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mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


phenylalanine oxidase
<enzyme> Forms phenylpyruvate in the presence of air; consider also phenylalanine dehydrogenase (nad) which requires nad ... Registry number: EC 1.4.3.- ... Synonym: phenylalanine desaminase, l-phenylalanine oxidase, phenylalanine dehydrogenase ... (26 Jun 1999) ...

phenylalanine-tRNA ligase
<enzyme> An enzyme that activates phenylalanine with its specific transfer RNA. ... Chemical name: Phenylalanine:tRNA(Phe) ligase (AMP-forming) ... Registry number: EC 6.1.1.20 ... (12 Dec 1998) ...

phenylalanyl chain
Synonym for B chain ... A polypeptide component of insulin containing 30 amino acyl residues, beginning with a phenylalanyl residue (NH2-terminus); insulin is formed by the linkage of a B chain to an A chain by two disulfide bonds; the amino-acid composition of the B chain is a function of species. ... Synonym: phenylalanyl chain. ... (05 Mar 2000) …

phenylalanyl-arginyl-aminopeptidase
<enzyme> An aspecific kininase ... Registry number: EC 3.4.11.- ... Synonym: phe-arg-aminopeptidase, phenylalanyl-arginylaminopeptidase ... (26 Jun 1999) ...

phenylbutazone
<chemical> A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate …

phenylcarbinol
Synonym for benzyl alcohol ... <chemical> A colourless liquid with a sharp burning taste and slight odour. It is used as a local anaesthetic and to reduce pain associated with lidocaine injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring. ... Pharmacological action: ana …

phenyldichloroarsine
C6H5A5Cl2;A toxic liquid that has been used as a blister and vomiting agent by certain military and police organizations; it was first used in a limited manner in World War I. ... (05 Mar 2000) ...

phenylephrine
<chemical> An alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent. ... Pharmacological action: adrenergic alpha-agonists, cardiotonic agent, mydriatics, nasal decongestants, sympathomimetic, vasoconstrictor agents. ... Chemical name: Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)- ... (12 Dec 199 …

phenylephrine hydrochloride
<drug> An alpha 1 adrenergic agonist. ... (15 Oct 1997) ...

phenylethyl alcohol
<chemical> An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery. ... Pharmacological action: anti-infective agents, local, disinfectants, preservatives, pharmaceutical. ... Chemical name: Benzeneethanol ... (12 Dec 1998) ...

phenylethylamine oxidase
<enzyme> Contains a quinone cofactor, possibly topa quinone; isolated from arthrobacter globiformis; genbank u03517 ... Registry number: EC 1.4.3.- ... (26 Jun 1999) ...

phenylethylbarbituric acid
Synonym for phenobarbital ... <chemical> A barbiturate used as a sedative and an anticonvulsant. It was used as an anti-anxiety agent but has been supplanted by benzodiazepines for that purpose. It may also be useful in the treatment of neonatal hyperbilirubinaemia and in the symptomatic treatment of opiate withdrawal in mothers and infants.
phenylethylmalonamide
<chemical> 2-ethyl-2-phenylmalonamide. A metabolite of primidone. ... Chemical name: Propanediamide, 2-ethyl-2-phenyl- ... (12 Dec 1998) ...

phenylethylmalonylurea
Synonym for phenobarbital ... <chemical> A barbiturate used as a sedative and an anticonvulsant. It was used as an anti-anxiety agent but has been supplanted by benzodiazepines for that purpose. It may also be useful in the treatment of neonatal hyperbilirubinaemia and in the symptomatic treatment of opiate withdrawal in mothers and infants.
phenylglycolic acid
Synonym for mandelic acid ... C6H5CHOHCOOH;a urinary antibacterial agent (both bactericidal and bacteriostatic). ... Synonym: hydroxytoluic acid, phenylglycolic acid. ... Origin: Ger. Mandel, almond ... (05 Mar 2000) ...

phenylglyoxal
<chemical> Alpha-oxo-benzeneacetaldehyde. A reagent that is highly selective for the modification of arginyl residues. It is used to selectively inhibit various enzymes and acts as an energy transfer inhibitor in photophosphorylation. ... Pharmacological action: enzyme inhibitors, indicators and reagents. ... Chemical name: Benzeneacetaldehyde, …

phenylhydrazine haemolysis
An in vitro test for G6PD deficiency; haemolysis resulting from in vitro addition of phenylhydrazine to blood with red cells which are deficient in glucose-6-phosphate dehydrogenase (G6PD), with the appearance of Heinz-Ehrlich bodies. ... (05 Mar 2000) ...

phenylhydrazines
Diazo derivatives of aniline, used as a reagent for sugars, ketones, and aldehydes. ... (12 Dec 1998) ...

phenylindanedione
Synonym for phenindione ... <chemical> An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects. ... Pharmacological action: anticoagulant. ... Chemical name: 1H-Indene-1,3(2H)-dione, 2-phenyl- ... (12 Dec 1998) ...

phenylisopropyladenosine
<chemical> N-isopropyl-n-phenyl-adenosine. Antilipaemic agent. Synonym: th 162. ... Chemical name: Adenosine, N-(1-methylethyl)-N-phenyl- ... (12 Dec 1998) ...

phenylisothiocyanate
C6H5-N==C==S, a reagent that condenses with the free N-terminal amino group of a peptide chain to form a phenylthiohydantoin in the Edman method of identifying N-terminal amino acids. ... Synonym: Edman's reagent. ... Acronym: PITC ... (05 Mar 2000) ...

phenylketonuria
<disease> Congenital absence of phenylalanine hydroxylase (an enzyme that converts phenylalanine into tyrosine). Phenylalanine accumulates in blood and seriously impairs early neuronal development. The defect can be controlled by diet and is not serious if treated in this way. ... Incidence: highest in Caucasians. ... Acronym: PKU ... Origin: Gr …

phenylketonuria, maternal
Phenylketonuria in a pregnant woman. The maternal disease puts the foetus at great risk of mental retardation and other congenital diseases. ... (12 Dec 1998) ...

phenyllactic acid
C6H5CH2CHOH==COOH;a product of phenylalanine catabolism, appearing prominently in the urine in individuals with phenylketonuria. ... (05 Mar 2000) ...

phenylmercuric acetate
<chemical> A phenyl mercury compound used mainly as a fungicide. Has also been used as a herbicide, slimicide, and bacteriocide. ... Pharmacological action: fungicides, industrial, pharmaceutic aid. ... Chemical name: Mercury, (acetato-O)phenyl- ... (12 Dec 1998) ...

phenylmercuric nitrate
Basic phenylmercuric nitrate;a mixture of phenylmercuric nitrate and phenylmercuric hydroxide; an antiseptic used for the prophylactic disinfection of the intact skin or of minor wounds. ... (05 Mar 2000) ...

phenylmercury compounds
<chemical> Organic mercury compounds in which the mercury is attached to a phenyl group. Often used as fungicides and seed treatment agents. ... Pharmacological action: fungicides, industrial. ... (12 Dec 1998) ...

phenylmethylsulfonyl fluoride
<chemical> Alpha-toluenesulfonyl fluoride. An enzyme inhibitor that inactivates irc-50 arvin, subtilisin, and the fatty acid synthetase complex. ... Pharmacological action: enzyme inhibitors, protease inhibitors. ... Chemical name: Benzenemethanesulfonyl fluoride ... (12 Dec 1998) ...

phenylpropanolamine
<chemical> A sympathomimetic that acts mainly by causing release of norepinephrine but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant. ... Pharmacological action: adrenergic alpha-agonists, adrenergic agents, appetite depressants, nasal decongestants …

phenylpyruvate oligophrenia
Synonym for phenylketonuria ... <disease> Congenital absence of phenylalanine hydroxylase (an enzyme that converts phenylalanine into tyrosine). Phenylalanine accumulates in blood and seriously impairs early neuronal development. The defect can be controlled by diet and is not serious if treated in this way. ... Incidence: highest in Caucasians …

phenylpyruvate oxidase
<enzyme> Phenylpyruvate is converted to o-hydroxyphenyl-acetic acid ... Registry number: EC 1.- ... (26 Jun 1999) ...

phenylpyruvic acid
C6H5-CH2COCOOH;the transaminated product of the action of phenylalanine aminotransferase; elevated in the urine in individuals with phenylketonuria. ... (05 Mar 2000) ...

phenylpyruvic acids
A group of compounds that are derivatives of phenylpyruvic acid which has the general formula c6h5ch2cocooh, and is a metabolite of phenylalanine. ... (12 Dec 1998) ...

phenylpyruvic amentia
Amentia accompanied by the appearance of phenylpyruvate in the urine. ... (05 Mar 2000) ...

phenylthiazolylthiourea
<chemical> 1-phenyl-3-(2-thiazolyl)-2-thiourea. A dopamine-beta-hydroxylase inhibitor. Synonym: u-14,624. ... Chemical name: Thiourea, N-phenyl-N'-2-thiazolyl- ... (12 Dec 1998) ...

phenylthiocarbamide
Synonym for phenylthiourea ... <chemical> Chemical name: Thiourea, phenyl- ... (12 Dec 1998) ...

phenylthiocarbamoyl
See: phenylthiocarbamoyl peptide. ... (05 Mar 2000) ...

phenylthiocarbamoyl peptide
The peptide formed by combination of phenylisothiocyanate and an alpha-amino group of a peptide. ... See: phenylthiohydantoin. ... (05 Mar 2000) ...

phenylthiocarbamoyl protein
Formed by the reaction of phenylisothiocyanate with a terminal alpha-amino group of a peptide or protein ... See: phenylisothiocyanate, phenylthiohydantoin. ... Synonym: PhNCS protein, PTC protein. ... (05 Mar 2000) ...

phenylthiohydantoin
<chemical> 3-phenyl-2-thiohydantoin. Thiohydantoin benzene derivative. ... Chemical name: 4-Imidazolidinone, 3-phenyl-2-thioxo- ... (12 Dec 1998) ...

phenylthiourea
<chemical> Chemical name: Thiourea, phenyl- ... (12 Dec 1998) ...

phenyltoloxamine
N,N-dimethyl-2-(alpha-phenyl-o-tolyloxy)-ethylamine;an antihistaminic. ... (05 Mar 2000) ...

phenyltrimethylammonium
A highly selective stimulant of the motor endplates of skeletal muscle. ... Acronym: PTMA ... (05 Mar 2000) ...

phenyramidol hydrochloride
Alpha-(2-Pyridylaminomethyl)benzyl alcohol hydrochloride;an analgesic and a muscle relaxant. ... (05 Mar 2000) ...

phenytoin
<drug> A medication commonly used to treat seizure disorders and epilepsy. ... (15 Oct 1997) ...

pheo-
1. Prefix denoting the same substituents on a phorbin or phorbide (porphyrin) residue as are present in chlorophyll, excluding any ester residues and Mg. ... 2. Combining form meaning gray, dark-coloured. ... Origin: G. Phaios, dusky ... (05 Mar 2000) ...

pheochrome
Synonym: chromaffin. ... 2. Staining darkly with chromic salts. ... Origin: G. Phaios, dusky, + chroma, colour ... (05 Mar 2000) ...

pheochrome cell
Former term for enteroendocrine cell. ... Synonym: pheochromocyte. ... (05 Mar 2000) ...

pheochromoblast
A primitive chromaffin cell which, with sympathetoblasts, enters into the formation of the adrenal gland. ... Origin: G. Phaios, dusky, + chroma, colour, + blastos, germ ... (05 Mar 2000) ...

pheochromoblastoma
<tumour> Obsolete term for pheochromocytoma. ... (05 Mar 2000) ...

pheochromocyte
A chromaffin cell of a sympathetic paraganglion, medulla of an adrenal gland, or of a pheochromocytoma. ... Synonym: pheochrome cell. ... Origin: pheochrome + G. Kytos, cell ... (05 Mar 2000) ...

pheochromocytoma
<oncology, tumour> A tumour of the adrenal gland which produces catecholamines (noradrenaline and adrenaline). Although the tumour is usually benign it produces hypertension, pounding headaches, tachycardia, palpitations, apprehension, facial flushing, nausea and vomiting. ... A diagnosis can be made using a urine test which measures the quant …

pheomelanin
A type of melanin found in red hair; it contains sulfur and is alkali-soluble; elevated levels are found in the rufous type of oculocutaneous albinism. ... Compare: eumelanin. ... Origin: G. Phaios, dusky, + melos (melan-), black ... (05 Mar 2000) ...

pheomelanogenesis
The formation of pheomelanin by living cells. ... (05 Mar 2000) ...

pheomelanosome
A spherical melanosome of pheomelanin in red hair. ... (05 Mar 2000) ...

pheophytins
Chlorophylls from which the magnesium has been removed by treatment with weak acid. ... (12 Dec 1998) ...

pheresis
A procedure in which blood is removed from a donor, separated, and a portion retained, with the remainder returned to the donor. ... See: leukapheresis, plateletpheresis, plasmapheresis. ... Origin: G. Aphairesis, a withdrawal ... (05 Mar 2000) ...

pheromone
<endocrinology> A volatile hormone or behaviour modifying agent. Normally used to describe sex attractants for example bombesin for the moth Bombyx, but includes volatile aggression stimulating agents (e.g. Isoamyl acetate in honey bees). ... (18 Nov 1997) ...

pheromones
Chemical substances which, when secreted by an individual into the environment, cause specific reactions in other individuals, usually of the same species. The substances relate only to multicellular organisms. This includes kairomones. Allomones are repellent pheromones. ... (12 Dec 1998) ...

PhG
1. <abbreviation> Pharmacopoeia Germanica; German Pharmacopoeia. ... 2. <abbreviation> Graduate in Pharmacy, a degree no longer offered in the U.S. ... (05 Mar 2000) ...

phi
1. The 21st letter of the Greek alphabet. ... 2. (&Phi;) Symbol for phenyl; potential energy; magnetic flux. ... 3. (&phi;) Symbol for plane angle; volume fraction; quantum yield; the dihedral angle of rotation about the N-Ca bond associated with a peptide bond. ... (05 Mar 2000) ...

phi phenomenon
An illusion of movement, which occurs by means of successive visual impressions at intervals of 1/15 to 1/20 sec; when an occluder is passed from one eye to the other while a small distant light is observed, the light seems to move with the occluder in exophoria, but in an opposite direction in oesophoria. ... (05 Mar 2000) ...

phi X 174
<molecular biology> Bacteriophage of E. Coli with a single stranded DNA genome and an icosahedral shell. This was the first DNA phage to be fully sequenced: the genome consists of 10 genes, some of which are overlapping genes. ... (18 Nov 1997) ...

phialide
In fungi, a conidiogenous cell in which the meristematic end remains unchanged as successive conidia are extruded out to form chains. ... Origin: G. Phiale, a broad, flat vessel ... (05 Mar 2000) ...

phialoconidium
A conidium produced by a phialide. ... (05 Mar 2000) ...

Phialophora
A genus of fungi of which at least two species, Phialophora verrucosa and Phialophora dermatitidis, cause chromoblastomycosis. ... Origin: G. Phiale, a broad, flat vessel, + phoreo, to carry ... (05 Mar 2000) ...

Philadelphia chromosome
<genetics, oncology> Characteristic chromosomal abnormality in which a portion of chromosome 22 is translocated to chromosome 9. This abnormality is found in nearly all cases of chronic myeloid leukaemia and some cases of acute lymphoblastic leukaemia. ... (30 Sep 1997) ...

Philadelphia cocktail
Synonym for Rivers' cocktail ... An intravenous slow injection of from 1000 to 2000 ml of 10% dextrose in isotonic saline to which thiamine hydrochloride and 25 units of insulin are added; used in acute alcoholism. ... Synonym: Philadelphia cocktail. ... (05 Mar 2000) ...

philanthropic hospital
Synonym for voluntary hospital ... A hospital supported in part by voluntary contributions and under the control of a local, usually self-appointed, board of managers; a non-profit hospital. ... Synonym: philanthropic hospital. ... (05 Mar 2000) ...

philately
Study of stamps or postal markings. It usually refers to the design and commemorative aspects of the stamp. ... (12 Dec 1998) ...

philiater
Rarely used term for one interested in the study of medicine. ... Origin: G. Philos, fond, + iatreia, practice of medicine ... (05 Mar 2000) ...

Philip's glands
Enlarged deep gland's just above the clavicle, found in children with pulmonary tuberculosis and occasionally in others. ... (05 Mar 2000) ...

Philippe
Claudien, French pathologist, 1866-1903. ... See: Philippe's triangle. ... (05 Mar 2000) ...

Philippe's triangle
See: semilunar fasciculus. ... (05 Mar 2000) ...

Philippine haemorrhagic fever
Severe arbovirus infection with haemorrhagic manifestations, considerable mortality, probably due to mosquito borne dengue virus; seen in tropical and subtropical urban areas of southeast Asia, South Pacific, Australia, Central and South America, and the Caribbean islands. ... (05 Mar 2000) ...

philistine
1. A native or an inhabitant of ancient Philistia, a coast region of southern Palestine. ... 2. A bailiff. ... 3. A person deficient in liberal culture and refinement; one without appreciation of the nobler aspirations and sentiments of humanity; one whose scope is limited to selfish and material interests. ... Origin: L. Philistinus, Heb. Phlishthi, …

Phillips
Charles, French urologist, 1809-1871. ... See: Phillips' catheter. ... (05 Mar 2000) ...

Phillips' catheter
A catheter with a filiform guide for the urethra. ... (05 Mar 2000) ...

Phillipson's reflex
A contraction of the extensors of the knee when the extensors of the opposite knee are inhibited. ... (05 Mar 2000) ...

philo-
See: -phil. ... Origin: G. Philos, fond, loving; phileo, to love ... (05 Mar 2000) ...

philology
1. Criticism; grammatical learning. ... 2. <study> The study of language, especially in a philosophical manner and as a science; the investigation of the laws of human speech, the relation of different tongues to one another, and historical development of languages; linguistic science. ... Philology comprehends a knowledge of the etymology, or …

philology, classical
The study of ancient greek and roman literature, including grammar, etymology, criticism, literary history, and language and linguistic history. ... (12 Dec 1998) ...

philology, oriental
The study of literature written in languages of asia and the far east, including grammar, etymology, criticism, literary history, and language and linguistic history. ... (12 Dec 1998) ...

philology, romance
The study of literature written in the romance languages (french, spanish, italian, and others descended from latin), including grammar, etymology, criticism, literary history, and language and linguistic history. ... (12 Dec 1998) ...

philomimesia
Rarely used term for a morbid impulse to imitate or mimic. ... Origin: philo-+ G. Mimesis, imitation ... (05 Mar 2000) ...

Philopia casei
A species that may cause temporary intestinal myiasis. ... Synonym: cheese maggot. ... (05 Mar 2000) ...

philoprogenitive
1. Procreative, producing offspring. ... 2. In psychiatry, manifesting an erotic or abnormal love for children. ... Origin: philo-+ L. Progenies, offspring, progeny ... (05 Mar 2000) ...

philosopher
1. One who philosophizes; one versed in, or devoted to, philosophy. 'Then certain philosophers of the Epicureans, and of the Stoics, encountered him.' (Acts xvii. 18) ... 2. One who reduces the principles of philosophy to practice in the conduct of life; one who lives according to the rules of practical wisdom; one who meets or regards all vicissitu …

philosopher's stone
A stone sought by the alchemists of the Middle Ages which was supposedly able to transmute base metals into gold, to make precious stone's, and to cure all ills, and thus confer longevity; it was also believed to be a universal solvent. ... (05 Mar 2000) ...

philosophy
Origin: OE. Philosophie, F. Philosophie, L. Philosophia, from Gr. See Philosopher. ... 1. Literally, the love of, including the search after, wisdom; in actual usage, the knowledge of phenomena as explained by, and resolved into, causes and reasons, powers and laws. ... When applied to any particular department of knowledge, philosophy denotes the ge …

philtrum
The area from below the nose to the upper lip. Normally the philtrum is grooved. In foetal alcohol syndrome, the philtrum is flat. ... (12 Dec 1998) ...

phimotic
Pertaining to phimosis. ... (05 Mar 2000) ...

phleb-
See: phlebo-. ... (05 Mar 2000) ...

phlebalgia
Pain originating in a vein. ... Origin: phlebo-+ G. Algos, pain ... (05 Mar 2000) ...

phlebectasia
Vasodilation of the veins. ... Synonym: venectasia. ... Origin: phlebo-+ G. Ektasis, a stretching ... (05 Mar 2000) ...

phlebectomy
<procedure> Excision of a segment of a vein, performed sometimes for the cure of varicose veins. ... See: strip. ... Synonym: venectomy. ... Origin: phlebo-+ G. Ektome, excision ... (05 Mar 2000) ...

phlebeurysm
Pathologic dilation (varix) of a vein. ... Origin: phlebo-+ G. Eurys, wide ... (05 Mar 2000) ...

phlebitic
Relating to phlebitis. ... (05 Mar 2000) ...

phlebitis
<pathology> Inflammation of a vein. The condition is marked by infiltration of the coats of the vein and the formation of a thrombus. The disease is attended by oedema, stiffness and pain in the affected part and in the septic variety by pyaemic symptoms. ... Origin: Gr. Phlebos = vein. ... (11 Jun 1998) ...

phlebo-
Means vein. ... (12 Dec 1998) ...