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 mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


lymphoadenoma
1. Obsolete term for an enlarged lymph node. ... 2. Obsolete term for Hodgkin's disease. ... (05 Mar 2000) ...

lymphoblast
<haematology> Often referred to as a blast cell. Unlike other usages of the suffix blast a lymphoblast is a further differentiation of a lymphocyte, T or B, occasioned by an antigenic stimulus. The lymphoblast usually develops by enlargement of a lymphocyte, active re entry to the S phase of the cell cycle, mitogenesis and production of much …

lymphoblastic
Pertaining to the production of lymphocytes. ... (05 Mar 2000) ...

lymphoblastic leukaemia
Acute lymphocytic leukaemia in which the abnormal cells are chiefly (or almost totally) blast forms of the lymphocytic series, or in which unusually large numbers of the immature forms occur in association with adult lymphocytes. ... (05 Mar 2000) ...

lymphoblastic lymphoma
<tumour> A diffuse lymphoma in children, with supradiaphragmatic distribution and T lymphocytes having convoluted nuclei; many patients develop acute lymphoblastic leukaemia. ... (05 Mar 2000) ...

lymphoblastoma
<tumour> A form of malignant lymphoma in which the chief cells are lymphoblasts. ... Origin: Lymphoblast + G. -oma, tumour ... (05 Mar 2000) ...

lymphoblastosis
The presence of lymphoblasts in the peripheral blood; sometimes used as a synonym for acute lymphocytic leukaemia. ... Origin: Lymphoblast + G. -osis, condition ... (05 Mar 2000) ...

lymphocele
Cystic mass containing lymph from diseased lymphatic channels or following surgical trauma or other injury. ... (12 Dec 1998) ...

lymphocerastism
The process of formation of cells in the lymphocytic series. ... Origin: Lympho-+ G. Kerastos, mixed, mingled ... (05 Mar 2000) ...

lymphocinesis
Synonym for lymphokinesis ... 1. Circulation of lymph in the lymphatic vessels and through the lymph nodes. ... 2. Movement of endolymph in the semicircular canals of the inner ear. ... Synonym: lymphocinesis, lymphocinesia. ... Origin: Lympho-+ G. Kinesis, movement ... (05 Mar 2000) ...

lymphocryptovirus
A genus of the family herpesviridae, subfamily gammaherpesvirinae, consisting of viruses similar to the type species human herpes virus 4 (herpes virus 4, human), better known as the epstein-barr virus. ... (12 Dec 1998) ...

lymphocyst
Synonym: lymphocele. ... Origin: Lympho-+ G. Kystis, bladder ... (05 Mar 2000) ...

lymphocytapheresis
Separation and removal of lymphocytes from the withdrawn blood, with the remainder of the blood retransfused into the donor. ... Synonym: lymphapheresis. ... Origin: Lymphocyte + G. Aphairesis, a withdrawal ... (05 Mar 2000) ...

lymphocyte
<haematology> White cell of the blood that are derived from stem cells of the lymphoid series. ... Two main classes are recognised, T and B lymphocytes, the latter responsible (when activated) for production of antibody, the former subdivided into subsets (helper, suppressor, cytotoxic T-cells) and responsible both for cell-mediated immunity a …

lymphocyte activation
<haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associ …

lymphocyte cooperation
T-cell enhancement of the B-cell response to thymic-dependent antigens. ... (12 Dec 1998) ...

lymphocyte count
A count of the number of lymphocytes in the blood. ... (12 Dec 1998) ...

lymphocyte depletion
Immunosuppression by reduction of circulating lymphocytes or by T-cell depletion of bone marrow. The former may be accomplished in vivo by thoracic duct drainage or administration of antilymphocyte serum. The latter is performed ex vivo on bone marrow before its transplantation. ... (12 Dec 1998) ...

lymphocyte lymphocyte
A type of non-granular antibodies. ... (09 Oct 1997) ...

lymphocyte subsets
A classification of lymphocytes based on structurally or functionally different populations of cells. ... (12 Dec 1998) ...

lymphocyte transformation
Synonym for lymphocyte activation ... <haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused w …

lymphocyte transfusion
The transfer of lymphocytes from a donor to a recipient or reinfusion to the donor. ... (12 Dec 1998) ...

lymphocyte-oriented kinase
<enzyme> An ste20-like protein kinase; genbank d89728 ... Registry number: EC 2.7.10.- ... Synonym: lok gene product ... (26 Jun 1999) ...

lymphocytes
White blood cells that fight infection and disease. ... (12 Dec 1998) ...

lymphocytes, null
A class of lymphocytes characterised by the lack of surface markers specific for either t or b lymphocytes. ... (12 Dec 1998) ...

lymphocytes, tumour-infiltrating
Lymphocytes that show specificity for autologous tumour cells. Ex vivo isolation and culturing of til with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer. ... (12 Dec 1998) ...

lymphocythemia
Synonym for lymphocytosis ... A condition in which the blood contains an unusually high number of normal lymphocytes. ... (09 Oct 1997) ...

lymphocytic
<haematology> Pertaining to, characterised by or of the nature of lymphocytes. ... (18 Nov 1997) ...

lymphocytic adenohypophysitis
A diffuse lymphocytic infiltration of the adenohypophysis, often related to pregnancy; probably a disturbance in the immune system. ... (05 Mar 2000) ...

lymphocytic choriomeningitis
A form of viral meningitis caused by the lymphocytic choriomeningitis virus. In humans it may be inapparent or present with symptoms of a flu-like disease, aseptic meningitis, encephalitis, or myelitis. ... (12 Dec 1998) ...

lymphocytic choriomeningitis virus
The type species of arenavirus, part of the lcm-lassa complex viruses, producing an inapparent infection in house and laboratory mice. In humans, infection with lcmv can be inapparent, or can present with an influenza-like illness, a benign aseptic meningitis, or a severe meningoencephalomyelitis. The virus can also infect monkeys, dogs, field mice …

lymphocytic interstitial pneumonia
Synonym for lymphocytic interstitial pneumonitis ... A rare disease characterised by interstitial accumulation of lymphocytes in the lungs and late fibrosis; usually a result of a lymphoma, occasionally seen in AIDS, especially. In children. Sometimes seen as an autoimmune disorder. ... Synonym: lymphocytic interstitial pneumonia, lymphoid interstiti …

lymphocytic leukaemia
<haematology, oncology> An acute form of childhood leukaemia characterised by the development of abnormal cellsdevelop in the bone marrow and lymphoblasts are found in blood-formingtissues. ... A type of chronic leukaemia found most often in the elderly, it is characterised by the presence of mature lymphocytes in the blood. ... Origin: Gr. Hai …

lymphocytic leukemoid reaction
Leukocytosis of varying degree, with adult lymphocytes and immature forms amounting to 40% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with pertussis, infectious mononucleosis, gonorrhoea, chickenpox, and sarcoidosis. ... (05 Mar 2000) ...

lymphocytic leukocytosis
Synonym for lymphocytosis ... A condition in which the blood contains an unusually high number of normal lymphocytes. ... (09 Oct 1997) ...

lymphocytic leukopenia
Synonym for lymphopenia ... Reduction in the number of lymphocytes. ... (12 Dec 1998) ...

lymphocytic lymphoma
<oncology, tumour> A cancer of lymphatic tissues, the tumour cells are mostly abnormal lymphocytes. ... (13 Nov 1997) ...

lymphocytic thyroiditis
Synonym for Hashimoto's thyroiditis ... <endocrinology> Inflammation of the thyroid gland without the formation of pus. Noninfectious nonbacterial thyroid inflammation. ... (27 Sep 1997) ...

lymphocytoblast
Synonym: lymphoblast. ... Origin: Lymphocyte + G. Blastos, germ ... (05 Mar 2000) ...

lymphocytoma
<oncology, tumour> A mass of mature lymphocytes which at first glance resembles a tumour. ... (09 Oct 1997) ...

lymphocytopenia
A condition in which the blood contains an abnormally low number of lymphocytes. ... (09 Oct 1997) ...

lymphocytopoiesis
The formation of lymphocytes. ... Origin: Lymphocyte + G. Poiesis, a making ... (05 Mar 2000) ...

lymphocytosis
A condition in which the blood contains an unusually high number of normal lymphocytes. ... (09 Oct 1997) ...

lymphocytotoxic antibodies
Antibody's specific for histocompatibility antigens of lymphocytes and which, upon combining with the antigens, induce cellular damage or death. ... (05 Mar 2000) ...

lymphoderma
A condition resulting from any disease of the cutaneous lymphatic vessels. ... Origin: Lympho-+ G. Derma, skin ... (05 Mar 2000) ...

lymphoduct
A lymphatic vessel. ... See: lymph vessels. ... Origin: Lympho-+ L. Ductus, a leading ... (05 Mar 2000) ...

lymphoedema
<dermatology, oncology> Swelling of the subcutaneous tissues caused by obstruction of the lymphatic drainage. ... It results from fluid accumulation and may arise from surgery, radiation or the presence of a tumour in the area of the lymph nodes. ... (14 Oct 1997) ...

lymphoepithelial cyst
A cervical cyst arising from salivary gland epithelium entrapped in lymph nodes during embryogenesis. Also seen within the oral cavity. ... (05 Mar 2000) ...

lymphoepithelioma
<tumour> A poorly differentiated radiosensitive squamous cell carcinoma involving lymphoid tissue in the region of the tonsils and nasopharynx; composed of irregular sheets, or small groups, of neoplastic epithelial cells (squamous or undifferentiated), with a slight to moderate amount of fibrous stroma that contains numerous lymphocytes; met …

lymphogenesis
Lymph production. ... Origin: Lympho-+ G. Genesis, production ... (05 Mar 2000) ...

lymphogenous
1. Originating from lymph or the lymphatic system. ... Synonym: lymphogenic. ... 2. Producing lymph. ... (05 Mar 2000) ...

lymphogenous metastasis
See: metastasis. ... (05 Mar 2000) ...

lymphoglandula
Synonym for lymph node ... <anatomy> Small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells located along the lymphatic system. ... Recirculating lymphocytes leave the blood through the specialised high endothelial venules of the lymph node and …

lymphogranuloma
1. Old non-specific term used with reference to a few basically dissimilar diseases in which the pathologic processes result in granulomas or granuloma-like lesions, especially in various groups of lymph nodes (which then become conspicuously enlarged). ... 2. Old term for Hodgkin's disease. ... (05 Mar 2000) ...

lymphogranuloma benignum
Old term for sarcoidosis. ... (05 Mar 2000) ...

lymphogranuloma inguinale
Synonym for venereal lymphogranuloma ... A venereal infection usually caused by Chlamydia trachomatis, and characterised by a transient genital ulcer and inguinal adenopathy in the male; in the female, perirectal lymph nodes are involved and rectal stricture is a common occurrence. ... Synonym: climatic bubo, Favre-Durand-Nicholas disease, lymphogran …

lymphogranuloma malignum
Old term for Hodgkin's disease. ... (05 Mar 2000) ...

lymphogranuloma venereum
<gynaecology> A sexually transmitted bacterial disease that is caused by the micro-organism Chlamydia trachomatis. ... Symptoms usually begin 1-3 weeks after contact. Symptoms include lymph node swelling in the groin, fever, headache, chills and skin ulcers (or bumps) on the genitalia. ... (27 Sep 1997) ...

lymphogranuloma venereum antigen
A sterile preparation of inactivated chlamydiae grown in the yolk sac of domestic fowl and used as an antigen in the Frei test. ... (05 Mar 2000) ...

lymphogranuloma venereum virus
Former name for Chlamydia trachomatis. ... (05 Mar 2000) ...

lymphogranulomatosis
Any condition characterised by the occurrence of multiple and widely distributed lymphogranulomas. ... (05 Mar 2000) ...

lymphohistiocytic
Involving lymphocytes and histiocytes. ... (16 Dec 1997) ...

lymphohistiocytosis
Proliferation or infiltration of lymphocytes and histiocytes. ... (05 Mar 2000) ...

lymphoid
Composed of lymphatic tissue. ... (27 Sep 1997) ...

lymphoid cell
<haematology, pathology> Cells derived from stem cells of the lymphoid lineage: large and small lymphocytes, plasma cells. ... (18 Nov 1997) ...

lymphoid haemoblast of Pappenheim
Synonym for pronormoblast ... The earliest of four stages in development of the normoblast. ... See: erythroblast. ... Synonym: lymphoid haemoblast of Pappenheim, proerythroblast, rubriblast. ... (05 Mar 2000) ...

lymphoid hypophysitis
lymphocytic hypophysitis ...

lymphoid interstitial pneumonia
Synonym for lymphocytic interstitial pneumonitis ... A rare disease characterised by interstitial accumulation of lymphocytes in the lungs and late fibrosis; usually a result of a lymphoma, occasionally seen in AIDS, especially. In children. Sometimes seen as an autoimmune disorder. ... Synonym: lymphocytic interstitial pneumonia, lymphoid interstiti …

lymphoid interstitial pneumonitis
<pathology> A form of pneumonia which is characterised by diffuse interstitial infiltrates and infiltration of lymphocytes into the lung tissue. ... (27 Sep 1997) ...

lymphoid leukaemia
Synonym for lymphocytic leukaemia ... <haematology, oncology> An acute form of childhood leukaemia characterised by the development of abnormal cellsdevelop in the bone marrow and lymphoblasts are found in blood-formingtissues. ... A type of chronic leukaemia found most often in the elderly, it is characterised by the presence of mature lymphoc …

lymphoid polyp
Benign polyp consisting of aggregates of lymphocytes in the rectum. ... (05 Mar 2000) ...

lymphoid ring
The broken ring of lymphoid tissue, formed of the lingual, faucial, and pharyngeal tonsils. ... Synonym: Bickel's ring, tonsillar ring, Waldeyer's throat ring. ... (05 Mar 2000) ...

lymphoid series
The cells at various states in the development in lymphoid tissue of the mature lymphocytes, e.g., lymphoblasts, young lymphocytes, mature lymphocytes. ... (05 Mar 2000) ...

lymphoid tissue
<anatomy> Tissue that is particularly rich in lymphocytes (and accessory cells such as macrophages and reticular cells), particularly the lymph nodes, spleen, thymus, Peyer's patches, pharyngeal tonsils, adenoids and (in birds) the Bursa of Fabricius. ... Central lymphoid tissue: A term occasionally used as synonym for primary lymphoid tissue …

lymphoidectomy
<procedure> Excision of lymphoid tissue. ... Origin: Lymphoid + G. Ektome, excision ... (05 Mar 2000) ...

lymphoidocyte
A primitive mesenchymal cell believed to be capable of differentiating into all types of lymphoid cells, including lymphocytes, littoral cells, and reticular cells of lymph nodes. ... (05 Mar 2000) ...

lymphokine
<growth factor> Substance produced by a leucocyte that acts upon another cell. ... Examples are interleukins, interferon alpha, lymphotoxin (tumour necrosis factor alpha), granulocyte monocyte colony-stimulating factor (GM-CSF). The term is becoming less common and cytokine, a more general term, is taking over. Cytokines include lymphokines.
lymphokines
Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those involved in cellular immunity. ... (12 Dec 1998) ...

lymphokinesis
1. Circulation of lymph in the lymphatic vessels and through the lymph nodes. ... 2. Movement of endolymph in the semicircular canals of the inner ear. ... Synonym: lymphocinesis, lymphocinesia. ... Origin: Lympho-+ G. Kinesis, movement ... (05 Mar 2000) ...

lympholeukocyte
Synonym for lymphocyte ... <haematology> White cell of the blood that are derived from stem cells of the lymphoid series. ... Two main classes are recognised, T and B lymphocytes, the latter responsible (when activated) for production of antibody, the former subdivided into subsets (helper, suppressor, cytotoxic T-cells) and responsible both fo …

lymphology
Synonym: lymphangiology. ... Origin: Lympho-+ G. Logos, study ... (05 Mar 2000) ...

lymphoma
<oncology, tumour> Malignant tumour of lymphoblasts derived from B lymphocytes. most commonly affects children in tropical Africa: both Epstein Barr virus and immunosuppression due to malarial infection are involved. ... (18 Nov 1997) ...

lymphoma, aids-related
B-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromos …

lymphoma, B-cell
A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. ... (12 Dec 1998) ...

lymphoma, diffuse
Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. ... (12 Dec 1998) ...

lymphoma, follicular
Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centres of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular centre B-lymphocytes. This class of lymphoma usually occurs in older p …

lymphoma, high-grade
One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential. ... (12 Dec 1998) ...

lymphoma, intermediate-grade
One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have an intermediate survival potential. ... (12 Dec 1998) ...

lymphoma, large-cell
A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter …

lymphoma, large-cell, diffuse
Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. ... (12 Dec 1998) ...

lymphoma, large-cell, follicular
Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. ... (12 Dec 1998) ...

lymphoma, large-cell, immunoblastic
Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymp …

lymphoma, large-cell, ki-1
A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. ... (12 Dec 1998)< …

lymphoma, low-grade
One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. ... (12 Dec 1998) ...

lymphoma, lymphoblastic
A high-grade malignant lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm. The cells are cytologically similar to the lymphoblasts seen in acute lymphocytic leukaemia, and in some cases, the disease may evolve into a leukaemic phase morphologically indistinguishable from ac …

lymphoma, mixed-cell
Malignant lymphoma characterised by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. ... (12 Dec 1998) ...

lymphoma, mixed-cell, diffuse
A heterogeneous group of intermediate-grade lymphomas of mixed cellular composition. Although they have not been extensively studied, it appears that they are predominantly B-cell diseases. ... (12 Dec 1998) ...

lymphoma, mixed-cell, follicular
A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. ... (12 Dec 1998) ...

lymphoma, non-hodgkin
Any of a group of malignant tumours of lymphoid tissue that differ from hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumours is the absence of giant reed-sternberg cells, a characteristic of hodgkin's disease. ... (12 Dec 1998) ...

lymphoma, small lymphocytic
A low-grade malignant lymphoma that may, in some cases, be considered histologically identical to chronic lymphocytic leukaemia (cll; leukaemia, lymphocytic, chronic). It is diffuse in pattern, representing the neoplastic proliferation of well-differentiated B-lymphocytes. In patients with immunoglobulin gammopathies, the lymphocytes may exhibit pl …