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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

leukokeratosis
Rarely used term for leukoplakia. ... (05 Mar 2000) ...

leukokinetic
Pertaining to leukokinetics. ... Origin: Leukocyte + G. Kinetikos, of motion, fr. Kineo, to move ... (05 Mar 2000) ...

leukokinetics
The study of the formation, circulation, and fate of leukocyte, usually by use of a radioactive tracer. ... Origin: Leukocyte + G. Kinetikos, of or for putting in motion ... (05 Mar 2000) ...

leukokininase
<enzyme> Membrane enzyme which acts on bound leukokinin-s cleaving it at amino end of threonine between residues 288 and 289, releasing free, active tuftsin ... Registry number: EC 3.4.- ... (26 Jun 1999) ...

leukokoria
See: leukocoria. ... (05 Mar 2000) ...

leukokraurosis
Synonym for kraurosis vulvae ... An atrophic disease affecting the female external genitalia, most often of older women, resulting in drying and shriveling of the parts, and marked by leukoplakic patches on the mucosa, itching, dyspareunia, dysuria, and soreness. It occurs most commonly as a result of lichen sclerosus et atrophicus of the vulva, but …

leukolymphosarcoma
<tumour> Obsolete term for malignant lymphoma. ... (05 Mar 2000) ...

leukolysin
Synonym for leukocytolysin ... Any substance (including lytic antibody) that causes dissolution of leukocytes. ... Synonym: leukolysin. ... (05 Mar 2000) ...

leukolysis
Synonym for leukocytolysis ... Dissolution or lysis of leukocytes. ... Synonym: leukolysis. ... Origin: Leukocyte + G. Lysis, dissolution ... (05 Mar 2000) ...

leukolytic
Synonym for leukocytolytic ... Pertaining to, causing, or manifesting leukocytolysis. ... Synonym: leukolytic. ... (05 Mar 2000) ...

leukoma
A dense, opaque, white opacity of the cornea. ... Origin: G. Whiteness, a white spot in the eye, fr. Leukos, white ... Adherent leukoma, a cicatrix of the cornea to which a portion of the iris is attached. ... (05 Mar 2000) ...

leukomalacia, periventricular
A disease of premature or newborn infants hypoxic and ischemic in nature and leading to infarction of brain white matter and cerebral ventricle enlargement. ... (12 Dec 1998) ...

leukomatous
Denoting leukoma. ... (05 Mar 2000) ...

leukomyelitis
An inflammatory process involving the white matter of the spinal cord. ... Necrotizing haemorrhage leukomyelitis, the pathological substrate responsible for the clinical disorder of acute necrotizing myelitis. ... (05 Mar 2000) ...

leukomyelopathy
Any systemic disease involving the white matter or the conducting tracts of the spinal cord. ... Origin: Leuko-+ G. Myelos, marrow, + pathos, suffering ... (05 Mar 2000) ...

leukon
The total mass of circulating leukocytes as well as the cells and leukopoietic cells from which it originates. ... (05 Mar 2000) ...

leukonecrosis
Synonym: white gangrene. ... Origin: Leuko-+ G. Nekrosis, deadness ... (05 Mar 2000) ...

leukonychia
The occurrence of white spots or patches under the nails, of unknown cause; the decoloration may be total or in the form of lines (striate or transverse leukonychia) or dots (punctate leukonychia). ... Synonym: achromia unguium, canities unguium, leukopathia unguis. ... Origin: Leuko-+ G. Onyx (onych-), nail ... Apparent leukonychia, pallor of the nai …

leukopathia
Leukopathy ... Synonym: leukoderma. ... Origin: Leuko-+ G. Pathos, disease ... (05 Mar 2000) ...

leukopathia unguis
Synonym for leukonychia ... The occurrence of white spots or patches under the nails, of unknown cause; the decoloration may be total or in the form of lines (striate or transverse leukonychia) or dots (punctate leukonychia). ... Synonym: achromia unguium, canities unguium, leukopathia unguis. ... Origin: Leuko-+ G. Onyx (onych-), nail ... Apparent leu …

leukopedesis
The movement of white blood cells (especially polymorphonuclear leukocytes) through the walls of capillaries and into the tissues. ... Origin: Leuko-+ G. Pedesis, a leaping ... (05 Mar 2000) ...

leukopenia
Abnormal decrease in the number of white blood cells. ... (16 Dec 1997) ...

leukopenic
Pertaining to leukopenia. ... (05 Mar 2000) ...

leukopenic factor
A principle obtained by Menkin from inflammatory exudates; it causes leukopenia when injected into normal animals. ... (05 Mar 2000) ...

leukopenic index
A significant decrease in the white blood count after ingestion of food to which a patient is hypersensitive, a count made during the normal fasting state being used as the basis for evaluation of the postprandial count. ... (05 Mar 2000) ...

leukopenic leukaemia
A form of lymphocytic, granulocytic, or monocytic leukaemia in which the total number of white blood cells in the circulating blood is in the normal range, or may be diminished to various levels that are significantly less than normal. ... (05 Mar 2000) ...

leukophlegmasia
Synonym: lymphatic oedema. ... Origin: Leuko-+ phlegmasia ... (05 Mar 2000) ...

leukophlegmasia dolens
Synonym for phlegmasia alba dolens ... An extreme edematous swelling of the leg following childbirth, due to thrombosis of the iliofemoral veins. ... Synonym: leukophlegmasia dolens, milk leg, puerperal phlebitis, thrombotic phlegmasia, white leg. ... (05 Mar 2000) ...

leukoplakia
Circumscribed, firmly attached, thick white patches on the tongue and other mucous membranes (genitalia), often occurring as a pre-cancerous growth. Leukoplakia develops on the oral mucosa in response to chronic irritation (for example ill-fitting dentures, smoking, chewing tobacco). ... (27 Sep 1997) ...

leukoplakia vulvae
A clinical term for hyperkeratotic white patches of the vulvar epithelium; biopsy is necessary for specific diagnosis. ... Synonym: leukoplakic vulvitis. ... (05 Mar 2000) ...

leukoplakia, hairy
Epithelial hyperplasia of the oral mucosa associated with epstein-barr virus and found almost exclusively in persons with HIV infection. The lesion consists of a white patch that is often corrugated or hairy. ... (12 Dec 1998) ...

leukoplakia, oral
A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of epstein-barr virus is present, the condition is called hairy leukoplakia (leukoplakia, hairy). ... (12 Dec 1998) ...

leukoplakic vulvitis
Synonym for leukoplakia vulvae ... A clinical term for hyperkeratotic white patches of the vulvar epithelium; biopsy is necessary for specific diagnosis. ... Synonym: leukoplakic vulvitis. ... (05 Mar 2000) ...

leukopoiesis
The production of leukocytes. They are formed partially in the bone marrow (granulocytes, monocytes and a few lymphocytes) and partially in lymphatic tissue (lymphocytes and plasma cells). (guyton & hall, textbook of medical physiology, 9th ed) ... (12 Dec 1998) ...

leukopoietic
Pertaining to or characterised by leukopoiesis, as manifested by portions of the bone marrow and reticuloendothelial and lymphoid tissues, which form (respectively) the granulocytes, monocytes, and lymphocytes. ... (05 Mar 2000) ...

leukoprotease
An ill-defined proteolytic enzyme product of polynuclear leukocytes, formed in an area of inflammation, that causes liquefaction of dead tissue. ... (05 Mar 2000) ...

leukoriboflavin
The colourless nonfluorescing dihydro compound formed by the reduction of riboflavin. ... (05 Mar 2000) ...

leukorrhagia
Synonym: leukorrhoea. ... Origin: Leuko-+ G. Rhegnymi, to burst forth ... (05 Mar 2000) ...

leukorrhoea
A whitish, viscid discharge from the vagina and uterine cavity. ... Origin: Gr. Rhoia = flow ... (18 Nov 1997) ...

leukorrhoeal
Relating to or characterised by leukorrhoea. ... (05 Mar 2000) ...

leukosarcoma
<tumour> Obsolete term for malignant lymphoma. ... (05 Mar 2000) ...

leukosarcomatosis
An obsolete term for a condition characterised initially by numerous widespread nodules or masses of lymphosarcoma, and the subsequent presence of similar cells in the circulating blood as in leukosarcoma. ... Abnormal proliferation of one or more of the leukopoietic tissues; the term includes myelosis, certain forms of reticuloendotheliosis, and ly …

leukosialin
<protein> CD43, (sialophorin) Widely distributed membrane associated mucin, the major sialoglycoprotein of thymocytes and mature T-cells. Transmembrane protein with extensive O linked glycosylation (75-85 oligosaccharides on the 239 residue extracellular domain). Extends at least 45nm beyond plasma membrane. Similar but not homologous to epis …

leukosis virus, avian
The type species of avian type c retroviruses (retroviruses type c, avian) producing latent or manifest lymphoid leukosis in fowl. ... (12 Dec 1998) ...

leukostasis
Abnormal intravascular leukocyte aggregation and clumping often seen in leukaemia patients. The brain and lungs are the two most commonly affected organs. This acute syndrome requires aggressive cytoreductive modalities including chemotherapy and/or leukophoresis. It is differentiated from leukaemic infiltration which is a neoplastic process where …

leukosulphakinin
<protein> Cockroach peptide hormones, that affect gut motility. Related to gastrin. ... (18 Nov 1997) ...

leukotactic
Synonym for leukocytotactic ... Pertaining to, characterised by, or causing leukocytotaxia. ... Synonym: leukocytactic, leukotactic. ... (05 Mar 2000) ...

leukotaxia
Synonym for leukocytotaxia ... 1. The active ameboid movement of leukocytes, especially the neutrophilic granulocytes, either toward (positive leukocytotaxia) or away from (negative leukocytotaxia) certain microorganisms as well as various substances frequently formed in inflamed tissue. ... 2. The property of attracting or repelling leukocytes. ... S …

leukotaxine
A cell-free nitrogenous material prepared from injured, acutely degenerating tissue and from inflammatory exudates. ... (05 Mar 2000) ...

leukotaxis
Synonym for leukocytotaxia ... 1. The active ameboid movement of leukocytes, especially the neutrophilic granulocytes, either toward (positive leukocytotaxia) or away from (negative leukocytotaxia) certain microorganisms as well as various substances frequently formed in inflamed tissue. ... 2. The property of attracting or repelling leukocytes. ... S …

leukotic
Pertaining to, characterised by, or manifesting leukosis. ... (05 Mar 2000) ...

leukotome
An instrument for performing leukotomy. ... (05 Mar 2000) ...

leukotomy
<procedure> Incision into the white matter of the frontal lobe of the brain. ... Origin: Leuko-+ G. Tome, a cutting ... (05 Mar 2000) ...

leukotoxin
Synonym for leukocytotoxin ... Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin. ... Synonym: leukotoxin. ... Origin: Leukocyte + G. Toxikon, poison ... (05 Mar 2000) ...

leukotrichia
Whiteness of the hair. ... Origin: Leuko-+ G. Thrix, hair ... (05 Mar 2000) ...

leukotrichia annularis
Synonym for ringed hair ... A rare condition in which the hair shows alternate pigmented and bright segments, the latter due to air cavities within the cortex. ... Synonym: leukotrichia annularis, pili annulati, thrix annulata, trichonosus versicolor. ... (05 Mar 2000) ...

leukotrichous
Having white hair. ... (05 Mar 2000) ...

leukotriene
Any of a group of hormonesderived from arachidonate (arachidonic acid).They are thought to mediate the allergic response that causes lungconstriction and muscle contraction in asthma. ... (09 Oct 1997) ...

leukotriene a4
(2s-(2 alpha,3 beta(1e,3e,5z,8z)))-3-(1,3,5,8-tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-hpete via the stereospecific removal of a proton at c-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., leukotriene b4 and cysteinyl-leukotrienes. Alter …

leukotriene A4 hydrolase
<enzyme> Catalyses hydrolysis of leukotriene a4 to leukotriene b4; mw 68,000-70,000 ... Registry number: EC 3.3.2.- ... Synonym: leukotriene a4 aminopeptidase ... (26 Jun 1999) ...

leukotriene b4
<chemical> (s-(r*,s*-(e,z,e,z)))-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid. The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centreed free radicals, arachidonic acid release, and metabolism). ... Chemical name: 6,8,10,14-Eicosatetraenoic acid …

leukotriene B4 6-isomerase
<enzyme> From rat kidney homogenates ... Registry number: EC 5.2.- ... (26 Jun 1999) ...

leukotriene B4 reductase
<enzyme> Converts leukotriene b4 (5s,12r-dihydroxyeicosoletra-6,8,10,14-enoic acid) to dihydro ltb4 (5s,12r-10,11-dihydroeicosatri-6,8,14-enoic acid), requires NADPH, ca and mg ... Registry number: EC 1.3.1.- ... (26 Jun 1999) ...

leukotriene c4
<chemical> (r-(r*,s*-(e,e,z,z))))-n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-n-l-gamma-glutamyl-l-cysteinyl)glycine. The conjugation product of leukotriene a4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitised lung tissue. It stimulates mucus se …

leukotriene d4
<chemical> (r-(r*,s*-(e,e,z,z)))-n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-l-cysteinyl)glycine. One of the biologically active principles of srs-a. It is generated from leukotriene c4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of …

leukotriene D4 dipeptidase
<enzyme> Converts leukotriene d4 to leukotriene e4 ... Registry number: EC 3.4.13.- ... Synonym: ld4 dipeptidase ... (26 Jun 1999) ...

leukotriene e4
<chemical> (5s-(5r*,6s*(s*),7e,9e,11z,14z))-6-((2-amino-2-carboxyethyl)thio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid. A biologically active principle of srs-a that is formed from leukotriene d4 via a peptidase reaction that removes the glycine residue. The biological actions of lte4 are similar to ltc4 and ltd4. ... Chemical name: 7,9,11,14- …

leukotriene-C4 synthase
<enzyme> From particulate fraction of rat basophil leukaemia homogenates; not sensitive to inhibitors of most soluble glutathione s-transferases ... Registry number: EC 2.5.1.37 ... Synonym: leukotriene c synthase, leukotriene a4-glutathione s-leukotrienyltransferase, leukotriene c4 synthetase, glutathione s-transferase II, gst-ii ... (26 Jun 19 …

leukotrienes
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascu …

Leukovirus
A former genus composed of the RNA tumour viruses now included in the family Retroviridae. ... (05 Mar 2000) ...

leupeptin
A peptide (N-acetylleucylleucylarginyl) from Streptomyces species that inhibits cathepsin B, papain, trypsin, plasmin, and cathepsin D. ... (05 Mar 2000) ...

leupeptin acid reductase
<enzyme> Converts leupeptin acid (acetyl-l-leu-l-leu-l-arg) into leupeptin (acetyl-l-leu-l-leu-l-arginal); requires ATP and NADPH ... Registry number: EC 1.2.1.- ... (26 Jun 1999) ...

leupeptin acid synthetase
<enzyme> ATP essential for reaction ... Registry number: EC 6.3.2.- ... (26 Jun 1999) ...

leupeptinase
<enzyme> Serine protease active at neutral pH; inhibited by isoflurophate and phenylmethylsulfonyl fluoride ... Registry number: EC 3.4.21.- ... (26 Jun 1999) ...

leupeptins
<chemical> A group of acylated oligopeptides produced by actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, kallikrein, papain and the cathepsins. ... Pharmacological action: protease inhibitors. ... (12 Dec 1998) ...

leuprolide
<chemical> A synthetic nonapeptide agonist analog of gonadorelin. It is used in the treatment of advanced prostatic cancer, fibrocystic disease of the breast, and leiomyoma of the uterus. ... Pharmacological action: antineoplastic agent, hormonal. ... Chemical name: Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamid …

leuprolide acetate
A synthetic nonapeptide analog of naturally occurring gonadotropin-releasing hormone; used in the palliative treatment of advanced prostatic cancer. ... (05 Mar 2000) ...

leurocristine
Synonym for vincristine sulfate ... A dimeric alkaloid obtained from Vinca rosea; its antineoplastic activity is similar to that of vinblastine, but no cross-resistance develops between these two agents, and it is more useful than vinblastine in lymphocytic lymphosarcoma and acute leukaemia. ... Synonym: leurocristine. ... (05 Mar 2000) ...

Lev, Maurice
<person> U.S. Pathologist, *1908. ... See: Lev's disease, Lev's syndrome. ... (05 Mar 2000) ...

Lev's disease
Synonym for Lev's syndrome ... <syndrome> Bundle branch block in a patient with normal myocardium and normal coronary arteries resulting from fibrosis or calcification including the conducting system; affects the membranous septum, the apex of the muscular septum, and often the mitral and aortic valve rings. ... Synonym: Lev's disease. ... (05 M …

Lev's syndrome
<syndrome> Bundle branch block in a patient with normal myocardium and normal coronary arteries resulting from fibrosis or calcification including the conducting system; affects the membranous septum, the apex of the muscular septum, and often the mitral and aortic valve rings. ... Synonym: Lev's disease. ... (05 Mar 2000) ...

Levaditi stain
<technique> A silver nitrate stain for blackening spirochetes in tissue sections. ... (05 Mar 2000) ...

Levaditi, Constantin
<person> Roumanian bacteriologist in Paris, 1874-1928. ... See: Levaditi stain. ... (05 Mar 2000) ...

levallorphan
<chemical> An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. …

levallorphan tartrate
1-N-Allyl-3-hydroxymorphinan tartrate;the N-allyl analog of levorphanol, antagonistic to the actions of narcotic analgesics; used in the treatment of respiratory depression due to overdosage of narcotics. ... (05 Mar 2000) ...

levamisole
<chemical> An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and t-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, …

levan
Synonym for fructosan ... A polysaccharide of fructose (e.g., inulin) containing small amounts of other sugars; present in certain tubers. ... Synonym: levan, levulan, levulin, levulosan, polyfructose. ... (05 Mar 2000) ...

levan fructotransferase
<enzyme> Forms difructose 2,6'-6,2' dianhydride ... Registry number: EC 2.4.1.- ... (26 Jun 1999) ...

levansucrase
<enzyme> An enzyme catalyzing transfer of the fructose moiety of sucrose to polyfructose (a levan), releasing d-glucose. ... (05 Mar 2000) ...

levarterenol
Synonym: norepinephrine. ... (05 Mar 2000) ...

levarterenol bitartrate
norepinephrine bitartrate ...

levator anguli oris
<anatomy, muscle> Origin, canine fossa of maxilla; insertion, orbicularis oris and skin at angle of mouth; action, raises angle of mouth; nerve supply, facial. ... Synonym: musculus levator anguli oris, musculus caninus, musculus triangularis labii superioris. ... (05 Mar 2000) ...

levator ani muscle
<anatomy> Formed by pubococcygeus and iliococcygeus muscles; origin, posterior body of pubis, tendinous arch of the levator ani, and spine of ischium; insertion, anococcygeal ligament, sides of the lower part of the sacrum and of coccyx; action, resists prolapsing forces and draws the anus upward following defecation; supports the pelvic visc …

levator cushion
The bulge in the lateral wall of the nasopharynx, below the opening of the auditory tube, produced by the levator veli palatini muscle. ... Synonym: torus levatorius, levator swelling. ... (05 Mar 2000) ...

levator hernia
Synonym for perineal hernia ... A hernia protruding through the pelvic diaphragm. ... Synonym: levator hernia, pudendal hernia. ... (05 Mar 2000) ...

levator labii superioris
<anatomy, muscle> Origin, maxilla below infraorbital foramen; insertion, orbicularis oris of upper lip; action, elevates upper lip; nerve supply, facial. ... Synonym: musculus levator labii superioris, caput infraorbitale quadrati labii superioris, elevator muscle of upper lip. ... (05 Mar 2000) ...

levator muscle of thyroid gland
A fasciculus occasionally passing from the thyrohyoid muscle to the isthmus of the thyroid gland. ... Synonym: musculus levator glandulae thyroideae, elevator muscle of thyroid gland, Soemmerring's muscle. ... (05 Mar 2000) ...

levator palati muscle
Synonym for levator veli palatini ... <anatomy, muscle> Origin, apex of petrous portion of temporal bone and lower part of cartilaginous auditory (eustachian) tube; insertion, aponeurosis of soft palate; action, raises soft palate; through the expansion of its fleshy belly during contraction, it helps to 'push' open the auditory tube; nerve su …

levator palpebrae superioris
<anatomy, muscle> Origin, orbital surface of the lesser wing of the sphenoid, above and anterior to the optic canal; insertion, skin of eyelid, tarsal plate, and orbital walls, by medial and lateral expansions of the aponeurosis of insertion; action, raises the upper eyelid; nerve supply, oculomotor. ... Synonym: musculus levator palpebrae sup …

levator prostatae muscle
<anatomy> In the male, the most medial fibres of the levator ani (pubococcygeus) muscle that extend from the pubis into the fascia of the prostate. ... Synonym: musculus levator prostatae, elevator muscle of prostate. ... (05 Mar 2000) ...