrypsin deficiency<enzyme> A specific enzyme (alpha 1 antitrypsinase) that when absent genetically can result in panacinar emphysema (lung disease) and liver disease. ... There is no specific treatment for this condition other than supportive care for the liver and lung complications. ... Medications such as alpha-1proteinase inhibitor is given regularly to thes …
alpha-blockerSynonym for alpha-adrenergic blocking agent ... An agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. ... Synonym: alpha-blocker. ... (05 Mar 2000) ...
alpha-chloraloseA conjugate of chloral and glucose used as an anaesthetic in laboratory animals; it does not depress cardiovascular reflexes as much as most other anaesthetic agents. ... (05 Mar 2000) ...
alpha-chlorohydrin<chemical> 3-chloro-1,2-propanediol. A chlorinated propanediol compound that has shown anti-fertility activity in males and has been used as a chemosterilant in rodents. ... Pharmacological action: chemosterilants, contraceptive agents, male. ... Chemical name: 1,2-Propanediol, 3-chloro- ... (12 Dec 1998) ...
alpha-chymotrypsin-induced glaucomaTransient secondary glaucoma following the use of alpha-chymotrypsin in cataract extraction. ... (05 Mar 2000) ...
alpha-cortol5b-Pregnane-3a,11b,17,20a,21-pentaol; the 5b enantiomer of alpha-allocortol;a reduction product of cortisone, present in the urine, differing from cortisone in that the three keto groups are reduced to hydroxyls. ... (05 Mar 2000) ...
alpha-cortolone3a,17a,20a,21-Tetrahydroxy-5b-pregnane-11-one;the 5b enantiomer of alpha-allocortolone; a reduction product of cortisone, present in the urine, differing from cortisone in that two of the keto groups (at positions 3 and 20) are reduced to hydroxyls. ... (05 Mar 2000) ...
alpha-d-galactosidase<enzyme> An enzyme catalyzing the hydrolysis of alpha-d-galactosides to release free d-galactose. A deficiency of type A alpha-d-galactosidase is associated with Fabry's disease. ... Synonym: melibiase. ... (05 Mar 2000) ...
alpha-d-glucosidaseA glucohydrolase removing terminal nonreducing 1,4-linked alpha-glucose residues by hydrolysis, yielding alpha-glucose; a deficiency of the lysosomal enzyme is associated with glycogen storage disease type II. There are at least five isozymes of maltase. ... Synonym: glucoinvertase. ... (05 Mar 2000) ...
alpha-D-xylosidase<enzyme> Highly specific for 4-nitrophenyl alpha-d-xylopyranoside and isoprimeverose; can also split off the alpha-d-xylopyranosyl residue on the non-reducing terminal of the backbone of certain oligoxyloglucans ... Registry number: EC 3.2.1.- ... Synonym: alpha-d-xylosidase I, alpha-d-xylosidase II ... (26 Jun 1999) ...
alpha-endorphin<chemical> An endogenous opioid peptide derived from the pro-opiomelanocortin precursor. It differs from gamma-endorphin by one amino acid. ... Chemical name: alpha-Endorphin ... (12 Dec 1998) ...
alpha-farnesene3,7,11-Trimethyl-1,3,6,10-dodecatetraene;a straight open-chain hydrocarbon built up of three isoprene units; one of the four isomeric forms occurs in the natural coating of apples. ... (05 Mar 2000) ...
alpha-fetoprotein<protein, tumour marker> A protein substance that is normally produced by the liver cells. ... It is one of the first alpha-globulins to appear in mammalian sera during development of the embryo and the dominant serum proteins in early embryonic life. They reappear in the adult serum during certain pathologic states. ... Measurement of the alph …
alpha-fetoproteinsIncreases in maternal blood during pregnancy and, when detected by amniocentesis, is an important indicator of open neural tube defects and is also used as a tumour marker in adults with hepatocellular carcinoma, beta-fetoproteins, although a foetal liver protein, has been detected in adult patients with liver disease, gamma-fetoproteins occurs in …
alpha-fucosidase<enzyme> An enzyme that catalyses the hydrolysis of an an alpha-l-fucoside, producing an alcohol and l-fucose; a deficiency of the lysosomal enzyme will result in fucosidosis. ... (05 Mar 2000) ...
alpha-galactosidase<enzyme> An enzyme that catalyses the hydrolysis of terminal, non-reducing alpha-d-galactose residues in alpha-galactosides including galactose oligosaccharides, galactomannans, and galactolipids. ... Chemical name: alpha-D-Galactoside galactohydrolase ... Registry number: EC 3.2.1.22 ... (12 Dec 1998) ...
alpha-globulin<protein> The serum globulins with the most rapid electrophoretic migration, further subdivided into faster alpha(1)- and slower alpha(2)-globulins. ... (12 Dec 1998) ...
alpha-glucan phosphorylaseSynonym for phosphorylase ... <enzyme> Enzyme that catalyses the sequential removal of glycosyl residues from glycogen to yield one glucose-1-phosphate per reaction. Its activity is controlled by phosphorylation (by phosphorylase kinase). ... (21 Jun 2000) ...
alpha-glucosidases<enzyme> Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. ... Chemical name: alpha-D-Glucoside glucohydrolases ... Registry number: EC 3.2.1.20 ... (12 Dec 1998) ...
alpha-keto acid dehydrogenaseSee: alpha-keto acid dehydrogenase. ... Anaerobic dehydrogenase, an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule (e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenase's, isocitrate dehydrogenase's, and others in EC class 1, excluding those listed under aerobic …
alpha-ketoadipate dehydrogenase<enzyme> X-ketoadipic acid + nad + CoA yields glutaryl-CoA + co(2) + NADH + h ... Registry number: EC 1.2.1.- ... (26 Jun 1999) ...
alpha-ketoarginine decarboxylase<enzyme> Alpha-ketoarginine gives gamma-guanidinobutyraldehyde ... Registry number: EC 4.1.1.- ... Synonym: alpha keto-arginine decarboxylase ... (26 Jun 1999) ...
alpha-ketobutyrate dehydrogenase<enzyme> Rat liver enzyme oxidatively decarboxylates alpha-ketobutyrate to carbon dioxide and propionyl CoA; requires nad, fad and thiamine pyrophosphate ... Registry number: EC 1.2.1.- ... (26 Jun 1999) ...
alpha-ketodecarboxylaseFormerly, the enzyme system converting pyruvate (a 2-oxoacid) to acetyl-CoA and CO2, with reduction of NAD+ to NADH and the participation of lipoamide and thiamin pyrophosphate; now known to involve at least three enzymes in succession: pyruvate dehydrogenase, dihydrolipoamide acetyltransferase, and dihydrolipoamide dehydrogenase. ... Compare: pyruv …
alpha-ketoglutaramic acidH2N-COCH2CH2COCOOH;a metabolite of glutamine formed by the action of glutamine aminotransferase; elevated in certain cases of hepatocoma. ... Synonym: 2-oxoglutaric acid. ... (05 Mar 2000) ...
alpha-ketoglutarateA salt or ester of alpha-ketoglutaric acid. ... Alpha-ketoglutarate dehydrogenase, an enzyme that catalyses the oxidative decarboxylation of 2-ketoglutaric acid to succinyldihydrolipoate; the succinyl group is later transferred to CoA and the reduced lipoate is oxidised by NAD+; a complex that is a part of the tricarboxylic acid cycle. ... Synonym: 2 …
alpha-ketoglutarate permease<chemical> From E coli; 432-amino acid protein; amino acid sequence given in first source ... Synonym: kGTP gene product, wita protein, alpha-ketoglutarate transporter ... (26 Jun 1999) ...
alpha-ketoisocaproate oxygenase<enzyme> From rat liver cytosol; oxidatively decarboxylates and hydroxylates alpha-ketoisocaporate to form beta-hydroxyisovalerate; requires fe(2+) and thiol; activated by ascorbate ... Registry number: EC 1.13.11.- ... Synonym: 2-ketoisocaproate oxygenase, alpha-ketoisocaproate dioxygenase ... (26 Jun 1999) ...
alpha-ketosuccinamic acidNH2-CO-CH2-CO-COOH;the transamination product of asparagine; acted upon by ω-amidase. ... (05 Mar 2000) ...
alpha-l-iduronidase<enzyme> An enzyme that hydrolyzes terminal desulfated alpha-l-iduronic acid residues of dermatan sulfate and of heparan sulfate; a deficiency of this enzyme is associated with Hurler syndrome and Scheie syndrome. ... (05 Mar 2000) ...
alpha-lactyl-thiamin pyrophosphateSynonym for active pyruvate ... An intermediate formed in the oxidative decarboxylation of pyruvate. ... Compare: pyruvate dehydrogenase (lipoamide). ... Synonym: alpha-lactyl-thiamin pyrophosphate. ... (05 Mar 2000) ...
alpha-linolenic acid<chemical> (z,z,z)-9,12,15-octadecatrienoic acid. A fatty acid that is found in plants and involved in the formation of prostaglandins. ... Chemical name: 9,12,15-Octadecatrienoic acid, (Z,Z,Z)- ... (12 Dec 1998) ...
alpha-macroglobulinsGlycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters. ... (12 Dec 1998) ...
alpha-mannosidase<enzyme> Catalyses hydrolysis of terminal, non-reducing alpha-d-mannose residues in alpha-d-mannosides ... Registry number: EC 3.2.1.24 ... Synonym: alpha-d-mannoside mannohydrolase, alpha-d-mannosidase, neutral alpha-mannosidase, alpha mannosidase a, alpha mannosidase b, lysosomal alpha-mannosidase, laman ... (26 Jun 1999) ...
alpha-methylacyl-CoA racemase<enzyme> Involved in catabolism of branched-chain fatty acids derived from isoprenoids; acts on pristanoyl-CoA and trihydroxycoprostanoyl-CoA, but not on 3-methyl branched-chain or linear-chain acyl coas; amino acid sequence has been determined; genbank u89905 (rat) and u89906 (mouse); also isolated from human liver ... Registry number: EC 5.1 …
alpha-methyltyrosine<chemical> An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma and decreases the frequency and severity of hypertensive attacks and related symptoms in most patients. (martindale, the …
alpha-msh<chemical> A 13-amino acid peptide derived from the anterior pituitary gland in man and from the pars intermedia in lower vertebrates. Its amino acid sequence is identical to the first 13 amino acids of acth. It influences the formation of deposition of melanin in the body and produces colour changes in the skin of amphibians, fishes and rept …
alpha-N-acetyl-D-glucosaminidase<enzyme> Believed to be deficient in sanfilippo syndrome type b ... Registry number: EC 3.2.1.50 ... Synonym: alpha-n-acetylglucosaminidase ... (26 Jun 1999) ...
alpha-N-acetylgalactosaminidase<enzyme> An enzyme that hydrolyzes 2-acetamido-2-deoxy-alpha-d-galactosides to the alcohol and free 2-acetamido-2-deoxy-d-galactose. A deficiency of this enzyme will result in Schindler disease. ... (05 Mar 2000) ...
alpha-N-acetylglucosaminidase<enzyme> An enzyme that hydrolyzes glycosides of N-acetylglucosamine producing the alcohol and N-acetylglucosamine. A deficiency of this enzyme results in mucopolysaccharidosis III B. ... (05 Mar 2000) ...
alpha-N-acylamino acid hydrolase<enzyme> Functions in catabolism of n-acetylamino acids resulting from turnover of alpha-n-acetylated proteins ... Registry number: EC 3.5.1.- ... Synonym: alpha-n-acetylamino acid hydrolase, anaa-hase, n-acylaminoacyl-peptide hydrolase ... (26 Jun 1999) ...
alpha-naphthylthiourea1-(1-Naphthyl)-2-thiourea;a derivative of thiourea; a highly toxic antithyroid agent, especially to small mammals, causing pulmonary oedema, fatty degeneration of the liver, and low body temperature; used as a rat poison. ... Acronym: ANTU ... (05 Mar 2000) ...
alpha-oxidationA form of oxidation of fatty acids in which carbons are removed one at a time in the form of CO2; the alpha-carbon is first hydroxylated and then converted into a carbonyl; a deficiency of this pathway is associated with Refsum's disease. ... (05 Mar 2000) ...
alpha-pinene oxide lyase<enzyme> From nocardia sp. Strain p18.3; catalyses the cleavage of both rings of the bicyclic structure with the formation of 2-methyl-5-isopropylhexa-2,5-dienal ... Registry number: EC 4.1.2.- ... Synonym: alpha-pinene oxide lyase (decyclizing) ... (26 Jun 1999) ...
