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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

grandiose delusion
Synonym for delusion of grandeur ... A delusion in which one believes himself possessed of great wealth, intellect, importance and/or power, a common feature of schizophrenia. ... (27 Sep 1997) ...

grandiose delusions
A fixed false belief that involves themes of special powers or abilities (for example communicating with deceased relatives or extraterrestrial) ... (27 Sep 1997) ...

grandiose type of paranoid disorder
A delusion in which the person believes that he or she possesses some great but unrecognised talent or insight, or has made an important discovery, with subsequent efforts toward official or public recognition. ... (05 Mar 2000) ...

Grandry
M., 19th century French anatomist. ... See: Grandry's corpuscles. ... (05 Mar 2000) ...

Grandry's corpuscle
General sensory endings in the beak, mouth, and tongue of birds; similar to Merkel's corpuscle's. ... (05 Mar 2000) ...

Granger projection
G. View, reversed half-axial view; uncommonly used PA view of the skull. ... (05 Mar 2000) ...

Granger, Amedee
<person> U.S. Radiologist, 1879-1939. ... See: Granger's line. ... (05 Mar 2000) ...

Granger's line
On lateral skull radiographs, the line produced by the groove of the optic chiasm or sulcus prechiasmatis. ... (05 Mar 2000) ...

granins
Family of related acidic proteins (400-600 residues) found in many endocrine cell secretory vesicles. Secretogranin 1 = chromogranin B, secretogranin 2 = chromogranin C. ... (18 Nov 1997) ...

granisetron
<chemical> A serotonin receptor (5ht-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients. ... Pharmacological action: antiemetics, serotonin antagonists. ... Chemical name: 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-, endo- ... (12 Dec 1998) ...

Granit
Ragnar A., Finnish-Swedish neurophysiologist and Nobel laureate, 1900-1991 ... See: Granit's loop. ... (05 Mar 2000) ...

Granit's loop
Synonym for gamma loop ... The reflex arc consisting of small anterior horn cells and neuroma, their small fibres projecting to the intrafusal bundle producing its contraction, which initiates the afferent impulses that pass through the posterior root to the anterior horn cells, inducing a stretch reflex. ... Synonym: gamma motor neurons, gamma motor …

granite
<geology> A crystalline, granular rock, consisting of quartz, feldspar, and mica, and usually of a whitish, grayish, or flesh-red colour. It differs from gneiss in not having the mica in planes, and therefor in being destitute of a schistose structure. ... Varieties containing hornblende are common. See also the Note under Mica. Gneissoid gran …

granny knot
A double knot in which the free ends of the second loop are asymmetric and not in the same plane as the free ends of the first loop. ... (05 Mar 2000) ...

granola
A protein-rich cereal mixture composed of oats, wheat, wheat germ, sesame seeds, honey, brewers yeast and other ingredients. ... (27 Sep 1997) ...

granular
1. Composed of or resembling granules or granulations. ... 2. Particles with strong affinity for nuclear stains, seen in many bacterial species. ... (05 Mar 2000) ...

granular cast
A relatively dark, dense urinary cast of coarsely or finely particulate cellular debris and other proteinaceous material, frequently seen in chronic renal disease but also in the recovery phase of acute renal failure. ... See: waxy cast. ... (05 Mar 2000) ...

granular cell tumour
Unusual tumour affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead …

granular component of nucleolus
Area of nucleolus that appears granular in the electron microscope and contains 15nm diameter particles that are maturing ribosomes. In contrast to the pale staining and fibrillar areas. ... (18 Nov 1997) ...

granular conjunctivitis
Synonym for trachomatous conjunctivitis ... A chronic infection of the conjunctiva due to Chlamydia trachomatis, characterised by conjunctival follicles and subsequent cicatrization. ... See: trachoma. ... Synonym: granular conjunctivitis. ... (05 Mar 2000) ...

granular cortex
See: cerebral cortex. ... (05 Mar 2000) ...

granular degeneration
Synonym for cloudy swelling ... Swelling of cells due to injury to the membranes affecting ionic transfer; causes an accumulation of intracellular water. ... Synonym: albuminous swelling, granular degeneration, hydropic degeneration, parenchymatous degeneration. ... (05 Mar 2000) ...

granular endoplasmic reticulum
Endoplasmic reticulum in which ribosomal granules are applied to the cytoplasmic surface of the cisternae; involved in the synthesis and secretion of protein via membrane-bound vesicles to the extracellular space. ... Synonym: chromidial substance, ergastoplasm, rough-surfaced endoplasmic reticulum. ... (05 Mar 2000) ...

granular kidney
A kidney in which fairly uniform, diffusely and evenly situated foci of scarring of the interstitial tissue of the cortex (and sometimes scarring of glomeruli), and the associated slight degree of bulging of groups of dilated tubules, leads to the development of a minutely bosselated surface; such kidney's are seen in arteriolar nephrosclerosis or …

granular layer of cerebellar cortex
Synonym for granular layer of cerebellum ... The deepest of the three layers of the cortex; it contains large numbers of granule cells, the dendrites of which synapse with incoming mossy fibres in cerebellar glomeruli. Thin, unmyelinated axons of granule cells ascend perpendicularly into the molecular layer in which they bifurcate into fibres coursi …

granular layer of cerebellum
The deepest of the three layers of the cortex; it contains large numbers of granule cells, the dendrites of which synapse with incoming mossy fibres in cerebellar glomeruli. Thin, unmyelinated axons of granule cells ascend perpendicularly into the molecular layer in which they bifurcate into fibres coursing parallel to the long axis of the cerebell …

granular layer of epidermis
A layer of somewhat flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum and deeply to the stratum corneum. ... Synonym: stratum granulosum epidermidis. ... (05 Mar 2000) ...

granular layers of cerebral cortex
Layers 2 (outer) and 4 (inner) of the cortex cerebri. ... (05 Mar 2000) ...

granular layers of retina
Synonym for nuclear layers of retina ... The outer nuclear layer, layer 4, of the retina, neuroepithelial layer of retina, and the inner layer, layer 6, of the retina, ganglionic layer of retina. ... Synonym: granular layers of retina, stratum nucleare externum et internum retinae. ... (05 Mar 2000) ...

granular leukoblast
An obsolete term for promyelocyte. ... (05 Mar 2000) ...

granular leukocyte
Any one of the polymorphonuclear leukocyte's, especially a neutrophilic leukocyte. ... See: granulocyte, basophilic leukocyte, eosinophilic leukocyte. ... (05 Mar 2000) ...

granular lids
Synonym for trachoma ... <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. ... It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. ... The disease is as …

granular ophthalmia
Synonym for trachoma ... <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. ... It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. ... The disease is as …

granular pits
Pits on the inner surface of the skull, along the course of the superior sagittal sinus, in which are lodged the arachnoidal granulations. ... Synonym: foveolae granulares, pacchionian depressions. ... (05 Mar 2000) ...

granular pneumonocytes
Synonym for great alveolar cells ... Cuboidal cell's connected with the squamous pulmonary alveolar cell's and having in their cytoplasm lamellated bodies (cytosomes) that represent the source of the surfactant that coats the alveoli. ... Synonym: granular pneumonocytes, type II cells. ... (05 Mar 2000) ...

granular trachoma
Synonym for follicular trachoma ... <ophthalmology> The ordinary form of trachoma marked by the presence of granulations on the conjunctiva. ... Synonym: granular trachoma. ... (05 Mar 2000) ...

granular urethritis
Synonym for follicular urethritis ... <urology> Chronic urethritis with nodular lymphocytic infiltrations in the mucosa. ... Synonym: granular urethritis. ... (05 Mar 2000) ...

granular vaginitis
A condition of cattle manifested by the appearance of small, spherical, transparent nodules in the mucosa of the vagina of cows and of the penis of bulls; the mucosa is reddened and a mucopurulent exudate appears on the affected surfaces; it is a non specific hyperplastic response of the lymphatic tissue of these areas to an irritant or an antigen. …

granulate
Of a surface: granular. ... (09 Oct 1997) ...

granulated opium
Opium dried and reduced to a coarse powder; it contains 10 to 10.5% anhydrous morphine. ... (05 Mar 2000) ...

granulatio
Synonym: granulation. ... Origin: L. ... (05 Mar 2000) ...

granulation
1. The act or process of forming or crystallizing into grains; as, the granulation of powder and sugar. ... 2. The state of being granulated. ... 3. <medicine> One of the small, red, grainlike prominences which form on a raw surface (that of wounds or ulcers), and are the efficient agents in the process of healing. The act or process of the for …

granulation tissue
Highly vascularised tissue that replaces the initial fibrin clot in a wound. Vascularisation is by ingrowth of capillary endothelium from the surrounding vasculature. The tissue is also rich in fibroblasts (that will eventually produce the fibrous tissue) and leucocytes. ... (18 Nov 1997) ...

granulationes
Plural of granulatio. ... (05 Mar 2000) ...

granulationes arachnoideales
Synonym for arachnoid granulations ... Tufted prolongations of pia-arachnoid, composed of numerous arachnoid villi that penetrate dural venous sinuses and effect transfer of cerebrospinal fluid to the venous system. at advanced age these are more numerous and tend to calcify. ... Synonym: granulationes arachnoideales, arachnoidal granulations, pacchi …

granule
<pharmacology> A small quantity of a solid substance, smaller than a grain. ... Origin: L. Granulum ... (18 Nov 1997) ...

granule cell
Type of neuron found in the cerebellum. ... (18 Nov 1997) ...

granule cell of connective tissue
Synonym for mast cell ... <cell biology, immunology> Resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate. ... Release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to basophils and possibly derived from the same ste …

granule cells
Small nerve cell bodies in the external and internal granular layers of the cerebral cortex, small nerve cell bodies in the granular layer of the cerebellar cortex. ... (05 Mar 2000) ...

granulo-
Granular, granules. ... Origin: L. Granulum, a small grain. ... (05 Mar 2000) ...

granuloblast
Rarely used term for an immature haematopoietic cell capable of giving rise to granulocytes. ... Origin: Granulo-+ G. Blastos, germ ... (05 Mar 2000) ...

granuloblastosis
A leukaemic form of leukosis in the chicken characterised by an increase of immature, granular blood cells in the circulating blood and frequently infiltration of the parenchymatous organs. ... (05 Mar 2000) ...

granulocyte
<haematology> Leucocyte with conspicuous cytoplasmic granules. In humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils (using a Romanovsky type stain), some invertebrate blood cells are also referred to, n …

granulocytic leukaemia
<haematology, tumour> A form of leukaemia characterised by an uncontrolled proliferation of myelopoietic cells in the bone marrow and in extramedullary sites, and the presence of large numbers of immature and mature granulocytic forms in various tissues (and organs) and in the circulating blood. ... The total count may range from 1000 (aleukae …

granulocytic sarcoma
<tumour> A malignant tumour of immature myeloid cells, frequently subperiosteal, associated with or preceding granulocytic leukaemia. ... See: chloroma. ... Synonym: myeloid sarcoma. ... (05 Mar 2000) ...

granulocytic series
<haematology> The cells in the several stages of development in the bone marrow leading to the mature granulocyte of the circulation, e.g., myeloblasts, different stages of the myelocyte, granulocytes. ... (05 Mar 2000) ...

granulocytopenia
<haematology> A reduced number of white blood cells in the circulation. ... (18 Nov 1997) ...

granulocytopoiesis
Synonym for granulopoiesis ... <haematology> The production of granulocytes in the bone marrow. ... (18 Nov 1997) ...

granulocytopoietic
Synonym for granulopoietic ... Pertaining to granulopoiesis. ... Synonym: granulocytopoietic. ... (05 Mar 2000) ...

granulocytosis
<haematology> A condition characterised by more than the normal number of granulocytes in the circulating blood or in the tissues. ... (05 Mar 2000) ...

granuloma
<pathology> Chronic inflammatory lesion characterised by large numbers of cells of various types (macrophages, lymphocytes, fibroblasts, giant cells), some degrading and some repairing the tissues. ... (18 Nov 1997) ...

granuloma annulare
<dermatology> Benign granulomatous disease of unknown aetiology characterised by a ring of localised or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures. ... (12 Dec 1998) ...

granuloma endemicum
<dermatology, infectious disease> The lesion occurring in cutaneous leishmaniasis. ... (05 Mar 2000) ...

granuloma faciale
<dermatology> Persistent well-demarcated nodules that usually appear on the face and consist of a dense dermal infiltrate of eosinophils and neutrophils, separated from the epidermis and hair follicles, with fibrinoid vasculitis. ... (05 Mar 2000) ...

granuloma gangrenescens
Synonym for lethal midline granuloma ... Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. ... An obsolete term for polymorphic reticulosis. ... Synonym: …

granuloma gravidarum
A pyogenic granuloma developing on the gingiva during pregnancy; thought to be related to hormonally altered response of the oral mucous membranes to local irritants such as bacterial plaque on adjacent teeth. ... Synonym: pregnancy tumour. ... (05 Mar 2000) ...

granuloma inguinale
<disease, microbiology> A rare sexually transmitted disease that is caused by Calymmatobacterium granulomatis. ... This infection is more common in the tropical and subtropical areas such as India, Guyana and new Guinea. There are approximately 100 cases reported annually in the United States. Men are affected more often than women. It is thou …

granuloma inguinale tropicum
An elongated ulcer, with elevated papillary edges, sometimes occurring in the groin in persons in the tropics. ... Synonym: groin ulcer. ... (05 Mar 2000) ...

granuloma multiforme
A chronic granulomatous annular eruption of the skin on the upper body in older adults in central Africa; of unknown cause. ... (05 Mar 2000) ...

granuloma pudendi
Synonym for granuloma inguinale ... <disease, microbiology> A rare sexually transmitted disease that is caused by Calymmatobacterium granulomatis. ... This infection is more common in the tropical and subtropical areas such as India, Guyana and new Guinea. There are approximately 100 cases reported annually in the United States. Men are affecte …

granuloma telangiectaticum
Synonym for pyogenic granuloma ... Granuloma pyogenicum, an acquired small rounded mass of highly vascular granulation tissue, frequently with an ulcerated surface, projecting from the skin or mucosa; histologically, the mass resembles a capillary haemangioma. ... Synonym: granuloma telangiectaticum. ... (05 Mar 2000) ...

granuloma tropicum
Synonym for yaws ... <medicine> A disease, occurring in the Antilles and in Africa, characterised by yellowish or reddish tumours, of a contagious character, which, in shape and appearance, often resemble currants, strawberries, or raspberries. There are several varieties of this disease, variously known as framboesia, pian, verrugas, and crab …

granuloma venereum
Synonym for granuloma inguinale ... <disease, microbiology> A rare sexually transmitted disease that is caused by Calymmatobacterium granulomatis. ... This infection is more common in the tropical and subtropical areas such as India, Guyana and new Guinea. There are approximately 100 cases reported annually in the United States. Men are affecte …

granuloma, fish bowl
Localised nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called mycobacterium marinum. Fish bowl granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposure a …

granuloma, foreign-body
Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (giant cells, foreign-b0dy), usually surrounded by lymphocytes. ... (12 Dec 1998) ...

granuloma, laryngeal
A polypoid granulomatous projection into the lumen of the larynx. ... (12 Dec 1998) ...

granuloma, lethal midline
A non-neoplastic disease of unknown aetiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures. ... (12 Dec 1998) ...

granuloma, plasma cell
A slow-growing benign pseudotumour in which plasma cells greatly outnumber the inflammatory cells. ... (12 Dec 1998) ...

granuloma, plasma cell, orbital
A distinctive, chronic inflammatory reaction in the orbital tissues of the eye, of unknown aetiology, that may closely resemble a neoplasm and often becomes bilateral. Symptoms include exophthalmos and congestion of the lids with oedema. When limitation of ocular motility also occurs, it is sometimes called orbital myositis. ... (12 Dec 1998) ...

granuloma, plasma cell, pulmonary
A pseudotumour of the lung composed of inflammatory cells and showing complete maturity of fibroblastic components with a striking lack of mitosis. It is also called postinflammatory pseudotumour and pseudoneoplastic pneumonitis. (berardi, r.s. Et al. Inflammatory pseudotumours of the lung. Surg gynecol obstet 156:89-96, jan 83) ... (12 Dec 1998) …

granuloma, pyogenic
A usually solitary polypoid capillary haemangioma of the skin and gingival or oral mucosa, often associated with trauma or local irritation, representing a vasoproliferative inflammatory response. It presents as a small erythematous papule that enlarges and may become pedunculated and may become infected and ulcerate with accompanying purulent exud …

granuloma, respiratory tract
Granulomatous diseases affecting one or more sites in the respiratory tract. ... (12 Dec 1998) ...

granuloma, swimming pool
Localised nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called mycobacterium marinum. Swimming pool granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposu …

granulomatosis
Any condition characterised by multiple granulomas. ... (05 Mar 2000) ...

granulomatosis siderotica
A form in which firm, brown foci that contain iron pigment (Gamna bodies) are present in an enlarged spleen. ... (05 Mar 2000) ...

granulomatous
Having the characteristics of a granuloma. ... (05 Mar 2000) ...

granulomatous arteritis
Synonym for temporal arteritis ... giant cell arteritis ...

granulomatous colitis
Changes, identical to those of regional enteritis, involving the colon. ... (05 Mar 2000) ...

granulomatous disease
Synonym for chronic granulomatous disease ... <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase. ... Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the …

granulomatous disease, chronic
A recessive x-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. ... (12 Dec 1998) ...

granulomatous encephalomyelitis
An encephalomyelitis in which granulomas occur. ... (05 Mar 2000) ...

granulomatous endophthalmitis
A diffuse, chronic inflammation of intraocular tissues. ... (05 Mar 2000) ...

granulomatous enteritis
Crohn's disease, a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease usually affects persons in their teens or early twenties. It tends to be a chronic, …

granulomatous ileitis
Crohn's disease involving the ileum (the lowest portion of the small intestine). ... (12 Dec 1998) ...

granulomatous inflammation
A form of proliferative inflammation ... See: granuloma. ... (05 Mar 2000) ...

granulomatous mastitis
A rare granulomatous inflammation of lobular breast tissue, with multinucleated giant cells; sarcoidosis is excluded by the frequent presence of neutrophils and absence of involvement of other tissues. ... (05 Mar 2000) ...

granulomatous nocardiosis
A form of nocardiosis characterised by emaciation, abdominal distention, and replacement of lymphoid tissue in lymph nodes and spleen by granulomatous tissue. ... (05 Mar 2000) ...

granulomatous rosacea
Papular lesions in rosacea, characterised microscopically by perifollicular granulomas with central necrosis and scattered giant cells. Lupus miliaris disseminatus faciei is probably a form of granulomatous rosacea. ... Synonym: rosacea-like tuberculid, tuberculoid rosacea. ... (05 Mar 2000) ...

granulomere
The central part of a blood platelet. ... Synonym: chromomere. ... Origin: Granulo-+ G. Meros, a part ... (05 Mar 2000) ...

granulopenia
Synonym for granulocytopenia ... <haematology> A reduced number of white blood cells in the circulation. ... (18 Nov 1997) ...