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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

lymphoma, small noncleaved-cell
A high-grade malignant lymphoma that includes both burkitt tumour (burkitt lymphoma) and other lymphomas previously designated undifferentiated non-burkitt type. Nuclei in burkitt tumour are round to ovoid and uniform in size. The non-burkitt type exhibits greater nuclear variation and less evidence of cellular maturation with a correspondingly les …

lymphoma, small-cell
A B-cell lymphoma presumably representing a tumour of interfollicular B-lymphocytes that may be functional. Those that are secrete identical immunoglobulin molecules. ... (12 Dec 1998) ...

lymphoma, T-cell
A group of heterogeneous lymphoid tumours representing malignant transformations of T-lymphocytes. ... (12 Dec 1998) ...

lymphoma, T-cell, cutaneous
A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. Mycosis fungoides and sezary syndrome are the best characterised of these disorders. ... (12 Dec 1998) ...

lymphoma, T-cell, peripheral
A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymp …

lymphoma, undifferentiated
A form of lymphoma in which relatively large stem cells with large nuclei, pale, scanty cytoplasm, and indistinct borders are predominant. The cells are undifferentiated, i.e., show no morphologic evidence of maturation toward lymphocytes or histiocytes. ... (12 Dec 1998) ...

lymphomatoid
Resembling a lymphoma. ... (05 Mar 2000) ...

lymphomatoid granulomatosis
An angiocentric and angiodestructive lymphoreticular proliferative disorder primarily involving the lungs. Histologically it simulates malignant lymphoma and in some cases may progress to lymphoma. ... (12 Dec 1998) ...

lymphomatoid papulosis
Clinically benign, histologically malignant, recurrent cutaneous eruption characterised by an infiltration of large atypical cells surrounded by inflammatory cells. The atypical cells resemble reed-sternberg cells of hodgkin's disease or the malignant cells of cutaneous T-cell lymphoma. In some cases, lymphomatoid papulosis progresses to lymphomato …

lymphomatosis
Any condition characterised by the occurrence of multiple, widely distributed sites of involvement with lymphoma. ... Avian lymphomatosis, a group of virus-induced transmissible diseases of chickens and some other birds in which there is lymphoid cell infiltration or formation of lymphomatous tumours in various tissues and organs; the two principal …

lymphomatous
Pertaining to or characterised by lymphoma. ... (05 Mar 2000) ...

lymphomyeloma
<tumour> A medullary neoplasm that consists of uninuclear, relatively small cells with morphologic features resembling those of lymphocytic forms. ... Origin: Lympho-+ G. Myelos, marrow, + -oma, tumour ... (05 Mar 2000) ...

lymphomyxoma
<tumour> A soft nonmalignant neoplasm that contains lymphoid tissue in a matrix of loose, areolar connective tissue. ... Origin: Lympho-+ G. Myxa, mucus, + -oma, tumour ... (05 Mar 2000) ...

lymphopathia
Synonym for lymphopathy ... Any disease of the lymphatic vessels or lymph nodes. ... Synonym: lymphopathia. ... Origin: Lympho-+ G. Pathos, suffering ... (05 Mar 2000) ...

lymphopathia venereum
An obsolete term for lymphogranuloma venereum. ... (05 Mar 2000) ...

lymphopathy
Any disease of the lymphatic vessels or lymph nodes. ... Synonym: lymphopathia. ... Origin: Lympho-+ G. Pathos, suffering ... (05 Mar 2000) ...

lymphopenia
Reduction in the number of lymphocytes. ... (12 Dec 1998) ...

lymphopenic thymic dysplasia
An obsolete term for thymic alymphoplasia. ... (05 Mar 2000) ...

lymphoplasmapheresis
Separation and removal of lymphocytes and plasma from the withdrawn blood, with the remainder of the blood retransfused into the donor. ... Origin: Lymphocyte + plasma + G. Aphairesis, a withdrawal ... (05 Mar 2000) ...

lymphoplasty
Synonym for lymphangioplasty ... Surgical alteration of lymphatic vessels. ... Synonym: lymphoplasty. ... Origin: Lymphangio-+ G. Plastos, formed ... (05 Mar 2000) ...

lymphopoiesis
The formation of lymphatic tissue. ... Origin: Lympho-+ G. Poiesis, a making ... (05 Mar 2000) ...

lymphopoietic
Pertaining to or characterised by lymphopoiesis. ... (05 Mar 2000) ...

lymphoproliferation
<haematology, pathology> An increase in the production of lymphocytes. This may occur as a normal response to infection. ... (20 Mar 1998) ...

lymphoproliferative disorders
Disorders characterised by proliferation of lymphoid tissue, general or unspecified. ... (12 Dec 1998) ...

lymphoproliferative response
<haematology, immunology> A specific immune response that entails rapid T-cell replication. Standard antigens, such as tetanus toxoid, that elicit this response are used in lab tests of immune competence. ... (13 Nov 1997) ...

lymphoreticulosis
Proliferation of the reticuloendothelial cells (macrophages) of the lymph glands. ... (05 Mar 2000) ...

lymphorrhagia
Synonym: lymphorrhoea. ... Origin: Lympho-+ G. Rhegnymi, to burst forth ... (05 Mar 2000) ...

lymphorrhoea
An escape of lymph on the surface from ruptured, torn, or cut lymphatic vessels. ... Synonym: lymphorrhagia. ... Origin: Lympho-+ G. Rhoia, a flow ... (05 Mar 2000) ...

lymphorrhoid
A dilation of a lymph channel, resembling a haemorrhoid. ... Origin: Lymh + -rrhoid, tending to leak, on the analogy of haemorrhoid ... (05 Mar 2000) ...

lymphosarcoma
<tumour> Obsolete term for malignant lymphoma. ... Origin: Lympho-+ G. Sarkoma, sarcoma ... Bovine lymphosarcoma, a systemic malignancy of the lymphoreticular system of cattle which is seen in two aetiologically and clinically distinct forms, enzootic bovine leukosis and sporadic bovine leukosis. ... (05 Mar 2000) ...

lymphosarcomatosis
An obsolete term for a condition characterised by the presence of multiple, widely distributed masses of lymphosarcoma. ... (05 Mar 2000) ...

lymphoscintigraphy
Scintillation scanning of lymphatics or lymph nodes following intralymphatic or subcutaneous injection of a radionuclide. ... (05 Mar 2000) ...

lymphosis
Rarely used term for lymphocytic leukaemia. ... (05 Mar 2000) ...

lymphostasis
Obstruction of the normal flow of lymph. ... Origin: Lympho-+ G. Stasis, a standing still ... (05 Mar 2000) ...

lymphostatic verrucosis
Synonym for mossy foot ... A profuse velvety papillomatous growth that develops large warty projections; caused by chronic lymphedema and stasis with maceration and associated infection. ... Synonym: lymphedematous keratoderma, lymphostatic verrucosis. ... (05 Mar 2000) ...

lymphotaxis
The exertion of an effect that attracts or repels lymphocytes. ... Origin: Lympho-+ G. Taxis, orderly arrangement ... (05 Mar 2000) ...

lymphotoxicity
Toxicity to lymphocytes. ... (05 Mar 2000) ...

lymphotoxin
<growth factor> Cytotoxic product of T-cells. ... Synonym: tumour necrosis factor alpha. ... (18 Nov 1997) ...

lymphotrophy
Nourishment of the tissues by lymph in parts devoid of blood vessels. ... Origin: Lympho-+ G. Trophe, nourishment ... (05 Mar 2000) ...

lymphuria
Discharge of lymph in the urine. ... Origin: Lympho-+ G. Ouron, urine ... (05 Mar 2000) ...

lyn
<molecular biology> Gene encoding a nonreceptor tyrosine kinase, related to src. ... (18 Nov 1997) ...

lynestrenol
<chemical> (17 alpha)-19-norpregn-4-en-20-yn-17-ol. A synthetic progestational hormone used often in mixtures with oestrogens as an oral contraceptive. ... Pharmacological action: contraceptives, oral, synthetic, progestational hormones, synthetic. ... Chemical name: 19-Norpregn-4-en-20-yn-17-ol, (17alpha)- ... (12 Dec 1998) ...

lyngbya toxins
Toxins isolated from any species of the seaweed lyngbya or similar chemicals from other sources, including mollusks and micro-organisms. These have been found to be potent tumour promoters. ... (12 Dec 1998) ...

lynx
1. <zoology> Any one of several species of feline animals of the genus Felis, and subgenus Lynx. They have a short tail, and usually a pencil of hair on the tip of the ears. ... Among the well-known species are the European lynx (Felis borealis); the Canada lynx or loup-cervier (F. Canadensis); the bay lynx of America (F. Rufa), and its wester …

lyo-
Dissolution. ... See: lyso-. ... Origin: G. Lyo, to loosen, dissolve ... (05 Mar 2000) ...

lyoenzyme
Synonym for extracellular enzyme ... <enzyme> An enzyme performing its functions outside a cell; e.g., the various digestive enzyme's. ... Synonym: exoenzyme, lyoenzyme. ... (05 Mar 2000) ...

lyolysis
Rarely used term for solvolysis. ... (05 Mar 2000) ...

Lyon hypothesis
<genetics> Hypothesis, first advanced by Lyon, concerning the random inactivation of one of the two X chromosomes of the cells of female mammals. ... In consequence females are chimaeric for the products of the X chromosomes, a situation that has been exploited in female Negroes (who are heterotypic for isozymes of glucose 6 phosphate dehydrog …

Lyon, B
<person> Vincent, U.S. Physician, 1880-1953. ... See: Meltzer-Lyon test. ... (05 Mar 2000) ...

Lyon, Mary
<person> English cytogeneticist, *1925. ... See: Lyon hypothesis, lyonization. ... (05 Mar 2000) ...

Lyonisation
Synonym for Lyon hypothesis ... <genetics> Hypothesis, first advanced by Lyon, concerning the random inactivation of one of the two X chromosomes of the cells of female mammals. ... In consequence females are chimaeric for the products of the X chromosomes, a situation that has been exploited in female Negroes (who are heterotypic for isozymes …

lyonization
The inactivation of an X chromosome. One of the two x chromosomes in every cell in a female is randomly inactivated early in embryonic development. Named after geneticist mary lyon. ... (12 Dec 1998) ...

lyophil
Lyophile ... A substance that is lyophilic. ... (05 Mar 2000) ...

lyophilic
<chemistry> Characteristic of a material that readily forms a colloidal suspension. Molecules of the solvent form a shell around the particles, if the solvent is water then hydrophilic. ... (20 Mar 1998) ...

lyophilic colloid
Synonym for emulsoid ... A colloidal dispersion in which the dispersed particles are more or less liquid and exert a certain attraction on and absorb a certain quantity of the fluid in which they are suspended. ... Synonym: emulsion colloid, hydrophil colloid, hydrophilic colloid, lyophilic colloid. ... (05 Mar 2000) ...

lyophilisate
<biochemistry> The product of lyophilisation (the creation of a stable preparation of a biological substance, such as blood plasma or serum, by rapid freezing and dehydration of the frozen product under high vacuum). ... (20 Mar 1998) ...

lyophilization
The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum. ... Synonym: freeze-drying. ... (05 Mar 2000) ...

lyophobe
A substance that is lyophobic. ... (05 Mar 2000) ...

lyophobic
In colloid chemistry, denoting a dispersed phase having but slight affinity for the dispersion medium; when the dispersed phase is lyophobic, the colloid is usually an irreversible one. ... Origin: Lyo-+ G. Phobos, fear ... (05 Mar 2000) ...

lyophobic colloid
Synonym for suspensoid ... A colloidal solution in which the disperse particles are solid and lyophobe or hydrophobe, and are therefore sharply demarcated from the fluid in which they are suspended. ... Synonym: hydrophobic colloid, lyophobic colloid, suspension colloid. ... Origin: suspension + G. Eidos, resemblance ... (05 Mar 2000) ...

lyosorption
Adsorption of a liquid on a solid surface. ... (05 Mar 2000) ...

lyotropic
Synonym: lyophilic. ... Origin: Lyo-+ G. Trope, a turning ... (05 Mar 2000) ...

lyotropic series
<chemistry> A listing of anions and cations in order of their effect on protein solubility (tendency to cause salting out). Essentially a competition between the protein and the ion for water molecules for hydration. ... (20 Mar 1998) ...

lypressin
<chemical> 8-lysyl vasopressin. The porcine antidiuretic hormone most frequently used clinically. A cyclic nonapeptide with lysine in position 8 of the chain; it is used to treat diabetes insipidus and as haemostatic because of its vasoconstrictor action. ... Pharmacological action: haemostatics, renal agents, vasoconstrictor agents. ... Chemic …

lyra
1. <astronomy> A northern constellation, the Harp, containing a white star of the first magnitude, called Alpha Lyrae, or Vega. ... 2. <anatomy> The middle portion of the ventral surface of the fornix of the brain; so called from the arrangement of the lines with which it is marked in the human brain. ... Origin: L. Lyra, Gr. See Lyre. …

lyra uterina
Synonym for palmate folds ... The two longitudinal ridges, anterior and posterior, in the mucous membrane lining the cervix uteri, from which numerous secondary folds, or rugae, branch off. ... Synonym: plicae palmatae, arbor vitae uteri, lyra uterina. ... (05 Mar 2000) ...

lyrate
<zoology> Deeply lobed, with a large terminal lobe and smaller lateral ones. ... (20 Mar 1998) ...

lyre
1. A stringed instrument of music; a kind of harp much used by the ancients, as an accompaniment to poetry. ... The lyre was the peculiar instrument of Apollo, the tutelary god of music and poetry. It gave name to the species of verse called lyric, to which it originally furnished an accompaniment ... 2. <astronomy> One of the constellations; L …

lyre bird
<ornithology> Any one of two or three species of Australian birds of the genus Menura. The male is remarkable for having the sixteen tail feathers very long and, when spread, arranged in the form of a lyre. The common lyre bird (Menura superba), inhabiting new South Wales, is about the size of a grouse. Its general colour is brown, with rufou …

Lys
Symbol for lysine, or its radicals in peptides. ... (05 Mar 2000) ...

lysaemia
<haematology> Disintegration or dissolution of red blood cells and the occurrence of haemoglobin in the circulating plasma and in the urine. ... Origin: Lyso-+ G. Haima, blood ... (05 Mar 2000) ...

lysate
<biochemistry> Material produced by the destructive process of lysis. ... (05 Mar 2000) ...

lyse
<biochemistry> To break up, to disintegrate, to effect lysis. ... Synonym: lyze. ... (05 Mar 2000) ...

lysergamide
Synonym for lysergic acid amide ... A psychotomimetic agent present in Rivea corymbosa and Ipomoea tricolor; possesses less hallucinogenic potency than does lysergic acid diethylamide. ... Synonym: ergine, lysergamide. ... (05 Mar 2000) ...

lysergic acid
<chemical> Chemical name: Ergoline-8-carboxylic acid, 9,10-didehydro-6-methyl-, (8beta)- ... (12 Dec 1998) ...

lysergic acid amide
A psychotomimetic agent present in Rivea corymbosa and Ipomoea tricolor; possesses less hallucinogenic potency than does lysergic acid diethylamide. ... Synonym: ergine, lysergamide. ... (05 Mar 2000) ...

lysergic acid diethylamide
<chemical> A centrally acting agent with hallucinogenic properties, may precipitate psychosis. ... Acronym: LSD ... (27 Sep 1997) ...

lysergic acid monoethylamide
A psychotomimetic agent present in Rivea corymbosa and Ipomoea tricolor; possesses less hallucinatory potency than does lysergic acid diethylamide. ... (05 Mar 2000) ...

lysergide
Synonym for lysergic acid diethylamide ... <chemical> A centrally acting agent with hallucinogenic properties, may precipitate psychosis. ... Acronym: LSD ... (27 Sep 1997) ...

lysergol
A semisynthetic ergot alkaloid. ... (05 Mar 2000) ...

lysergyl peptide synthetase
<enzyme> Multifunctional enzyme which forms non-cyclol d-lysergyl peptide lactams; consists of two polypeptide chains - lps 1 binds the 3 amino acids (ala, phe and pro) of the peptide nucleus and lps 2 binds d-lysergic acid ... Registry number: EC 6.3.2.- ... Synonym: d-lysergylpeptide synthetase ... (26 Jun 1999) ...

lysin
<protein> An antibody that induces lysis. ... (09 Oct 1997) ...

lysinaemia
See: hyperlysinaemia. ... (05 Mar 2000) ...

lysine
<amino acid> The only carrier of a side chain primary amino group in proteins. Has important structural and chemical roles in proteins. ... (18 Nov 1997) ...

lysine carboxypeptidase
<enzyme> A serine carboxypeptidase that removes c-terminal amino acids, preferentially lysine, from peptides and proteins. It inactivates bradykinin by this action. ... Registry number: EC 3.4.17.3 ... (12 Dec 1998) ...

lysine decarboxylase
<enzyme> Do not confuse with cada atpase ... Registry number: EC 4.1.1.18 ... Synonym: cad a gene product, cada lysine decarboxylase ... (26 Jun 1999) ...

lysine epsilon-dehydrogenase
<enzyme> From agrobacterium tumefaciens; forms alpha-aminoadipate delta-semialdehyde which is spontaneously converted to delta 1-piperideine-6-carboxylate ... Registry number: EC 1.4.1.- ... Synonym: l-lysine epsilon-dehydrogenase ... (26 Jun 1999) ...

lysine monooxygenase
<enzyme> Minor descriptor (75-82); online and index medicus search oxygenases (75-82) ... Registry number: EC 1.13.12.2 ... Synonym: lysine oxygenase ... (26 Jun 1999) ...

lysine N-epsilon hydroxylase
<enzyme> Do not confuse with lysine hydroxylase, which forms 5-hydroxylysine ... Registry number: EC 1.14.13.- ... Synonym: n-epsilon lysine monooxygenase, iucd protein, aera protein, lysine n(6)-hydroxylase ... (26 Jun 1999) ...

lysine racemase
<enzyme> Interconverts the d- and l-isomers ... Registry number: EC 5.1.1.5 ... (26 Jun 1999) ...

lysine-C peptidase
<enzyme> Used in amino acid sequence determinations ... Registry number: EC 3.4.99.- ... Synonym: lysine specific peptidase ... (26 Jun 1999) ...

lysine-p-nitroanilide hydrolase
<enzyme> Hydrolyses a wide variety of di-, tri-, and tetrapeptides, and polypeptides up to 15 amino acids; it is blocked only if proline is in the penultimate position from n-terminus or if n-terminus is blocked, e.g. Pyroglutamyl residue ... Registry number: EC 3.4.- ... Synonym: lysine-4-nitroanilide hydrolase, lys-pna hydrolase ... (26 Jun 19 …

lysine-tRNA ligase
<enzyme> An enzyme that activates lysine with its specific transfer RNA. ... Chemical name: L-Lysine:tRNA(Lys) ligase (AMP-forming) ... Registry number: EC 6.1.1.6 ... (12 Dec 1998) ...

lysinium
The cation form of lysine, either lysinium (+1) or lysinium (+2). ... (05 Mar 2000) ...

lysinoalanine
<chemical> N(6)-(2-amino-2-carboxyethyl)-l-lysine. An unusual amino acid, not a dipeptide, which has been found in proteins of cooked foods. It is formed in food that is heated or treated with alkali. Has been implicated in nephrocytomegalia in rats. ... Chemical name: L-Lysine, N6-(2-amino-2-carboxyethyl)- ... (12 Dec 1998) ...

lysinogen
An antigen that stimulates the formation of a specific lysin. ... (05 Mar 2000) ...

lysinogenic
Having the property of a lysinogen. ... (05 Mar 2000) ...

lysinuria
The presence of lysine in the urine. ... (05 Mar 2000) ...

lysinuric protein intolerance
An autosomal recessive disorder characterised by elevated levels of dibasic amino acids (e.g., l-lysine, l-arginine, and l-ornithine) in the urine; apparently due to a defect in dibasic amino acid transport. ... (05 Mar 2000) ...

lysis
<cell biology> Rupture of cell membranes and loss of cytoplasm. ... (18 Nov 1997) ...