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 mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


hsp
heat shock protein ...

hsp70
<molecular biology> Widely distributed group of conserved heat-shock proteins of average weight 70 kD. Possess ATP binding domains and may be involved in protein folding or export. ... (18 Nov 1997) ...

hsp90
<molecular biology> Widely distributed group of conserved heat-shock proteins of average weight 90 kD. Exact function unknown, but are found associated with steroid hormone receptors and tyrosine kinase oncogene products. May also bind actin and tubulin. ... (18 Nov 1997) ...

hst
<oncogene> Human oncogene that encodes a member of the FGF family. ... (18 Nov 1997) ...

HSV
Synonym for herpes simplex virus ... <virology> A virus in the family Herpesviridae. Type 1 HSVcauses blisters on the lips, nostrils, and possibly on the lining of the eyelids. Type 2 HSV causes blisters and lesions on and aroundgenitalia. ... (09 Oct 1997) ...

HSV-1 ICP35 protease
<enzyme> Has been sequenced; responsible for proteolytic processing of infected cell protein 35 (icp35); protease cleavage produces two polypeptides, prn and icp35a; do not confuse with hsv-1 assembly protein icp35 ... Registry number: EC 3.4.21.- ... Synonym: herpes simplex virus-1 icp35 proteinase, icp35 protease, hsv-1, ul26 protein, hsv-1, …

ht
Abbreviation for height (and also heart). ... (12 Dec 1998) ...

ht29 cell
<cell culture> Human colonic adenocarcinoma cells that are able to express differentiation features characteristic of mature intestinal cells. These cells have mainly been used for studies related to glucose metabolism and hormone receptors. ... (12 Dec 1998) ...

HTLV
Synonym for human t-lymphotropic virus ... <virology> Type i: A human, single-stranded RNA retrovirus from the subfamily Oncovirinae which causes adult T-cell leukaemia and T-cell lymphoma and may also be involved in certain demyelinating diseases (diseases where the protective myelin sheath around nerve fibres are destroyed). HTLV-I is closel …

HTLV-1 protease
<enzyme> Has been sequenced ... Registry number: EC 3.4.23.- ... Synonym: human t-cell leukaemia virus type 1 protease, pr14, HTLV-1 proteinase ... (26 Jun 1999) ...

HTLV-blv antibodies
Antibodies reactive with various types of human T-cell leukaemia/lymphoma antigens or bovine leukaemia virus antigens. ... (12 Dec 1998) ...

HTLV-blv antigens
Antigens associated with the HTLV-blv viruses. Htlv-I antigens and HTLV-II antigens belong to this group. ... (12 Dec 1998) ...

HTLV-blv infections
Infections caused by the HTLV or blv retroviruses. They include human T-cell leukaemia-lymphoma and adult T-cell leukaemia. ... (12 Dec 1998) ...

HTLV-blv viruses
Genus of the family retroviridae consisting of exogenous horizontally-transmitted viruses found in a few groups of mammals. Infections caused by these viruses include human b or adult T-cell leukaemia/lymphoma, and bovine leukaemia. ... (12 Dec 1998) ...

HTLV-I
<virology> A species of HTLV-blv viruses isolated from mature t4 cells in patients with t-lymphoproliferation malignancies. It causes adult T-cell leukaemia (atl), T-cell lymphoma, and is involved in mycosis fungoides, sezary syndrome and tropical spastic paraparesis. ... (12 Dec 1998) ...

HTLV-I antibodies
Antibodies reactive with the HTLV-I antigens. ... (12 Dec 1998) ...

HTLV-I antigens
Antigens associated with the HTLV-I virus. ... (12 Dec 1998) ...

HTLV-II
<virology> A species of HTLV-blv viruses that can transform normal T-lymphocytes and can replicate in both t- and B-cell lines. The virus is related to but distinct from HTLV-I. It is associated with T-cell hairy cell leukaemia, a relatively benign disease. ... (12 Dec 1998) ...

HTLV-II antibodies
Antibodies reactive with the HTLV-II antigens. ... (12 Dec 1998) ...

HTLV-II antigens
Antigens associated with the HTLV-II virus. ... (12 Dec 1998) ...

HTLV-III
<abbreviation> Human T-cell lymphotropic virus type III. ... See: human immunodeficiency virus. ... (05 Mar 2000) ...

hU
<abbreviation> Dihydrouridine. ... (05 Mar 2000) ...

Hu antigens
he antigens ...

Hubbard tank
<apparatus> A large tank, usually filled with warm water, used for therapeutic exercises in a program of physiotherapy. ... (05 Mar 2000) ...

Hubrecht, Ambrosius
<person> Dutch zoologist and comparative anatomist, 1853-1915. ... See: Hubrecht's protochordal knot. ... (05 Mar 2000) ...

Hubrecht's protochordal knot
Synonym for primitive node ... A local thickening of the blastoderm at the cephalic end of the primitive streak of the embryo. ... Synonym: Hensen's knot, Hensen's node, Hubrecht's protochordal knot, primitive knot, protochordal knot. ... (05 Mar 2000) ...

Huckel's rule
<chemistry> The number of depolarised electrons in an aromatic ring is equal to 4n + 2 where n is zero or any positive integer; l-tyrosine, l-phenylalanine, l-tryptophan, and l-histidine (when the imidazole ring is deprotonated) obey this rule. ... (05 Mar 2000) ...

Hucker-Conn stain
<technique> A crystal violet-ammonium oxalate mixture used in Gram's stain. ... (05 Mar 2000) ...

huckleberry
<botany> The edible black or dark blue fruit of several species of the American genus Gaylussacia, shrubs nearly related to the blueberries (Vaccinium), and formerly confused with them. The commonest huckelberry comes from G. Resinosa. ... The shrub that bears the berries. ... Synonym: whortleberry. Squaw huckleberry. See Deeberry. ... Origin: C …

Hudson-Stahli line
<clinical sign, ophthalmology> A brown, horizontal line across the lower third of the cornea, occasionally seen in the aged and also in association with corneal opacities. ... (05 Mar 2000) ...

Hudson, Arthur Cyril
<person> British ophthalmologist, 1875-1962. ... See: Hudson-Stahli line. ... (05 Mar 2000) ...

Hueck, Alexander
<person> German anatomist, 1802-1842. ... See: Hueck's ligament. ... (05 Mar 2000) ...

Hueck's ligament
Synonym for trabecular reticulum ... The network of fibres (pectinate ligaments) at the iridocorneal angle between the anterior chamber of the eye and the venous sinus of the sclera; it contains spaces between the fibres that are involved in drainage of the aqueous humor, and is composed of two portions: the corneoscleral part, the part attached to …

Huet, G
<person> Dutch physician, *1879. ... See: Pelger-Huet nuclear anomaly. ... (05 Mar 2000) ...

Hueter, Karl
<person> German surgeon, 1838-1882. ... See: Hueter's manoeuvre, Hueter's sign. ... (05 Mar 2000) ...

Hueter's manoeuvre
<technique> Pressing the patient's tongue downward and forward with the left forefinger in passing a stomach tube. ... (05 Mar 2000) ...

Hueter's sign
<clinical sign> In a case of fracture, the vibration expected on tapping the bone is not transmitted when tissue intervenes between the fractured parts of bone. ... (05 Mar 2000) ...

Hufner, Carl Gustav von
<person> German physician, 1840-1908. ... See: Hufner's equation. ... (05 Mar 2000) ...

Hufner's equation
<physiology> An equation expressing the relationship between myoglobin dissociation and oxygen partial pressure: ([MBO2]/[Mb]) = (K x pO2). ... (05 Mar 2000) ...

Huggins, Charles
<person> Canadian-U.S. Surgeon and Nobel laureate, 1901-1994. ... See: Huggins' operation. ... (05 Mar 2000) ...

Huggins' operation
<procedure> Orchidectomy performed for palliation or cure of cancer of the prostate. ... Synonym: castration. ... (05 Mar 2000) ...

Hughes-Stovin syndrome
<syndrome> A syndrome characterised by aneurysms of the large and small pulmonary artery and thrombosis of peripheral veins and dural sinuses. ... (05 Mar 2000) ...

HUGO
Human Genome Organisation (the international organisation concerned with human genome research). ... (12 Dec 1998) ...

Huguier, Pierre
<person> French surgeon, 1804-1873. ... See: Huguier's canal, Huguier's circle, Huguier's sinus. ... (05 Mar 2000) ...

Huguier's canal
Synonym for anterior canaliculus of chorda tympani ... <anatomy> A canal in the petrotympanic or glaserian fissure, near its posterior edge, through which the chorda tympani nerve issues from the skull. ... Synonym: Civinini's canal, Huguier's canal, iter chordae anterius. ... (05 Mar 2000) ...

Huguier's circle
<anatomy> Anastomosis around the isthmus of the uterus (junction of the cervix with the body) between the right and left uterine arteries. ... (05 Mar 2000) ...

Huguier's sinus
Synonym for fossula fenestrae vestibuli ... A depression on the medial wall of the middle ear which has the fenestra vestibulae (oval window) in its lower portion. ... Synonym: Huguier's sinus, little fossa of the vestibular window, little fossa of the vestibular round window. ... (05 Mar 2000) ...

Huhner test
<investigation> Determination of sperm quantity and motility in specimens obtained from the cervical canal following coitus, performed around the time of ovulation. ... (05 Mar 2000) ...

Huhner, Max
<person> U.S. Urologist, 1873-1947. ... See: Huhner test. ... (05 Mar 2000) ...

hull
1. The outer covering of anything, particularly of a nut or of grain; the outer skin of a kernel; the husk. ... 2. The frame or body of a vessel, exclusive of her masts, yards, sails, and rigging. Hull down, said of a ship so distant that her hull is concealed by the convexity of the sea. ... Origin: OE. Hul, hol, shell, husk, AS. Hulu; akin to G. Hu …

Hull's triad
<clinical sign> The association of diastolic gallop, anasarca, and small pulse pressure. ... (05 Mar 2000) ...

hum
<cardiology, clinical sign> A low continuous murmur. ... Origin: echoic ... (05 Mar 2000) ...

human
Belonging to man or mankind; having the qualities or attributes of a man; of or pertaining to man or to the race of man; as, a human voice; human shape; human nature; human sacrifices. 'To err is human; to forgive, divine.' (Pope) ... Origin: L. Humanus; akin to homo man: cf. F. Humain. See Homage, and cf. Humane, Omber. ... Source: Websters Dictiona …

human a1-proteinase inhibitor
Synonym for a1-antitrypsin ... A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of al …

human activities
Activities performed by humans. ... (12 Dec 1998) ...

human antihemophilic factor
A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia. ... Synonym: antihemophilic globulin, human antihemophilic fraction. ... (05 Mar 2000) ...

human antihemophilic fraction
Synonym for human antihemophilic factor ... A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia. ... Synonym: antihemophilic globulin, human antihemophilic fraction. ... (05 Mar 2000) ...

human babesiosis
A rare human disease caused by infection with Babesia species (most frequently B. Divergens in Europe and B. Microti in the U.S.) that has been fatal in some splenectomised individuals. ... (05 Mar 2000) ...

human body
The human being as a non-anatomical and non-zoological entity. The emphasis is on the philosophical or artistic treatment of the human being, and includes lay and social attitudes toward the body in history. ... (12 Dec 1998) ...

human botfly
Synonym for Dermatobia hominis ... A large, blue, brown-winged species whose larvae develop in open boil-like lesions in the skin of humans, many domestic animals, and some fowl. It is a very serious and damaging cattle parasite and frequently attacks small children in Central and South America. Its eggs are laid on the legs or abdomen of another in …

human botfly myiasis
Synonym for dermatobiasis ... Infection of man and animals with larvae of the fly Dermatobia hominis. ... Synonym: human botfly myiasis. ... (05 Mar 2000) ...

human chorionic gonadotrophin
<hormone, tumour marker> A hormone that is produced by the developing placenta and by the fertilized egg after implantation in the uterine wall. ... This hormone is measured in the blood to determine pregnancy. Human chorionic gonadotrophin increases in quantity through the first trimester of pregnancy and begin to taper off after 85 days. ... …

human chorionic gonadotropin
A human hormone made by chorionic cells (in the foetal part of the placenta), hcg is directed at the gonads and stimulates them. Hcg becomes detectable (by immunologic means) within days of fertilization and forms the foundation of the common pregnancy tests. The level of hcg in maternal serum also enters as one component in the double and the trip …

human chorionic somatomammotropin
human placental lactogen ...

human clinical trial
<pharmacology> Controlled clinical studies in human volunteers to test the safety and efficacy of pharmaceutical candidates. ... There are usually three distinct phases of human clinical testing: Phases I, II, and III. ... Phase I trials are safety studies of volunteers, usually healthy controls. Phase II trials are studies to confirm safety an …

human cytomegalovirus
<virology> A group of viruses within the subfamily Cytomegalovirus (Betaherpesvirinae) (of the family Herpesviridae) which infects human beings. ... (09 Oct 1997) ...

human development
Continuous sequential changes which occur in the physiological and psychological functions during the individual's life. ... (12 Dec 1998) ...

human diploid cell rabies vaccine
Synonym for human diploid cell vaccine ... An iodinated virus vaccine used for protection against rabies vaccine usually prepared in the human diploid cell WI-38. ... Synonym: human diploid cell rabies vaccine. ... (05 Mar 2000) ...

human diploid cell vaccine
An iodinated virus vaccine used for protection against rabies vaccine usually prepared in the human diploid cell WI-38. ... Synonym: human diploid cell rabies vaccine. ... (05 Mar 2000) ...

human ecology
The relations of persons to their total (biologic and social) environment. ... (05 Mar 2000) ...

human ehrlichiosis
A form of ehrlichiosis that presents clinically as a undifferentiated acute febrile illness characterised by fever, chills, diarrhoea, and headache, following tick bite(s), probably by the Lone Star Tick, Amblyomma americanum. Caused by Ehrlichia chaffeensis. First described in 1987. (Thought to be predominantly a monocytic form of ehrlichiosis.)
human embryo lung cell
<cell culture> Diploid, untransformed cells from the lungs of human embryos which are used to make vaccines against certain viruses (such as rabies). ... (09 Oct 1997) ...

human engineering
The science of designing, building or equipping mechanical devices or artificial environments to the anthropometric, physiological, or psychological requirements of the people who will use them. ... (12 Dec 1998) ...

human fibrin foam
A dry artificial sponge of human fibrin prepared by clotting with thrombin a foam of a solution of human fibrinogen; the clotted foam is dried from the frozen state and heated; used as a topical anticoagulant. ... (05 Mar 2000) ...

human gamma globulin
A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature. ... Synonym: human normal immunoglobulin. ... (05 Mar 20 …

human gene therapy
<molecular biology, technique> Insertion of normal DNA directly into cells to correct a genetic defect. ... (09 Oct 1997) ...

human genetics
The study of the genetic aspects of humans as a species. ... Compare: medical genetics. ... (05 Mar 2000) ...

human genome
The full collection of genes in a human being. ... (12 Dec 1998) ...

human genome initiative
<molecular biology> Collective name for several projects begun in 1986 by the Department of Energy to create an ordered set of DNA segments from known chromosomal locations, develop new computational methods for analysing genetic map and DNA sequence data, and develop new techniques and instruments for detecting and analysing DNA. ... This ini …

human genome project
<molecular biology> A worldwide project to determine the DNA sequence of all the DNA in humans, funded primarily by the U.S. Department of Energy (DOE), the U.S. National Institutes of Health (NIH), the European Commission (EC), and the pharmaceutical and biotechnology industries. ... The project will be completed in stages, beginning with a g …

human granulocytic ehrlichiosis
A form of ehrlichiosis in a patient with a history of tick bite. Characterised by leukopenia, thrombocytopenia, and mild liver damage. (Thought to be predominantly a granulocytic form of ehrlichiosis.) The species of Ehrlichia that is the agent of this disease is unknown at present. ... (05 Mar 2000) ...

human herpesvirus 1
Herpes simplex virus, type 1. ... See: herpes simplex. ... (05 Mar 2000) ...

human herpesvirus 2
Herpes simplex virus, type 2. ... See: herpes simplex. ... (05 Mar 2000) ...

human herpesvirus 3
Synonym for varicella-zoster virus ... A herpesvirus, morphologically identical to herpes simplex virus, that causes varicella (chickenpox) and herpes zoster in man; varicella results from a primary infection with the virus; herpes zoster results from secondary invasion by the same virus or by reactivation of infection which in many instances has be …

human herpesvirus 4
Synonym for Epstein-Barr virus ... <virology> Species of Herpetoviridae that is responsible for infectious mononucleosis (glandular fever). Discovered in 1964, this virus has been associated with Burkitt's lymphoma in South African children and with nasopharyngeal carcinoma in Asian populations. ... (27 Sep 1997) ...

human herpesvirus 5
Synonym for cytomegalovirus ... <virology> Probably the most widespread of the Herpetoviridae group. ... Infected cells enlarge and have a characteristic inclusion body (composed of virus particles) in the nucleus. Causes disease only in utero (leading to abortion or stillbirth or to various congenital defects), although can be opportunistic in …

human herpesvirus 6
A recently discovered human herpesvirus that was found in certain lymphoproliferative disorders, replicates in a number of different types of leukocytes, and is associated with the childhood disease roseola (exanthema subitum). ... (05 Mar 2000) ...

human herpesvirus 7
This virus has recently been discovered in association with human lymphocytes; however, a causal relationship to any known disease has not been determined. ... (05 Mar 2000) ...

human immunodeficiency virus
<virology> A type of retrovirus (human immunodeficiency virus) that is responsible for the fatal illness acquired immunodeficiency syndrome. Two strains have been identified. ... Type 1: the retrovirus recognised as the agent that induces AIDS. ... Type 2: a virus closely related to HIV-1 that also leads to immune suppression. HIV-2 is not as v …

human leukaemia-associated antigens
Antigen's on the surface of leukaemic cells which seem not to be present on the surfaces of the same type of normal cells; the myeloblast antigen of acute myelogenous leukaemia found in chronic myelogenous leukaemia is thought to be associated with a 'blastic' transformation. ... (05 Mar 2000) ...

human leukocyte antigen
<immunology> A genetic fingerprint on white blood cells and platelets, composed of proteins that play a critical role in activating the bodys immune system to respond to foreign organisms. ... Acronym: HLA ... (16 Dec 1997) ...

human leukocyte-associated antigens
Proteins on the outer part of body cells that help fight illness. These proteins vary from person to person. Scientists think that people with certain types of HLA antigens are more likely to develop insulin-dependent diabetes.The HLA antigens are also responsible for histocompatibility reactions. ... (09 Oct 1997) ...

human lymphocyte antigen
A system designation for the gene products of at least four linked loci (A, B, C, and D) and a member of subloci on the sixth human chromosome which have been shown to have a strong influence on human allotransplantation, transfusions in refractory patients, and certain disease associations; more than 50 alleles are recognised, most of which are at …

human measles immune serum
Obtained from the blood of a healthy person who has survived an attack of measles. ... Synonym: measles convalescent serum. ... (05 Mar 2000) ...

human menopausal gonadotropin
A hormone of pituitary originally obtained from the urine of postmenopausal women now produced synthetically; used to induce ovulation. ... See: menotropins. ... (05 Mar 2000) ...

human normal immunoglobulin
Synonym for human gamma globulin ... A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature. ... Synonym: human …

human papilloma virus
<virology> A disease caused by the human papilloma virus characterised by a soft wart-like growth on the genitalia (for example penis, vulva). In adults this infection is most commonly transmitted sexually. Genital warts are very common and are increasing in incidence. ... Safe sex practices, such as using condoms can help decrease the risk of …

human pertussis immune serum
The sterile serum prepared from the pooled blood of healthy adult human beings who have received repeated courses of phase I pertussis vaccine; administered intravenously or intramuscularly for the prophylaxis or treatment of whooping cough. ... (05 Mar 2000) ...

human plasma protein fraction
A sterile solution of selected proteins derived from the blood plasma of adult human donors, containing 4.5 to 5.5 g of protein per 100 ml, of which 83 to 90% is albumin and the remainder is alpha-and beta-globulins; used as a blood volume supporter. ... (05 Mar 2000) ...

human rights
The rights of the individual to cultural, social, economic, and educational opportunities as provided by society, e.g., right to work, right to education, and right to social security. ... (12 Dec 1998) ...