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mondofacto - Online Medical Dictionary
Category: Health and Medicine > Medical Dictionary
Date & country: 26/01/2008, UK
Words: 116197


instrumental amusia
Loss of ability to play a musical instrument. ... (05 Mar 2000) ...

instrumental conditioning
Conditioning in which the response is a prerequisite to achieving some goal; often used as a synonym for operant conditioning, but some psychologists make distinctions in the usages of these two terms. ... (05 Mar 2000) ...

instrumentarium
A collection of instruments and other equipment for an operation or for a medical procedure. ... (05 Mar 2000) ...

instrumentation
1. The use of instruments. ... 2. In dentistry, the application of armamentarium in a restorative procedure. ... (05 Mar 2000) ...

insudate
Fluid swelling within an arterial wall (ordinarily serous), differing from an exudate in that it does not come to lie extramurally. ... Origin: L. In, in, + sudo, pp. -atus, to sweat ... (05 Mar 2000) ...

insufficiency
The condition of being insufficient or inadequate to the performance of the allotted duty. ... Origin: L. Insufficientia, from sufficiens = sufficient ... (18 Nov 1997) ...

insufficient
1. Not sufficient; not enough; inadequate to any need, use, or purpose; as, the provisions are insufficient in quantity, and defective in quality. 'Insufficient for His praise.' ... 2. Wanting in strength, power, ability, capacity, or skill; incompetent; incapable; unfit; as, a person insufficient to discharge the duties of an office. ... Synonym: In …

insufflate
May involve injection of carbon dioxide into the peritoneum to achieve pneumoperitoneum during laparoscopy and laparoscopic surgery. ... Origin: L. In-sufflo, to blow on or into ... (05 Mar 2000) ...

insufflation anaesthesia
Maintenance of inhalation anaesthesia by delivery of anaesthetic gases or vapors directly to the airway of a spontaneously breathing patient. ... (05 Mar 2000) ...

insufflator
An instrument used in insufflation. ... (05 Mar 2000) ...

insula
1. An oval region of the cerebral cortex overlying the extreme capsule, lateral to the lenticular nucleus, buried in the depth of the fissura lateralis cerebri (sylvian fissure). ... Synonym: insular area, insular cortex, island of Reil. ... Synonym: island. ... 3. Any circumscribed body or patch on the skin. ... Origin: L. Island ... (05 Mar 2000) ...

insular
Relating to any insula, especially the island of Reil. ... (05 Mar 2000) ...

insular area
Synonym for insula ... 1. An oval region of the cerebral cortex overlying the extreme capsule, lateral to the lenticular nucleus, buried in the depth of the fissura lateralis cerebri (sylvian fissure). ... Synonym: insular area, insular cortex, island of Reil. ... Synonym: island. ... 3. Any circumscribed body or patch on the skin. ... Origin: L. Island …

insular arteries
Branches from the insular part of the middle cerebral artery distributed to the cortex of the insula. ... Synonym: arteriae insulares. ... (05 Mar 2000) ...

insular cortex
Synonym for insula ... 1. An oval region of the cerebral cortex overlying the extreme capsule, lateral to the lenticular nucleus, buried in the depth of the fissura lateralis cerebri (sylvian fissure). ... Synonym: insular area, insular cortex, island of Reil. ... Synonym: island. ... 3. Any circumscribed body or patch on the skin. ... Origin: L. Island …

insular gyri
The short gyri of insula and long gyrus of insula. ... Synonym: gyri insulae. ... (05 Mar 2000) ...

insular hypothesis
An obsolete theory of the origin of diabetes mellitus from destruction or loss of function of the islets of Langerhans in the pancreas. ... (05 Mar 2000) ...

insular part
Synonym for pars insularis ... insular part ...

insular sclerosis
Synonym for multiple sclerosis ... <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still un …

insular veins
Synonym for venae insulares ... Veins draining the cortex of the insula, tributaries to the deep middle cerebral vein. ... Synonym: insular veins. ... (05 Mar 2000) ...

insulate
1. To make an island of. ... 2. To place in a detached situation, or in a state having no communication with surrounding objects; to isolate; to separate. ... 3. <physics> To prevent the transfer o electricity or heat to or from (bodies) by the interposition of nonconductors. ... <physics> Insulating stool, a stool with legs of glass or so …

insulated
1. Standing by itself; not being contiguous to other bodies; separated; unconnected; isolated; as, an insulated house or column. 'The special and insulated situation of the Jews.' (De Quincey) ... 2. <physics> Separated from other bodies by means of nonconductors of heat or electricity. ... 3. <astronomy> Situated at so great a distance a …

insulin
<drug, growth factor, hormone> A polypeptide hormone (bovine insulin, 5780D) found in both vertebrates and invertebrates. ... Secreted by the _ cells of the pancreas in response to high blood sugar levels, it induces hypoglycaemia. Defective secretion of insulin is the cause of diabetes mellitus. Insulin is also a mitogen, has sequence homolog …

insulin activating factor
<chemical> Activates insulin gene transcription in pancreatic beta cells. ... Synonym: insaf ... (05 Dec 1998) ...

insulin allergy
When a person's body has an allergic or bad reaction to taking insulin made from pork or beef or from bacteria, or because the insulin is not exactly the same as human insulin or because it has impurities. The allergy can be of two forms. Sometimes an area of skin becomes red and itchy around the place where the insulin is injected. This is called …

insulin antagonist
Something that opposes or fights the action of insulin. Insulin lowers the level of glucose (sugar) in the blood, whereas glucagon raises it, therefore, glucagon is an antagonist of insulin. ... (09 Oct 1997) ...

insulin binding
When insulin attaches itself to something else. This can occur in two ways. First, when a cell needs energy, insulin can bind with the outer part of the cell. The cell then can bring glucose (sugar) inside and use it for energy. With the help of insulin, the cell can do its work very well and very quickly. But sometimes the body acts against itself …

insulin c-peptide
<investigation> A blood test which measures the amount of C-peptide in the blood. C-peptide is a byproduct of normal insulin production by the beta cells in the pancreas. ... Normal values are 0.5 to 3.0 ng/ml. Normal levels indicate that the body is still producing its own insulin. Low levels indicate that the pancreas is producing little or …

insulin coma treatment
Rarely used treatment of major mental illness by means of hypoglycaemic coma induced by insulin. ... (05 Mar 2000) ...

insulin dependent diabetes
A form of diabetes that requires the daily injection of the hormone insulin to maintain normal body chemistry. Avoidance of insulin in these patients will result in a severe metabolic derangement known as diabetic ketoacidosis. ... (27 Sep 1997) ...

insulin hypoglycaemia test
A test to determine the completeness of vagotomy for peptic ulcer; after the surgical procedure is performed, insulin is administered to cause hypoglycaemia; if vagotomy is complete, the acid output from the stomach following administration of insulin is less than that before insulin administration; if the reverse if true, incomplete vagotomy is li …

insulin infusion systems
Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic …

insulin injection
A preparation that may contain 20, 40, 80, 100, or 500 USP insulin units per ml, although the trend is toward standardizing all insulin preparations at 100 units per ml; it is administered subcutaneously, occasionally intravenously, and has a rapid onset of action, has a brief duration (5 to 7 hours), and is compatible for mixing with long-acting i …

insulin like growth factor
<growth factor> Insulin like growth factors I and II are polypeptides with considerable sequence similarity to insulin. ... They are capable of eliciting the same biological responses, including mitogenesis in cell culture. On the cell surface, there are two types of insulin like growth factor receptor, one of which closely resembles the insul …

insulin lipoatrophy
Synonym for insulin lipodystrophy ... Dystrophic atrophy of subcutaneous tissues in diabetics at the site of frequent injections of insulin. ... Synonym: insulin lipoatrophy. ... (05 Mar 2000) ...

insulin lipodystrophy
Dystrophic atrophy of subcutaneous tissues in diabetics at the site of frequent injections of insulin. ... Synonym: insulin lipoatrophy. ... (05 Mar 2000) ...

insulin pump
A device that delivers a continuous supply of insulin into the body. The insulin flows from the pump through a plastic tube that is connected to a needle inserted into the body and taped in place. Insulin is delivered at two rates: a low, steady rate (called the basal rate) for continuous day-long coverage, and extra boosts of insulin (called bolus …

insulin reaction
A sudden uncontrolled decline in the blood sugar due to effects of insulin. ... (27 Sep 1997) ...

insulin receptor
Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood. When the cell and insulin bind together, the cell can take glucose (sugar) from the blood and use it for energy. ... (09 Oct 1997) ...

insulin resistance
Many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin. This may happen because the person is overweight and has too many fat cells, which do not respond well to insulin. Also, as people age, their body cells lose some of the ability to respond to insulin. Insulin resistance i …

insulin shock
A severe condition that occurs when the level of blood glucose (sugar) drops quickly. The signs are shaking, sweating, dizziness, double vision, convulsions, and collapse. Insulin shock may occur when an insulin reaction is not treated quickly enough. ... See: hypoglycaemia. ... (09 Oct 1997) ...

insulin shock treatment
Formerly used treatment for serious mental disorders in which the patient was given insulin to induce a seizure; supplanted by electroshock therapy. ... (05 Mar 2000) ...

insulin unit
The activity contained in 1/22 mg of the international standard of zinc-insulin crystals. ... (05 Mar 2000) ...

insulin zinc suspension
A sterile buffered suspension with zinc chloride, containing 40 or 80 units per ml; the solid phase of the suspension consists of a mixture of 7 parts of crystalline insulin and 3 parts of amorphous insulin. ... Synonym: lente insulin. ... (05 Mar 2000) ...

insulin-antagonizing factor
Synonym for glycotropic factor ... A principle in extracts of the anterior lobe of the hypophysis that raises the blood sugar and antagonises the action of insulin; purified pituitary growth hormone produces an identical effect. ... Synonym: insulin-antagonizing factor. ... (05 Mar 2000) ...

insulin-dependent diabetes mellitus
A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed. The body is then not able to use the glucose (blood sugar) for energy. IDDM usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, a …

insulin-like activity
A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin. ... (05 Mar 2000) ...

insulin-like growth factor I
<chemical> A well-characterised basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be mainly active in adults in contrast to insulin-like growth factor …

insulin-like growth factor II
<chemical> A well-characterised neutral peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be a major foetal growth factor in contrast to insulin-like growth f …

insulin-like growth factors
Peptides whose formation is stimulated by growth hormone. These peptides bring about peripheral tissue effects of that hormone and have high (about 70%) homology to human insulin. ... Synonym: somatomedins. ... (05 Mar 2000) ...

insulin-stimulating peptide
<chemical> 71-amino acid containing peptide; corresponds to residues 115-143 and 144-184 of bovine serum albumin with the exception of a tyrosine insertion between residues 155 and 156; consists of two chains with mw 5000 and 3400 for each chain ... Synonym: h-isp, insulin-stimulating protein ... (05 Dec 1998) ...

insulin, isophane
<chemical> An intermediate-acting insulin with an approximate time of onset of 2 hours and duration of action of 24 hours, consisting of bovine or pork insulin reacted with zinc chloride and protamine to form a protein complex with a ratio of free and bound insulin, providing action intermediate between regular insulin and protamine zinc insu …

insulin, lente
<chemical> Sterile suspension, in a buffered water medium, of insulin modified by the addition of zinc chloride in a manner such that the solid phase of the suspension conisists of a mixture of crystals and amorphous material in a ratio of approximately 7:3. ... Pharmacological action: hypoglycaemic agents. ... Chemical name: Insulin zinc ... (1 …

insulin, protamine zinc
<chemical> A long-acting insulin with an approximate time of onset of 7 hours and duration of action 36 hours, consisting of bovine or pork insulin reacted with zinc chloride and protamine to form a protein complex from which insulin is slowly released. ... Pharmacological action: hypoglycaemic agents. ... Chemical name: Insulin protamine zinc< …

insulinaemia
Literally, insulin in the circulating blood; usually connotes abnormally large concentrations of insulin in the circulating blood. ... Origin: insulin + G. Haima, blood ... (05 Mar 2000) ...

insulinogenesis
Production of insulin. ... Origin: insulin + G. Genesis, production ... (05 Mar 2000) ...

insulinogenic
Insulogenic ... Relating to insulinogenesis. ... (05 Mar 2000) ...

insulinoma
<oncology, tumour> An insulin producing tumour in the pancreas. ... (27 Sep 1997) ...

insulinopenic diabetes
Any form of diabetes mellitus resulting from inadequate secretion of insulin. ... (05 Mar 2000) ...

insulitis
Inflammation of the islands of Langerhans, with lymphocytic infiltration which may result from viral infection and be the initial lesion of insulin-dependent diabetes mellitus. ... Origin: L. Insula, island, + -itis, inflammation ... (05 Mar 2000) ...

insuloma
<tumour> Synonym: insulinoma. ... Origin: L. Insula, island, + -oma, tumour ... (05 Mar 2000) ...

insult
Injury or trauma, attack. ... Origin: L. Insultus = attack ... (18 Nov 1997) ...

insulysin
<enzyme> An enzyme the catalyses the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents edta and 1,10-phenanthroline, and by thiol-blocking reagents such as n-ethylmaleimide, but not phosphoramidon. (eur j biochem 1994;223:1-5) ... Registry number: EC 3.4.24.56 ... (12 Dec 1998) ...

insurance
Coverage by contract whereby one part indemnifies or guarantees another against loss by a specified contingency. ... (12 Dec 1998) ...

insurance benefits
Payments or services provided under stated circumstances under the terms of an insurance policy. In prepayment programs, benefits are the services the programs will provide at defined locations and to the extent needed. ... (12 Dec 1998) ...

insurance carriers
Organizations which assume the financial responsibility for the risks of policyholders. ... (12 Dec 1998) ...

insurance claim reporting
The design, completion, and filing of forms with the insurer. ... (12 Dec 1998) ...

insurance claim review
Review of claims by insurance companies to determine liability and amount of payment for various services. The review may also include determination of eligibility of the claimant or beneficiary or of the provider of the benefit; determination that the benefit is covered or not payable under another policy; or determination that the service was nec …

insurance coverage
Generally refers to the amount of protection available and the kind of loss which would be paid for under an insurance contract with an insurer. (slee & slee, health care terms, 2d ed) ... (12 Dec 1998) ...

insurance pools
An organization of insurers or reinsurers through which particular types of risk are shared or pooled. The risk of high loss by a particular insurance company is transferred to the group as a whole (the insurance pool) with premiums, losses, and expenses shared in agreed amounts. ... (12 Dec 1998) ...

insurance selection bias
Adverse of favourable selection bias exhibited by insurers or enrollees resulting in disproportionate enrollment of certain groups of people. ... (12 Dec 1998) ...

insurance, accident
Insurance providing coverage for physical injury suffered as a result of unavoidable circumstances. ... (12 Dec 1998) ...

insurance, dental
Insurance providing coverage for dental care. ... (12 Dec 1998) ...

insurance, disability
Insurance designed to compensate persons who lose wages because of illness or injury; insurance providing periodic payments that partially replace lost wages, salary, or other income when the insured is unable to work because of illness, injury, or disease. Individual and group disability insurance are two types of such coverage. ... (12 Dec 1998)
insurance, health
Insurance providing coverage of medical, surgical, or hospital care in general or for which there is no specific heading. ... (12 Dec 1998) ...

insurance, health, reimbursement
Payment by a third-party payer in a sum equal to the amount expended by a health care provider or facility for health services rendered to an insured or program beneficiary. ... (12 Dec 1998) ...

insurance, hospitalization
Health insurance providing benefits to cover or partly cover hospital expenses. ... (12 Dec 1998) ...

insurance, liability
Insurance against loss resulting from liability for injury or damage to the persons or property of others. ... (12 Dec 1998) ...

insurance, life
Insurance providing for payment of a stipulated sum to a designated beneficiary upon death of the insured. ... (12 Dec 1998) ...

insurance, long-term care
Health insurance to provide full or partial coverage for long-term home care services or for long-term nursing care provided in a residential facility such as a nursing home. ... (12 Dec 1998) ...

insurance, major medical
Insurance providing a broad range of medical services and supplies, when prescribed by a physician, whether or not the patient is hospitalised. It frequently is an extension of a basic policy and benefits will not begin until the basic policy is exhausted. ... (12 Dec 1998) ...

insurance, medigap
A supplemental health insurance policy sold by private insurance companies and designed to pay for health care costs and services that are not paid for either by medicare alone or by a combination of medicare and existing private health insurance benefits. ... (12 Dec 1998) ...

insurance, nursing services
Insurance providing benefits for the costs of care provided by nurses, especially nurse practitioners and nurse clinicians. ... (12 Dec 1998) ...

insurance, pharmaceutical services
Insurance providing for payment of services rendered by the pharmacist. Services include the preparation and distribution of medical products. ... (12 Dec 1998) ...

insurance, physician services
Insurance providing benefits for the costs of care by a physician which can be comprehensive or limited to surgical expenses or for care provided only in the hospital. It is frequently called 'regular medical expense' or 'surgical expense'. ... (12 Dec 1998) ...

insurance, psychiatric
Insurance providing benefits to cover part or all of the psychiatric care. ... (12 Dec 1998) ...

insurance, surgical
A specific type of health insurance which provides surgeons' fees for specified amounts according to the type of surgery listed in the policy. ... (12 Dec 1998) ...

insusceptibility
Synonym: immunity. ... Origin: L. Suscipio, pp. -ceptus, to take upon one, fr. Sub, under, + capio, to take ... (05 Mar 2000) ...

int 1
<oncogene> Oncogene from mouse mammary carcinoma that encodes a secreted protein. Related to Drosophila gene wingless. ... (18 Nov 1997) ...

int 2
<oncogene> Oncogene from mouse mammary carcinoma that encodes a member of fibroblast growth factor receptor family. ... (18 Nov 1997) ...

intact
Of a living body or its parts: physically and functionally complete: having no relevant component removed or destroyed. ... (18 Nov 1997) ...

integral
1. Lacking nothing of completeness; complete; perfect; uninjured; whole; entire. 'A local motion keepeth bodies integral.' (Bacon) ... 2. Essential to completeness; constituent, as a part; pertaining to, or serving to form, an integer; integrant. 'Ceasing to do evil, and doing good, are the two great integral parts that complete this duty.' (South)< …

integral dose
The total energy absorbed by the body, the product of the mass of tissue irradiated and the absorbed dose; unit, the gram rad. ... (05 Mar 2000) ...

integral membrane protein
<protein> A protein that is firmly anchored in a membrane (unlike a peripheral membrane protein). most is known about the integral proteins of the plasma membrane, where important examples include hormone receptors, ion channels and transport proteins. An integral protein need not cross the entire membrane, those that do are referred to as tr …

integral proteins
Proteins that cannot be easily separated from a biomembrane. ... Synonym: intrinsic proteins. ... (05 Mar 2000) ...

integrant
Making part of a whole; necessary to constitute an entire thing; integral. 'All these are integrant parts of the republic.' (Burke) Integrant parts, or particles, of bodies, those smaller particles into which a body may be reduced without loss of its original constitution, as by mechanical division. ... Origin: L. Integrans, -antis, p. Pr. Of integr …

integrase
<enzyme> The HIV enzyme that inserts HIV's genes into a cells normal DNA. ... Integrase operates after reverse transcriptase has created a DNA version of the RNA form of HIV genes present in virus particles. Drugs that block the action of integrase are under development. ... (18 Nov 1997) ...

integrase inhibitors
Compounds which inhibit or antagonise biosynthesis or actions of integrase. ... (12 Dec 1998) ...

integrase protein
<enzyme> An enzyme of the bacteriophage lambda (_) that catalyses the integration of phage DNA into the host DNA. ... (18 Nov 1997) ...

integrate
1. To form into one whole; to make entire; to complete; to renew; to restore; to perfect. 'That conquest rounded and integrated the glorious empire.' 'Two distinct substances, the soul and body, go to compound and integrate the man.' (South) ... 2. To indicate the whole of; to give the sum or total of; as, an integrating anemometer, one that indicat …