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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

Korsakoff's syndrome
<syndrome> May occur as a sequel to chronic alcohol abuse. Features include personality changes, confabulation, psychosis, disorientation, polyneuritis, insomnia and hallucinations. ... (27 Sep 1997) ...

Koshland-Nemethy-Filmer model
<biochemistry, chemistry> A model to explain the allosteric form of cooperativity; in this model, in the absence of ligands, the protein exists in only one conformation; upon binding, the ligand induces a conformational change that may be transmitted to other subunits. ... Synonym: Adair-Koshland-Nemethy-Filmer model, induced fit model. ... (05 …

Koshland, Daniel
<person> U.S. Biochemist, *1920. ... See: Adair-Koshland-Nemethy-Filmer model, Koshland-Nemethy-Filmer model. ... (05 Mar 2000) ...

Kossa stain
Synonym for von Kossa stain ... <technique> A stain for calcium in mineralised tissue, utilizing a silver nitrate solution followed by sodium thiosulfate; calcified bone but not osteoid is stained brown to black. ... Synonym: Kossa stain. ... (05 Mar 2000) ...

Kostmann syndrome
<syndrome> Severe infantile agranulocytosis, an inherited disorder of infancy characterised by severe, recurrent infections, and neutropenia. ... (05 Mar 2000) ...

koulan
<zoology> A wild horse (Equus, or Asinus, onager) inhabiting the plants of Central Asia. ... Synonym: gour, khur, and onager. ... Alternative forms: kulan. ... It is sometimes confounded with the dziggetai, to which it is closely related. It is gray in winter, but fulvous in summer. It has a well defined, dark, dorsal stripe, and a short, erect …

Koyanagi, Yosizo
<person> Japanese ophthalmologist, 1880-1954. ... See: Vogt-Koyanagi syndrome. ... (05 Mar 2000) ...

Kr
Symbol for krypton. ... (05 Mar 2000) ...

kra-kra
Synonym for craw-craw ... A term applied in west Africa to a pruritic papular skin eruption, which may lead to ulceration; some cases are caused by Onchocerca. ... Synonym: kra-kra. ... (05 Mar 2000) ...

Krabbe, Knud
<person> Danish neurologist, 1885-1961. ... See: Krabbe's disease, Christensen-Krabbe disease. ... (05 Mar 2000) ...

Krabbe's disease
Synonym for globoid cell leukodystrophy ... <radiology> Dysmyelinating disease, autosomal recessive, usually presents by 1 yr, specific enzyme deficiency identified, rapid spontaneous nystagmus, poikilothermia ... Synonym: Krabbe leukodystrophy ... (12 Dec 1998) ...

kraken
A fabulous Scandinavian sea monster, often represented as resembling an island, but sometimes as resembling an immense octopus. 'To believe all that has been said of the sea serpent or kraken, would be credulity; to reject the possibility of their existence, would be presumption.' (Goldsmith) 'Like a kraken huge and black.' (Longfellow) ... Origin: …

Krantz, Kermit
<person> U.S. Obstetrician-gynecologist, *1923. ... See: Marshall-Marchetti-Krantz operation. ... (05 Mar 2000) ...

Kraske, Paul
<person> German surgeon, 1851-1930. ... See: Kraske's operation. ... (05 Mar 2000) ...

Kraske's operation
Removal of the coccyx and excision of the left wing of the sacrum in order to afford approach for resection of the rectum for cancer or stenosis. ... (05 Mar 2000) ...

kraurosis vulvae
An atrophic disease affecting the female external genitalia, most often of older women, resulting in drying and shriveling of the parts, and marked by leukoplakic patches on the mucosa, itching, dyspareunia, dysuria, and soreness. It occurs most commonly as a result of lichen sclerosus et atrophicus of the vulva, but may be associated with other ty …

Krause graft
A full-thickness skin graft. ... Synonym: Krause-Wolfe graft. ... (05 Mar 2000) ...

Krause-Wolfe graft
Synonym for Krause graft ... A full-thickness skin graft. ... Synonym: Krause-Wolfe graft. ... (05 Mar 2000) ...

Krause, Fedor
<person> German surgeon, 1857-1937. ... See: Krause graft, Krause's method, Wolfe-Krause graft. ... (05 Mar 2000) ...

Krause, Karl
<person> German anatomist, 1797-1868. ... See: Krause's glands, Krause's ligament, Krause's muscle. ... (05 Mar 2000) ...

Krause, Wilhelm
<person> German anatomist, 1833-1910. ... See: Krause's bone, Krause's end bulbs, Krause's respiratory bundle, Krause's valve. ... (05 Mar 2000) ...

Krause's bone
Small bone (secondary ossification centre) in the triradiate cartilage between the ilium, the ischium, and the pubic bone in the growing acetabulum. ... (05 Mar 2000) ...

Krause's end bulbs
Nerve terminals in skin, mouth, conjunctiva, and other parts, consisting of a laminated capsule of connective tissue enclosing the terminal, branched, convoluted ending of an afferent nerve fibre; generally believed to be sensitive to cold. ... Synonym: corpuscula bulboidea, bulboid corpuscles. ... (05 Mar 2000) ...

Krause's glands
See: accessory lacrimal glands. ... Gland's in the mucous membrane of the tympanic cavity. ... See: accessory lacrimal glands. ... (05 Mar 2000) ...

Krause's ligament
Synonym for transverse perineal ligament ... <anatomy> The thickened anterior border of the urogenital diaphragm, formed by the fusion of its two fascial layers. ... Synonym: ligamentum transversum perinei, Krause's ligament, ligamentum transversum pelvis, transverse ligament of pelvis, transverse ligament of perineum. ... (05 Mar 2000) ...

Krause's method
Synonym for Krause graft ... A full-thickness skin graft. ... Synonym: Krause-Wolfe graft. ... (05 Mar 2000) ...

Krause's muscle
Synonym for cutaneomucous muscle ... <anatomy> The 'sucking muscle,' a labial muscle formed by sagittal fibres running from the skin to the mucous membrane. ... Synonym: Aeby's muscle, Bovero's muscle, compressor muscle of lips, Klein's muscle, Krause's muscle, mucocutaneous muscle, musculus cutaneomucosus. ... (05 Mar 2000) ...

Krause's respiratory bundle
Synonym for solitary tract ... A slender, compact fibre bundle extending longitudinally through the dorsolateral region of the medullary tegmentum, surrounded by the nucleus of the solitary tract, below the obex decussating over the central canal, and descending over some distance into the upper cervical segments of the spinal cord. It is composed o …

Krause's valve
Synonym for Beraud's valve ... A small fold in the interior of the lacrimal sac at its junction with the lacrimal duct. ... Synonym: Krause's valve. ... (05 Mar 2000) ...

kreatin
Synonym for creatine ... <biochemistry> A compound which is made by the body and is used to store energy in the form of phosphate molecules. ... When phosphate molecules are attached to it, it is called creatine phosphate and is capable of donating phosphate to ADP in order to make ATP. (ATP is the molecule which is converted into ADP with a re …

kreatinin
Synonym for creatinine ... <biochemistry, nephrology> A waste product of protein metabolism that is found in the urine. ... Can be measured to assess overall kidney function. An abnormally elevated blood creatinine level is seen in those individuals with kidney insufficiency and kidney failure. ... (27 Sep 1997) ...

krebiozen
An extract from peach kernels, the composition of which has not been fully described but which gained notoriety in the 1960's and 1970's as a dubious but exploited remedy for cancer; currently not regarded as effective. ... Origin: Ger. Krebs, crab, cancer ... (05 Mar 2000) ...

Krebs cycle
<biochemistry> Tricarboxylic acid cycle or citric acid cycle. ... (18 Nov 1997) ...

Krebs-Henseleit cycle
Synonym for urea cycle ... The metabolic pathway isfound in vertebrates and takes place in theliver, in it, urea is synthesised from amino acids and carbon dioxide. ... (09 Oct 1997) ...

Krebs-Kornberg cycle
Synonym for glyoxylic acid cycle ... A catabolic cycle in plants and microorganisms like that of the tricarboxylic acid cycle in animals; its key reaction is the condensation of acetyl-CoA with glyoxylic acid to malic acid (analogous to the condensation of acetyl-CoA and oxaloacetic acid to form citric acid in the tricarboxylic acid cycle). ... Synon …

Krebs-Ringer solution
A modification of Ringer's solution, prepared by mixing NaCl, KCl, CaCl2, MgSO4, and phosphate buffer, pH 7.4. ... (05 Mar 2000) ...

Krebs, Hans Adolph
<person> A German-born British chemist who was awarded the Nobel Prize for his research in intermediate metabolism. ... Lived: 1900-1981. ... (13 Nov 1997) ...

Krebs, Sir Hans Adolph
<person> German biochemist in England and Nobel laureate, 1900-1981. ... See: Krebs cycle, Krebs-Henseleit cycle, Krebs-Ringer solution. ... (05 Mar 2000) ...

kreotoxin
<protein> Term for any basic (pH over 7) toxin produced by bacteria or fungi in meat. ... (09 Oct 1997) ...

Kretschmann, Friederich
<person> German otologist, 1858-1934. ... See: Kretschmann's space. ... (05 Mar 2000) ...

Kretschmann's space
A slight depression in the epitympanic recess below the superior recess of tympanic membrane. ... (05 Mar 2000) ...

Kreysig, Friedrich
<person> German physician, 1770-1839. ... See: Kreysig's sign, Heim-Kreysig sign. ... (05 Mar 2000) ...

Kreysig's sign
Synonym for Heim-Kreysig sign ... <clinical sign> In adherent pericardium, an indrawing of the intercostal spaces, synchronous with the cardiac systole. ... Synonym: Kreysig's sign. ... (05 Mar 2000) ...

kringle
<molecular biology> Triple looped, disulphide linked protein domains, found in some serine proteases and other plasma proteins, including plasminogen (5 copies), tissue plasminogen activator (2 copies), thrombin (2 copies), hepatocyte growth factor (4 copies), apolipoprotein A (38 copies). ... (18 Nov 1997) ...

kringles
Triple-looped protein domains linked by disulfide bonds. These common structural motifs, so-named for their resemblance to danish pastries known as kringlers, play a role in binding membranes, proteins, and phospholipids as well as in regulating proteolysis. Kringles are also present in coagulation-related and fibrinolytic proteins and other plasma …

Krogh
August, Danish physiologist and Nobel laureate, 1874-1949. ... See: Krogh spirometer. ... (05 Mar 2000) ...

Krogh spirometer
A water-sealed spirometer in which the bell is a large, shallow, rectangular box rotating slightly around a horizontal axis extending along one edge, with an arm extending beyond that axis to a counterbalancing weight; comparable to a wedge spirometer. ... (05 Mar 2000) ...

Kromayer
Ernst L.F., German dermatologist, 1862-1933. ... See: Kromayer's lamp. ... (05 Mar 2000) ...

Kromayer's lamp
A U-shaped quartz lamp of mercury vapor, giving out actinic rays; used in the treatment of skin diseases. ... (05 Mar 2000) ...

Kronecker
Karl H., Swiss physiologist, 1839-1914. ... See: Kronecker's stain. ... (05 Mar 2000) ...

Kronecker's stain
<technique> A 5% sodium chloride stain rendered faintly alkaline with sodium carbonate, used in the examination of fresh tissues under the microscope. ... (05 Mar 2000) ...

Kronig
Georg, German physician, 1856-1911. ... See: Kronig's isthmus, Kronig's steps. ... (05 Mar 2000) ...

Kronig's isthmus
The narrow straplike portion of the resonant field that extends over the shoulder, connecting the larger areas of resonance over the pulmonary apex in front and behind. ... (05 Mar 2000) ...

Kronig's steps
Extension of the lower part of the right border of absolute cardiac dullness in hypertrophy of the right heart. ... (05 Mar 2000) ...

Kronlein
Rudolf U., Swiss surgeon, 1847-1910. ... See: Kronlein operation, Kronlein's hernia. ... (05 Mar 2000) ...

Kronlein operation
Orbital decompression through the anterior lateral wall of the orbit. ... (05 Mar 2000) ...

Kronlein's hernia
Synonym for properitoneal inguinal hernia ... A complicated hernia having a double sac, one part in the inguinal canal, the other projecting from the internal inguinal ring in the subperitoneal tissues. ... Synonym: hernia en bissac, Kronlein's hernia. ... (05 Mar 2000) ...

krooman
<ethnology> One of a negro tribe of Liberia and the adjacent coast, whose members are much employed on shipboard. ... (21 Mar 1998) ...

krp dibasic endopeptidase
<enzyme> A type I membrane-bound endopeptidase that cleaves after pairs of dibasic residues; isolated from schizosaccharomyces pombe; genbank x82435; do not confuse with krp protein ... Registry number: EC 3.4.21.- ... Synonym: kex2-related protease, dibasic endopeptidase krp, krp1 endopeptidase ... (26 Jun 1999) ...

Krueger instrument stop
A mechanical device limiting the insertion of a root canal instrument into a canal. ... (05 Mar 2000) ...

krukenberg tumour
<radiology> Ovarian metastasis of stomach carcinoma, also: colon, breast, other mucin-gland organs, 6% of malignant ovarian tumours ... (12 Dec 1998) ...

Krukenberg, Adolph
<person> German anatomist, 1816-1877. ... See: Krukenberg's veins. ... (05 Mar 2000) ...

Krukenberg, Friedrich
<person> German pathologist, 1871-1946. ... See: Krukenberg's amputation, Krukenberg's spindle, Krukenberg's tumour. ... (05 Mar 2000) ...

Krukenberg's amputation
A cineplastic amputation at the carpus with the distal end of the forearm used to create a fork-like stump; especially valuable in the blind because the stump has proprioception. ... (05 Mar 2000) ...

Krukenberg's spindle
A vertical fusiform area of melanin pigmentation on the posterior surface of the central cornea. ... (05 Mar 2000) ...

Krukenberg's tumour
A metastatic carcinoma of the ovary, usually bilateral and secondary to a mucous carcinoma of the stomach, which contains signet-ring cells filled with mucus. ... (05 Mar 2000) ...

Krukenberg's veins
Synonym for central veins of liver ... The terminal branches of the hepatic veins that lie centrally in the hepatic lobules and receive blood from the liver sinusoids. ... Synonym: venae centrales hepatis, Krukenberg's veins. ... (05 Mar 2000) ...

Kruse, Walther
<person> German bacteriologist, 1864-1943. ... See: Kruse's brush, Shiga-Kruse bacillus. ... (05 Mar 2000) ...

Kruse's brush
A bunch of fine platinum wires attached to a holder; used in bacteriological work to spread material over the surface of a culture medium. ... (05 Mar 2000) ...

krymo-
Kryo- ... See: crymo-, cryo-. ... (05 Mar 2000) ...

krypton
<chemical> A noble gas that is found in the atmosphere. It has the atomic symbol kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs. ... Chemical name: Krypton ... (12 Dec 1998) ...

krypton radioisotopes
Unstable isotopes of krypton that decay or disintegrate emitting radiation. Kr atoms with atomic weights 74-77, 79, 81, 85, and 87-94 are radioactive krypton isotopes. ... (12 Dec 1998) ...

ksgA methyltransferase
<enzyme> Forms n6-dimethyladenosine at residues a1518 and a1519 in e. Coli 16s ribosomal RNA ... Registry number: EC 2.1.1.- ... Synonym: 16s rrna dimethylase ... (26 Jun 1999) ...

KSR-1 protein kinase
<enzyme> Ksr - kinase suppressor of ras; a raf-related kinase involved in ras-mediated signal transduction; genbank u38820 ... Registry number: EC 2.7.1.- ... Synonym: ksr-1 gene product ... (26 Jun 1999) ...

Ku antibodies
Ku antibodies (a DNA-binding protein) are found in approximately 15-50% of patients with systemic lupus erythematosus, mixed connective tissue disease, Sjögren syndrome and scleroderma, in about 5- 15% of patients with myositis in the United States and possibly in a larger proportion in Japan and in about 23% (7/31) of patients with primary pulmona …

KUB
Kidney, ureter, and bladder. ... (12 Dec 1998) ...

kub film
An X-ray showing the kidney, ureter, and bladder. This is in reality a plain abdominal x-ray and includes other structures such as the diaphragm above and the pelvis below. ... (12 Dec 1998) ...

kubisagari
Synonym: vestibular neuronitis. ... Origin: Jap. Kubi, head, neck, + sagaru, to hang down ... (05 Mar 2000) ...

kuda
<zoology> The East Indian tapir. ... (21 Mar 1998) ...

Kufs
H., German psychiatrist, 1871-1955. ... See: Kufs disease. ... (05 Mar 2000) ...

Kufs disease
cerebral sphingolipidosis, adult type ...

Kugel's anastomotic artery
<anatomy, artery> A vessel of variable origin, most commonly a branch of the circumflex artery, coursing posteriorly through the base of the interatrial septum toward the crux of the heart, anastomosing with coronary artery branches supplying the atrioventricular node, the atrioventricular bundle (bundle of His), and the upper posterior walls …

Kugelberg
Eric, Swedish neurologist, 1913-1983. ... See: Kugelberg-Welander disease, Wohlfart-Kugelberg-Welander disease. ... (05 Mar 2000) ...

Kugelberg-Welander disease
Synonym for juvenile spinal muscular atrophy ... Slowly progressive proximal muscular weakness and wasting, beginning in childhood, caused by degeneration of motor neurons in the anterior horns of the spinal cord; onset usually between 2 and 17 years of age; usually autosomal recessive inheritance. ... Synonym: juvenile muscular atrophy, Kugelberg-We …

Kuhne
Wilhelm (Willy) F., German physiologist and histologist, 1837-1900. ... See: Kuhne's fibre, Kuhne's methylene blue, Kuhne's phenomenon, Kuhne's plate, Kuhne's spindle. ... (05 Mar 2000) ...

Kuhne's fibre
Artificial muscle fibre made by filling the intestine of an insect with a growth of myxomycetes; used to demonstrate the contractility of protoplasm. ... (05 Mar 2000) ...

Kuhne's methylene blue
Methylene blue in absolute alcohol and phenol solution. ... (05 Mar 2000) ...

Kuhne's phenomenon
When a constant current is passed through a muscle, an undulation is seen to pass from the positive to the negative pole. ... (05 Mar 2000) ...

Kuhne's plate
The endplate of a motor nerve fibre in a muscle spindle. ... (05 Mar 2000) ...

Kuhne's spindle
Synonym for neuromuscular spindle ... A fusiform end organ in skeletal muscle in which afferent and a few efferent nerve fibres terminate; it contains from 3 to 10 striated muscle fibres (intrafusal fibres) that are much smaller than the ordinary muscle fibres, are separated from them by a capsule that encloses the organ, and are innervated by the t …

Kuhnt
Hermann, German ophthalmologist, 1850-1925. ... See: Kuhnt's spaces, Kuhnt-Junius degeneration, Kuhnt-Junius disease. ... (05 Mar 2000) ...

Kuhnt-Junius degeneration
An obsolete eponym for disciform degeneration. ... Synonym: Kuhnt-Junius disease. ... (05 Mar 2000) ...

Kuhnt-Junius disease
Synonym for Kuhnt-Junius degeneration ... An obsolete eponym for disciform degeneration. ... Synonym: Kuhnt-Junius disease. ... (05 Mar 2000) ...

Kuhnt's spaces
Shallow diverticula or recesses between the ciliary body and ciliary zonule which open into the posterior chamber of the eye. ... (05 Mar 2000) ...

kukang
<zoology> The slow lemur. ... (21 Mar 1998) ...

Kulchitsky
Nicholas, Russian histologist, 1856-1925. ... See: Kulchitsky cells. ... (05 Mar 2000) ...

Kulchitsky cells
Synonym for enteroendocrine cells ... Cell's with granules that may be either argentaffinic or argyrophilic; the cell's, scattered throughout the digestive tract, are of several varieties and are believed to produce at least 20 different gastrointestinal hormones and neurotransmitters. ... Synonym: enterochromaffin cells, Kulchitsky cells. ... (05 Mar …

Kulchitsky, Nicholas
<person> B. Kronstadt, 1856. Was an Anatomist and a Histologist. Taught first in his own University of Kharkov and in 1893 became Professor of Histology. Later was appointed Director of Education in Kasan and in 1915 went ot St. Petersburg. After the revolution came to England and worked at University College, London. D. Jan. 30th, 1925, as t …

Kulz
Rudolph E., German physician, 1845-1895. ... See: Kulz's cylinder. ... (05 Mar 2000) ...

Kulz's cylinder
Synonym for coma cast ... A renal cast of strongly refracting granules said to be indicative of imminent coma in diabetes. ... Synonym: Kulz's cylinder. ... (05 Mar 2000) ...