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 mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


leukaemia, feline
A neoplastic disease of cats frequently associated with feline leukaemia virus infection. ... (12 Dec 1998) ...

leukaemia, hairy cell
A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukaemia; it is characterised by an insidious onset, splenomegaly, anaemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of 'hairy' or 'flagellated' cells in the blood and bone marrow. ... (12 Dec 1998) ...

leukaemia, lymphocytic
Leukaemia associated with hyperplasia and overactivity of the lymphoid tissue. There are increased numbers of circulating malignant lymphocytes and lymphoblasts. ... (12 Dec 1998) ...

leukaemia, masT-cell
A disorder characterised by the presence of large numbers of tissue mast cells in the peripheral blood. ... (12 Dec 1998) ...

leukaemia, megakaryocytic, acute
Nonlymphocytic leukaemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. Myelofibrosis or increased bone marrow reticulin is common. ... (12 Dec 1998) ...

leukaemia, myelocytic, acute
Progressive, malignant disease of the myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate. ... (12 Dec 1998) ...

leukaemia, myeloid
Form of leukaemia characterised by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites. ... (12 Dec 1998) ...

leukaemia, nonlymphocytic, acute
Acute leukaemia distinguished from acute lymphocytic leukaemia (all) by the morphology of the marrow and blood leukaemic cells. Cytoplasmic granules are usually present and the nucleus is usually large and irregular. Anll is more common in adults than all and occurs at any age. ... (12 Dec 1998) ...

leukaemia, smoldering
A condition in which the bone marrow does not function normally. It does not produce enough blood cells. This condition may progress and become acute leukaemia. Smoldering leukaemia also is called myelodysplastic syndrome or preleukaemia. ... (12 Dec 1998) ...

leukaemic
Pertaining to, or having the characteristics of, any form of leukaemia. ... (05 Mar 2000) ...

leukaemic hyperplastic gingivitis
Enlarged gingiva due to infiltration of leukaemic cells and infection from local factors in the face of diminshed host response. ... (05 Mar 2000) ...

leukaemic infiltration
A pathologic change in leukaemia in which leukaemic cells permeate various organs at any stage of the disease. All types of leukaemia show various degrees of infiltration, depending upon the type of leukaemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myel …

leukaemic leukaemia
A redundant term sometimes used to emphasize the occurrence of abundant numbers of leukaemic cells in the circulating blood; this classic form of leukaemia is usually termed simply leukaemia. ... (05 Mar 2000) ...

leukaemic myelosis
Synonym for granulocytic leukaemia ... <haematology, tumour> A form of leukaemia characterised by an uncontrolled proliferation of myelopoietic cells in the bone marrow and in extramedullary sites, and the presence of large numbers of immature and mature granulocytic forms in various tissues (and organs) and in the circulating blood. ... The to …

leukaemic reticuloendotheliosis
An obsolete term for hairy cell leukaemia. ... (05 Mar 2000) ...

leukaemic reticulosis
Synonym for monocytic leukaemia ... Cancer of the blood due to proliferation of cells of the monocyte series. ... Origin: Gr. Haima = blood ... (13 Nov 1997) ...

leukaemic retinitis
See: leukaemic retinopathy. ... (05 Mar 2000) ...

leukaemic retinopathy
Appearance of the retina in all types of leukaemia, characterised by engorgement and tortuosity of veins, scattered haemorrhages, and oedema of the retina and disk. ... (05 Mar 2000) ...

leukaemogenesis
The development of leukaemia. ... (13 Nov 1997) ...

leukanaemia
Former term for erythroleukaemia. ... Origin: Leukaemia + anaemia ... (05 Mar 2000) ...

leukapheresis
The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor. ... (12 Dec 1998) ...

leukasmus
Synonym: vitiligo. ... Origin: G. Leukasmos, a growing white ... (05 Mar 2000) ...

leukemia
Synonym for leukaemia ... <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is clas …

leukemid
Any non-specific type of cutaneous lesion that is frequently associated with leukaemia (as a feature of the syndrome), but is not a localised accumulation of leukaemic cells; e.g., petechiae, vesicles, wheals, bullae, haematomas, and the lesions of exfoliative dermatitis and herpes zoster. ... Origin: Leuko-+ G. Haima, blood, + id ... (05 Mar 2000)
leukemogen
Any substance or entity (e.g., benzene, ionizing radiation) considered to be a causal factor in the occurrence of leukaemia. ... (05 Mar 2000) ...

leukemogenesis
The causation (or induction), development, and progression of a leukaemic disease. ... Origin: Leukaemia + G. Genesis, production ... (05 Mar 2000) ...

leukemogenic
Pertaining to the causation, induction, and development of leukaemia; manifesting the ability to cause leukaemia. ... (05 Mar 2000) ...

leukemoid
Resembling leukaemia in various signs and symptoms, especially with reference to changes in the circulating blood. ... See: leukemoid reaction. ... Origin: Leukaemia + G. Eidos, resemblance ... (05 Mar 2000) ...

leukemoid reaction
A benign blood picture resembling leukaemia. For example, in infectious mononucleosis. ... (12 Dec 1998) ...

leukin
A thermostable bactericidal substance extracted from leukocytes. ... Synonym: leucin. ... Origin: Leukocyte + -in ... (05 Mar 2000) ...

leuko-
<prefix> Prefix meaning white. ... (12 Dec 1998) ...

leukoagglutinin
An antibody that agglutinates white blood cells. ... (05 Mar 2000) ...

leukobilin
Synonym: white bile. ... Origin: Leuko-+ L. Bilis, bile ... (05 Mar 2000) ...

leukoblast
An immature white blood cell that is transitional between the lymphoidocyte (or the myeloblast of Naegeli and Downey) and the promyelocyte; the cytoplasm is polychromatophilic or slightly acidophilic and, as compared with the lymphoidocyte, the nuclear network of chromatin is thicker and the nucleoli less distinct. ... Synonym: proleukocyte. ... Orig …

leukoblastosis
A general term for the abnormal proliferation of leukocytes, especially that occurring in myelocytic and lymphocytic leukaemia. ... (05 Mar 2000) ...

leukochloroma
<tumour> Synonym: myelocytomatosis. ... Origin: Leuko-+ G. Chloros, green, + -oma, tumour ... (05 Mar 2000) ...

leukocidin
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells. ... Origin: Leukocyte + L. Caedo, to kill ... (05 Mar 2000) ...

leukocidins
Substances that are toxic to leukocytes. Specifically exotoxins produced by some pathogenic staphylococci and streptococci that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms. ... (12 Dec 1998) ...

leukocoria
Reflection from a white mass within the eye giving the appearance of a white pupil. ... Synonym: leukokoria, white pupillary reflex. ... Origin: Leuko-white, + G. Kore, pupil ... (05 Mar 2000) ...

leukocytactic
Synonym for leukocytotactic ... Pertaining to, characterised by, or causing leukocytotaxia. ... Synonym: leukocytactic, leukotactic. ... (05 Mar 2000) ...

leukocytal
Synonym for leukocytic ... Pertaining to or characterised by leukocytes. ... Synonym: leukocytal. ... (05 Mar 2000) ...

leukocytaxia
Synonym for leukocytotaxia ... 1. The active ameboid movement of leukocytes, especially the neutrophilic granulocytes, either toward (positive leukocytotaxia) or away from (negative leukocytotaxia) certain microorganisms as well as various substances frequently formed in inflamed tissue. ... 2. The property of attracting or repelling leukocytes. ... S …

leukocyte
Synonym for white blood cell ... <haematology> White corpuscles in the blood. They are spherical, colourless and nucleated masses involved with host defenses. ... Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. …

leukocyte adherence assay test
A test to detect the ability of leukocytes to adhere to bacteria, performed in vitro using nylon fibres to measure adherence. ... (05 Mar 2000) ...

leukocyte adherence inhibition test
Test for cell-mediated antitumour immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumours of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumour-bearing patients bloc …

leukocyte adhesion deficiency
An inherited disorder (autosomal recessive) in which there is a defective CD18 adherence complex that disturbs leukocyte chemotaxis. It is characterised by recurrent bacterial infections and impaired wound healing. ... (05 Mar 2000) ...

leukocyte bactericidal assay test
A test of leukocytes to determine their ability to kill a culture of live bacteria. ... (05 Mar 2000) ...

leukocyte common antigen
Family of glycoproteins found on most leukocytes and absent from other cell types. These cell surface antigens can comprise up to 10% of the membrane proteins. ... (05 Mar 2000) ...

leukocyte count
A white blood cell (WBC) count. ... (12 Dec 1998) ...

leukocyte cream
Synonym for buffy coat ... <haematology> Thin yellow white layer of leucocytes on top of the mass of red cells when whole blood is centrifuged. ... (18 Nov 1997) ...

leukocyte disorders
Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells. ... (12 Dec 1998) ...

leukocyte elastase
<enzyme> An enzyme that catalyses the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of ala and val, with greater specificity for ala. ... Registry number: EC 3.4.21.37 ... (12 Dec 1998) ...

leukocyte esterase
<enzyme> The presence of leukocyte esterase is indirect evidence for the presence of white blood cells in the urine. The standard urinalysis dip test allows for the quick determination of leukocyte esterase presence via a colour reaction on a urine test strip. A positive test indicates a urinary tract infection. ... (27 Sep 1997) ...

leukocyte inclusions
Synonym for Dohle bodies ... Discrete round or oval body's ranging in diameter from just visible to 2 um, which stain sky blue to gray blue with Romanowsky stains, found in neutrophils of patients with infections, burns, trauma, pregnancy, or cancer. ... Synonym: Dohle inclusions, leukocyte inclusions. ... (05 Mar 2000) ...

leukocyte interferon
Synonym for interferon-alpha ... <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. ... It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral …

leukocyte transfusion
The transfer of leukocytes from a donor to a recipient or reinfusion to the donor. ... (12 Dec 1998) ...

leukocytes
Cells that help the body fight infections and other diseases. Also called white blood cells (wbcs). ... (12 Dec 1998) ...

leukocytes, mononuclear
Mature lymphocytes and monocytes transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules. ... (12 Dec 1998) ...

leukocythemia
A seldom used term for leukaemia. ... Origin: Leukocyte + G. Haima, blood ... (05 Mar 2000) ...

leukocytic
Pertaining to or characterised by leukocytes. ... Synonym: leukocytal. ... (05 Mar 2000) ...

leukocytic pyrogens
Synonym for endogenous pyrogen ... Fever producing substance released by leucocytes (and Kuppfer cells in particular) that acts on the hypothalamic thermoregulatory centre. Now known to be interleukin-1. ... (18 Nov 1997) ...

leukocytic sarcoma
Synonym for leukaemia ... <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is clas …

leukocytoblast
A non-specific term for any immature cell from which a leukocyte develops, including lymphoblast, myeloblast, and the like. ... Origin: Leukocyte + G. Blastos, germ ... (05 Mar 2000) ...

leukocytoclasis
Karyorrhexis of leukocytes. ... Origin: Leuko-+ G. Kytos, cell, + klasia, a breaking ... (05 Mar 2000) ...

leukocytoclastic vasculitis
Cutaneous acute vasculitis characterised clinically by palpable purpura, especially of the legs, and histologically by exudation of the neutrophils and sometimes fibrin around dermal venules, with nuclear dust and extravasation of red cells; may be limited to the skin or involve other tissues as in Henoch-Schonlein purpura. ... See: cutaneous vascul …

leukocytogenesis
The formation and development of leukocytes. ... Origin: Leukocyte + G. Genesis, production ... (05 Mar 2000) ...

leukocytoid
Resembling a leukocyte. ... Origin: Leukocyte + G. Eidos, resemblance ... (05 Mar 2000) ...

leukocytolysin
Any substance (including lytic antibody) that causes dissolution of leukocytes. ... Synonym: leukolysin. ... (05 Mar 2000) ...

leukocytolysis
Dissolution or lysis of leukocytes. ... Synonym: leukolysis. ... Origin: Leukocyte + G. Lysis, dissolution ... (05 Mar 2000) ...

leukocytolytic
Pertaining to, causing, or manifesting leukocytolysis. ... Synonym: leukolytic. ... (05 Mar 2000) ...

leukocytoma
A fairly well circumscribed, nodular, dense accumulation of leukocytes. ... Origin: Leukocyte + G. -oma, tumour ... (05 Mar 2000) ...

leukocytometer
A standarised glass slide that is suitably ruled for counting the leukocytes in a measured volume of accurately diluted blood (or other specimens). ... Origin: Leukocyte + G. Metron, measure ... (05 Mar 2000) ...

leukocytopenia
Abnormal decrease in the number of leukocytes in the blood (white blood cells that help to combat infection). ... (16 Dec 1997) ...

leukocytoplania
Movement of leukocytes from the lumens of blood vessels, through serous membranes, or in the tissues. ... Origin: Leukocyte + G. Plane, a wandering ... (05 Mar 2000) ...

leukocytopoiesis
Synonym: leukopoiesis. ... Origin: Leukocyte + G. Poiesis, a making ... (05 Mar 2000) ...

leukocytosis
A term used to describe an abnormal elevation on the white blood cell count. Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. Elevated counts can be seen in cases of inflammation and infection. ... (27 Sep 1997) ...

leukocytosis of the newborn
An apparently 'physiologic' leukocytosis usually observed in newborn infants, in whom the white blood cell counts are usually greater than 10,000 per cu mm, and sometimes range to 45,000 per cu mm, resulting chiefly from increased numbers of neutrophils (especially single and bilobed forms). On the third or fourth day of life, the count generally d …

leukocytosis-promoting factor
A substance obtained by Menkin from inflammatory exudates; it stimulates leukocytosis. ... (05 Mar 2000) ...

leukocytotactic
Pertaining to, characterised by, or causing leukocytotaxia. ... Synonym: leukocytactic, leukotactic. ... (05 Mar 2000) ...

leukocytotaxia
1. The active ameboid movement of leukocytes, especially the neutrophilic granulocytes, either toward (positive leukocytotaxia) or away from (negative leukocytotaxia) certain microorganisms as well as various substances frequently formed in inflamed tissue. ... 2. The property of attracting or repelling leukocytes. ... Synonym: leukocytaxia, leukocyt …

leukocytotoxin
Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin. ... Synonym: leukotoxin. ... Origin: Leukocyte + G. Toxikon, poison ... (05 Mar 2000) ...

Leukocytozoon
Synonym for Leucocytozoon ... A genus of sporozoan parasites (family Plasmodiidae, suborder Haemosporina) that attack the immature red blood cells of birds and are capable of causing acute outbreaks of disease, particularly in turkeys and ducks; vectors are black flies, Simulium species, and the bloodsucking gnat Culicoides. ... Synonym: Leukocytozoo …

leukocytozoonosis
Synonym for leucocytozoonosis ... Infection of ducks, turkeys, chickens, pigeons, and doves with species of the protozoan genus Leucocytozoon. The disease is most acute and damaging in young turkeys and ducks, and is characterised by enlargement of the spleen and liver, anaemia, listlessness, weakness, and frequently death. ... Synonym: leukocytozoon …

leukocyturia
The presence of leukocytes in urine that is recently voided or collected by means of a catheter. ... Origin: Leukocyte + G. Ouron, urine ... (05 Mar 2000) ...

leukoderma
An absence of pigment, partial or total, in the skin. ... Synonym: achromoderma, hypomelanosis, leukopathia, leukopathy. ... Origin: Leuko-+ G. Derma, skin ... (05 Mar 2000) ...

leukoderma acquisitum centrifugum
Synonym for halo nevus ... A benign, sometimes multiple, melanocytic nevus in which involution occurs with a central brown mole surrounded by a uniformly depigmented zone or halo. ... Synonym: leukoderma acquisitum centrifugum, Sutton's disease, Sutton's nevus. ... (05 Mar 2000) ...

leukoderma colli
Synonym for syphilitic leukoderma ... A fading of the roseola of secondary syphilis, leaving reticulated depigmented and hyperpigmented areas located chiefly on the sides of the neck. ... Synonym: leukoderma colli, melanoleukoderma colli. ... (05 Mar 2000) ...

leukodermatous
Relating to or resembling leukoderma. ... (05 Mar 2000) ...

leukodontia
The condition of having white teeth. ... Origin: Leuko-+ G. Odous, tooth ... (05 Mar 2000) ...

leukodystrophia
Synonym: leukodystrophy. ... (05 Mar 2000) ...

leukodystrophia cerebri progressiva
Synonym for leukodystrophy ... <radiology> Type of dysmyelinating disease, hereditary, peripheral nervous system unaffected in some disorders Specific diseases: adrenoleukodystrophy, metachromatic leukodystrophy, spongy degeneration (Canavan), globoid cell (Krabbe) leukodystrophy, Alexander disease, Pelizaeus-Merzbacher disease, Cockayne syndr …

leukodystrophy
<radiology> Type of dysmyelinating disease, hereditary, peripheral nervous system unaffected in some disorders Specific diseases: adrenoleukodystrophy, metachromatic leukodystrophy, spongy degeneration (Canavan), globoid cell (Krabbe) leukodystrophy, Alexander disease, Pelizaeus-Merzbacher disease, Cockayne syndrome ... (12 Dec 1998) ...

leukodystrophy, globoid cell
An inherited metabolic disorder of the nervous system, particularly the white matter. It is characterised histologically by a paucity of myelin and oligodendroglia, severe astrocytic gliosis, and massive infiltration with unique multinucleated globoid cells which are enriched in galactosylceramide. The primary genetic defect is a deficiency of gala …

leukodystrophy, metachromatic
A sphingolipidosis where there is defective desulfation of galactosyl-3-sulfate ceramide due to a defective enzyme cerebroside sulfatase (arylsulfatase a). The result is an accumulation of sulfatide in neural and non-neural tissues which manifests as mental deterioration and severe disturbances of the central nervous system. ... (12 Dec 1998) ...

leukoedema
A bluish-white opalescence of the buccal mucosa which becomes the normal mucosal colour on stretching the tissue; most commonly observed in blacks and may be considered a normal anatomic variation. ... (05 Mar 2000) ...

leukoedema, oral
A disorder of the buccal mucosa resembling early leukoplakia, characterised by the presence of filmy opalescence of the mucosa in the early stages to a whitish gray cast with a coarsely wrinkled surface in the later stages, associated with intracellular oedema of the spinous or malpighian layer. ... (12 Dec 1998) ...

leukoencephalitis
Encephalitis restricted to the white matter. ... (05 Mar 2000) ...

leukoencephalopathy
White matter changes first described in children with leukaemia, associated with radiation and chemotherapy injury, often associated with methotrexate; pathologically characterised by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. ... Origin: Leuko-+ G. Enkephalos, brain, + pathos, suffering ... (05 Mar 2000) …

leukoerythroblastic anaemia
<haematology> Any anaemia condition which arises from a space occupying lesion in the bone marrow. The circulating blood contains immature cells of the granulocytic series and nucleated red blood cells, frequently in numbers that are disproportionately large in relation to the degree of anaemia. ... Origin: Gr. Haima = blood ... (27 Sep 1997)
leukoerythroblastosis
Any anaemic condition resulting from space-occupying lesions in the bone marrow; the circulating blood contains immature cells of the granulocytic series and nucleated red blood cells, frequently in numbers that are disproportionately large in relation to the degree of anaemia. ... Synonym: leukoerythroblastic anaemia, myelophthisic anaemia, myelopa …