Copy of `mondofacto - Online Medical Dictionary`

The wordlist doesn't exist anymore, or, the website doesn't exist anymore. On this page you can find a copy of the original information. The information may have been taken offline because it is outdated.

mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

deoxyadenylic acid
Deoxyadenosine monophosphate, a hydrolysis product of DNA, differing from adenylic acid in containing deoxyribose in place of ribose. ... Synonym: adenine deoxyribonucleotide. ... (05 Mar 2000) ...

deoxybarbiturate
A barbiturate compound lacking the oxygen atom at the #2 position in the ring; example of a deoxybarbiturate is the antiepileptic drug, primidone. ... See: barbiturate. ... (05 Mar 2000) ...

deoxycholate
<biochemistry> A bile salt. The sodium salt is used as a detergent to make membrane proteins water soluble. ... (18 Nov 1997) ...

deoxycholic acid
<chemical> (3 alpha,5 beta,12 alpha)-3,12-dihydroxy-5-cholan-24-oic acid. A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilise fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent. ... Pharmacological …

deoxycholoyl-CoA synthetase
<enzyme> Catalyses the synthesis of deoxycholoyl-CoA from deoxycholic acid in rat liver ... Registry number: EC 6.2.1.- ... Synonym: deoxycholic acid CoA ligase, deoxycholate CoA ligase, deoxycholoyl-coenzyme a synthetase ... (26 Jun 1999) ...

deoxycoformycin
A purine analog which acts as an antimetabolite; potent inhibitor of adenosine deaminase. Used as an antineoplastic agent. ... See: pentostatin. ... (05 Mar 2000) ...

deoxycorticosterone
11-Deoxycorticosterone; 21-hydroxypregn-4-ene-3,20-dione;an adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, that rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity. ... Synonym: 21-hydroxyprogesterone, cortexone, deoxycortone, de …

deoxycortone
Synonym for deoxycorticosterone ... 11-Deoxycorticosterone; 21-hydroxypregn-4-ene-3,20-dione;an adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, that rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity. ... Synonym: 21-hydroxyproges …

deoxycytidine
<chemical> Chemical name: Cytidine, 2'-deoxy- ... (12 Dec 1998) ...

deoxycytidine kinase
<enzyme> An enzyme that catalyses reversibly the phosphorylation of deoxycytidine with the formation of a nucleoside diphosphate and deoxycytidine monophosphate. Cytosine arabinoside can also act as an acceptor. All natural nucleoside triphosphates, except deoxycytidine triphosphate, can act as donors. The enzyme is induced by some viruses, p …

deoxycytidine monophosphate
<chemical> Deoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. ... Chemical name: 5'-Cytidylic acid, 2'-deoxy- ... (12 Dec 1998) ...

deoxycytidylate methylase
<enzyme> From lactobacillus casei; mutation of asparagine 229 to aspartate in thymidylate synthetase converts the mutant to an excellent catalyst for methylation of dcmp ... Registry number: EC 2.1.1.- ... Synonym: dcmp methylase ... (26 Jun 1999) ...

deoxycytidylic acid
Deoxycytidine monophosphate, a hydrolysis product of DNA. ... (05 Mar 2000) ...

deoxycytosine nucleotides
Cytosine nucleotides which contain deoxyribose as the sugar moiety. ... (12 Dec 1998) ...

deoxyepinephrine
<chemical> 4-[2-(methylamino)ethyl]pyrocatechol. Sympathomimetic, vasoconstrictor agent. Synonym: epinine. ... Chemical name: 1,2-Benzenediol, 4-(2-(methylamino)ethyl)- ... (12 Dec 1998) ...

deoxyglucose
<chemical> 2-deoxy-d-arabino-hexose. An antimetabolite of glucose with antiviral activity. ... Pharmacological action: antimetabolites, antiviral agents. ... Chemical name: D-arabino-Hexose, 2-deoxy- ... (12 Dec 1998) ...

deoxyguanine nucleotides
Guanine nucleotides which contain deoxyribose as the sugar moiety. ... (12 Dec 1998) ...

deoxyguanosine
<chemical> A nucleoside consisting of the base guanine and the sugar deoxyribose. ... Chemical name: Guanosine, 2'-deoxy- ... (12 Dec 1998) ...

deoxyguanosine kinase
<enzyme> ATP serves as phosphate donor; various deoxyribonucleoside phosphates and ribonucleoside phosphates are formed ... Registry number: EC 2.7.1.113 ... Synonym: AMP deoxyguanosine phosphotransferase ... (26 Jun 1999) ...

deoxyguanylic acid
Deoxyguanosine monophosphate, a hydrolysis product of DNA. ... Synonym: guanine deoxyribonucleotide. ... (05 Mar 2000) ...

deoxyhaemoglobin
<protein> Haemoglobin without bound oxygen. ... (18 Nov 1997) ...

deoxyhexose
A 6-carbon deoxy-sugar in which one OH is replaced by H. ... (05 Mar 2000) ...

deoxyhypusine hydroxylase
<enzyme> Catalyses formation of hypusine from deoxyhypusine; does not require alpha-ketoglutarate, iron or ascorbic acid ... Registry number: EC 1.14.99.29 ... (26 Jun 1999) ...

deoxyhypusine synthase
<enzyme> Catalyses the transfer of the 4-aminobutyl moiety from spermidine to the epsilon amino group of a specific lysine residue ... Registry number: EC 1.5.1.- ... Synonym: spermidine dehydrogenase (nad, l-deoxyhypusyl-forming) ... (26 Jun 1999) ...

deoxyinosine 3' endonuclease
<enzyme> Cleaves the second phosphodiester bond 3' to deoxyinosine; active on oligonucleotides with deoxyinosine pairs, deoxyinosine-containing single-stranded DNA, and on DNA containing abasic sites (ap) or urea ... Registry number: EC 3.1.- ... Synonym: deoxyinosine 3'-endonuclease ... (26 Jun 1999) ...

deoxynojirimycin
Antibiotic produced by Bacillus spp, inhibits _ glucosidases and thus interferes with the glycosylation of cell surface glycoproteins. ... (18 Nov 1997) ...

deoxynucleoside
<biochemistry> A molecule composed of a nitrogenous base attached to the five-carbon sugar deoxyribose. ... (09 Oct 1997) ...

deoxynucleoside-phosphate kinase
<enzyme> Deoxynucleotide kinase was en to nucleoside monophosphate kinases 1982-93; deoxynucleoside monophosphate kinase was en to nucleoside monophosphate kinases 1983-93 ... Registry number: EC 2.7.4.13 ... Synonym: deoxynucleotide kinase, deoxynucleoside monophosphate kinase, deoxynucleoside-monophosphate kinase, deoxyribonucleoside 5'-monop …

deoxynucleotidase
<enzyme> Acts on 5'-deoxynucleotides ... Registry number: EC 3.1.3.- ... (26 Jun 1999) ...

deoxynucleotide
Synonym for deoxyribonucleoside ... A nucleoside component of DNA containing 2-deoxy-d-ribose; the condensation product of deoxy-d-ribose with purines or pyrimidines. ... (05 Mar 2000) ...

deoxypentose
<chemistry> A 5-carbon deoxy-sugar in which one OH is replaced by H. ... (05 Mar 2000) ...

deoxypyrimidine 5'-nucleotidase
<enzyme> From human erythrocytes; broad specificity; most active with pyrimidine deoxyribonucleotides ... Registry number: EC 3.1.3.- ... (26 Jun 1999) ...

deoxyriboaldolase
Synonym for deoxyribosephosphate aldolase ... <enzyme> An enzyme catalyzing cleavage of 2-deoxy-d-ribose 5-phosphate to d-glyceraldehyde 3-phosphate and acetaldehyde. ... Synonym: deoxyriboaldolase. ... (05 Mar 2000) ...

deoxyribodipyrimidine photo-lyase
<enzyme> An enzyme in yeast that is activated by light, whereupon it can reverse a previous photochemical reaction by cleaving the cyclobutane ring of the thymine dimer. ... It catalyses the reactivation by light of UV-irradiated DNA and cleaves two carbon-carbon bonds in pyrimidine dimers in DNA. ... Synonym: dipyrimidine photolyase, photoreac …

deoxyribomononucleotidase
<enzyme> Acholeplasma and mycoplasma enzyme; converts deoxyribonucleotides to the corresponding deoxyribonucleosides; acts on damp, dimp and dgmp ... Registry number: EC 3.1.3.- ... (26 Jun 1999) ...

deoxyribonuclease
<enzyme> An endonuclease with preference for DNA. Pancreatic DNAse I yields di and oligo nucleotide 5_ phosphates, pancreatic DNAse II yields 3_ phosphates. In chromatin, the sensitivity of DNA to digestion by DNAse I depends on its state of organisation, transcriptionally active genes being much more sensitive than inactive genes. ... Acronym …

deoxyribonuclease bamhi
<enzyme> One of the type II site-specific deoxyribonucleases (ec 3.1.21.4). It recognises and cleaves the sequence g/gatcc at the slash. Bamhi is from bacillus amyloliquefaciens n. Numerous isoschizomers have been identified. ... Registry number: EC 3.1.21.- ... (12 Dec 1998) ...

deoxyribonuclease ecori
<enzyme> One of the type II site-specific deoxyribonucleases (ec 3.1.21.4). It recognises and cleaves the sequence g/aattc at the slash. Ecori is from e coliry13. Several isoschizomers have been identified. ... Registry number: EC 3.1.21.- ... (12 Dec 1998) ...

deoxyribonuclease hindiii
<enzyme> One of the type II site-specific deoxyribonucleases (ec 3.1.21.4). It recognises and cleaves the sequence a/agctt at the slash. Hindiii is from haemophilus influenzae r(d). Numerous isoschizomers have been identified. ... Registry number: EC 3.1.21.- ... (12 Dec 1998) ...

deoxyribonuclease hpaii
<enzyme> One of the type II site-specific deoxyribonucleases (ec 3.1.21.4). It recognises and cleaves the sequences c/cgg and ggc/c at the slash. Hpaii is from haemophilus parainfluenzae. Several isoschizomers have been identified. ... Registry number: EC 3.1.21.- ... (12 Dec 1998) ...

deoxyribonuclease I
<enzyme> An enzyme capable of hydrolyzing highly polymerised DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyses endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA. ... Registry number: EC 3.1.21.1< …

deoxyribonuclease II
An endonuclease that cleaves both strands of native DNA (as well as single-stranded DNA) to produce a mixture of oligodeoxynucleotides, each ending in a 3'-phosphate. ... Synonym: acid deoxyribonuclease. ... (05 Mar 2000) ...

deoxyribonuclease S1
Synonym for endonuclease S1 Aspergillus ... <enzyme> An enzyme cleaving RNA or DNA to 5'-ended mono-or oligonucleotides; prefers single stranded polynucleic acids. ... Synonym: deoxyribonuclease S1. ... (05 Mar 2000) ...

deoxyribonucleases
<enzyme> Enzymes which catalyze the hydrolases of ester bonds within DNA. ... Registry number: EC 3.1.- ... (12 Dec 1998) ...

deoxyribonucleic acid
Synonym for DNA ... <cell biology, molecular biology> Deoxyribonucleic acid. ... The molecule that encodes genetic information in the nucleus of cells. It determines the structure, function and behaviour of the cell. ... DNA is a double-stranded molecule held together by weak bonds between base pairs of nucleotides. The four nucleotides in DNA c …

deoxyribonucleoprotein
The complex of DNA and protein in which DNA is usually found upon cell disruption and isolation. ... (05 Mar 2000) ...

deoxyribonucleoproteins
Proteins conjugated with deoxyribonucleic acids (DNA) or specific DNA. ... (12 Dec 1998) ...

deoxyribonucleoside
A nucleoside component of DNA containing 2-deoxy-d-ribose; the condensation product of deoxy-d-ribose with purines or pyrimidines. ... (05 Mar 2000) ...

deoxyribonucleosides
Nucleosides having a purine or pyrimidine base bonded to deoxyribose. ... (12 Dec 1998) ...

deoxyribonucleotide
<biochemistry> A molecule composed of a nitrogenous base attached to the five-carbon sugar deoxyribose, which also has a phosphate group attached to it. ... (09 Oct 1997) ...

deoxyribonucleotides
Nucleotides consisting of a purine or a pyrimidine base bonded to deoxyribose, which in turn is bound to a phosphate group. ... (12 Dec 1998) ...

deoxyribopyrimidine triphosphatase
<enzyme> Degrades dutp, dctp and dttp to corresponding monophosphates ... Registry number: EC 3.6.1.- ... Synonym: deoxypyrimidine triphosphatase, dpytase ... (26 Jun 1999) ...

deoxyribose
2 deoxy D ribose, the sugar that when linked by 3_ 5_ phosphodiester bonds forms the backbone of DNA. ... (18 Nov 1997) ...

deoxyribose phosphate
See: deoxyribonucleotide. ... (05 Mar 2000) ...

deoxyribosephosphate aldolase
<enzyme> An enzyme catalyzing cleavage of 2-deoxy-d-ribose 5-phosphate to d-glyceraldehyde 3-phosphate and acetaldehyde. ... Synonym: deoxyriboaldolase. ... (05 Mar 2000) ...

deoxyriboside
Deoxyribose combined via its 1-O atom with a radical derived from an alcohol; not to be confused with deoxyribosyl compounds such as deoxyribonucleosides. ... Compare: deoxyribosyl. ... (05 Mar 2000) ...

deoxyribosyl
The radical formed from deoxyribose by removal of the OH from the C1 carbon; e.g., deoxyadenosine. ... Compare: deoxyriboside. ... (05 Mar 2000) ...

deoxyribosyltransferases
Enzymes that catalyze the transfer of 2-deoxy-d-ribose from deoxyribosides to free bases. ... (05 Mar 2000) ...

deoxyribotide
Misnomer for deoxyribonucleotide or deoxynucleotide derived, by analogy with nucleoside-nucleotide, from incorrect usage of deoxyriboside. ... (05 Mar 2000) ...

deoxythymidine
Synonym for thymidine ... <biochemistry> Term that is always used in practice for the nucleoside thymine deoxyriboside, not the riboside which naming of the other nucleosides might lead one to expect. ... (18 Nov 1997) ...

deoxythymidylic acid
A component of DNA; originally and properly called thymidylic acid, but use of deoxy-is less ambiguous, as ribothymidylic acid is now known to exist. ... Synonym: thymine deoxyribonucleotide. ... (05 Mar 2000) ...

deoxyuracil nucleotides
Uracil nucleotides which contain deoxyribose as the sugar moiety. ... (12 Dec 1998) ...

deoxyuridine
<chemical> 2'-deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anaemias due to vitamin b12 and folate deficiencies. ... Pharmacological action: antimetabolites. ... Chemical name: Uridine, 2'-deoxy- ... (12 Dec 1998) ...

deoxyuridine 1'-hydroxylase
<enzyme> Forms deoxyribolactone (or ribolactone)+uracil+succinate; requires fe++, alpha-ketoglutarate and o2 ... Registry number: EC 1.14.11.- ... Synonym: uridine 1'-hydroxylase, deoxyuridine, 2-oxoglutarate dioxygenase, deoxyuridine (uridine) 1'-hydroxylase ... (26 Jun 1999) ...

deoxyvirus
Synonym for DNA virus ... <molecular biology, virology> A virus in which the nucleic acid is double or single stranded DNA (rather than RNA). Major groups of double stranded DNA viruses are papovaviruses, adenoviruses, herpes viruses, large bacteriophages and poxviruses: of single stranded, parvoviruses and coliphages _X174 and M13. ... (18 Nov …

deoxyxylulose-5-phosphate synthase
<enzyme> Catalyses thiamin diphosphate-dependent acyloin condensation between pyruvate and glyceraldehyde ... Registry number: EC 2.2.1.- ... Synonym: dxp synthase ... (26 Jun 1999) ...

deozonise
To deprive of ozone. ... (05 Mar 2000) ...

depactin
<protein> Actin depolymerising protein (17.6 kD) originally isolated from echinoderm eggs. Apparently unlike other actin binding proteins. ... (18 Nov 1997) ...

depart
1. To part; to divide; to separate. Division; separation, as of compound substances into their ingredients. ... 2. A going away; departure; hence, death. To pass away; to perish ... 3. To go forth or away; to quit, leave, or separate, as from a place or a person; to withdraw; opposed to arrive; often with from before the place, person, or thing left, …

department
1. Act of departing; departure. 'Sudden departments from one extreme to another.' (Wotton) ... 2. A part, portion, or subdivision. ... 3. A distinct course of life, action, study, or the like; appointed sphere or walk; province. 'Superior to Pope in Pope's own peculiar department of literature.' (Macaulay) ... 4. Subdivision of business or official du …

Department of Energy
Department within the executive branch of the U.S. Government (at the cabinet level) which has managed and overseen federally-sponsored energy research. It was formed in 1977 from the Energy Research and Development Administration, and the Atomic Enegy Commission. ... Acronym: DOE ... (10 Nov 1998) ...

departure
1. Division; separation; putting away. 'No other remedy . . . But absolute departure.' (Milton) ... 2. Separation or removal from a place; the act or process of departing or going away. 'Departure from this happy place.' (Milton) ... 3. Removal from the present life; death; decease. 'The time of my departure is at hand.' (2 Tim. Iv. 6) 'His timely de …

dependence
The quality or condition of relying upon, being influenced by, or being subservient to a person or object reflecting a particular need. ... Origin: L. Dependeo, to hang from ... (05 Mar 2000) ...

dependency
<psychology> The tendency of an individual or individuals to rely on others for advice, guidance, or support. ... (12 Dec 1998) ...

dependent
Exhibiting dependence or dependency. ... (18 Nov 1997) ...

dependent beat
Synonym for forced beat ... <cardiology, physiology> An extrasystole supposedly precipitated in some way by the preceding normal beat to which it is coupled, an extrasystole caused by artificial stimulation of the heart. ... Synonym: dependent beat. ... (05 Mar 2000) ...

dependent drainage
Drainage from the lowest part and into a receptacle at a level lower than the structure being drained. ... Synonym: downward drainage. ... (05 Mar 2000) ...

dependent oedema
A clinically detectable increase in extracellular fluid volume localised in a dependent area, as of a limb, characterised by swelling or pitting. ... (05 Mar 2000) ...

dependent personality
A personality in which a person passively allows others to assume responsibility for making decisions affecting him/her, characterised by a lack of self-confidence and an inability to function independently. ... (05 Mar 2000) ...

dependent personality disorder
An individual who fears separation and engaging othhers to assume responsibility ... (27 Sep 1997) ...

dependent variable
In experiments, a variable that is influenced by or dependent upon changes in the independent variable; e.g., the amount of a written passage retained (dependent variable) as a function of the different numbers of minutes (independent variable) allowed to study the passage. ... (05 Mar 2000) ...

dependovirus
<virology> A genus of viruses in the family Parvoviridae which are all defective viruses (unable to replicate by themselves) and depend on the co-infection of their host cell by other, nondefective viruses to help them replicate. ... (09 Oct 1997) ...

depersonalisation
<psychiatry> Alteration in the perception of the self so that the usual sense of one's own reality is lost, manifested in a sense of unreality or self estrangement, in changes of body image or in a feeling that one does not control his own actions and speech, seen in depersonalisation disorder, schizophrenic disorders and schizotypal personal …

depersonalization
An alteration in the perception of the self so that the usual sense of one's own reality is lost, manifested in a sense of unreality or self-estrangement, in changes of body image, or in a feeling that one does not control his own actions and speech. ... (12 Dec 1998) ...

depersonalization disorder
Synonym for schizophrenia ... <psychiatry> A mental disorder or heterogeneous group of disorders (the schizophrenias or schizophrenic disorders) comprising most major psychotic disorders and characterised by disturbances in form and content of thought (loosening of associations, delusions and hallucinations) mood (blunted, flattened or inappro …

depersonalization syndrome
Synonym for depersonalization ... An alteration in the perception of the self so that the usual sense of one's own reality is lost, manifested in a sense of unreality or self-estrangement, in changes of body image, or in a feeling that one does not control his own actions and speech. ... (12 Dec 1998) ...

dephasing
In the magnetic resonance, following alignment by a radiofrequency pulse, the gradual loss of orientation of the magnetic atomic nuclei due to random molecular energy transfer or relaxation. ... (05 Mar 2000) ...

dephosphorylation
<biochemistry> Removal of a phosphate group. ... (18 Nov 1997) ...

depigmentation
<dermatology> The removal or loss of pigment, especially melanin. ... (18 Nov 1997) ...

depilate
To remove hair by any means. ... Compare: epilate. ... Origin: L. De-pilo, pp. -atus, to deprive of hair, fr. De-neg. + pilo, to grow hair ... (05 Mar 2000) ...

depilation
Synonym for epilation ... The act or result of removing hair. ... Synonym: depilation. ... (05 Mar 2000) ...

depilatory
Synonym: epilatory. ... 2. An agent that causes the falling out of hair. ... Synonym: epilatory. ... Chemical depilatory, a topically applied depilatory substance. ... (05 Mar 2000) ...

deplete
1. <medicine> To empty or unload, as the vessels of human system, by bloodletting or by medicine. ... 2. To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc. ... Origin: From L. Deplere to empty out; de- + plere to fill. Forined like replete, complete. See Fil …

depletion
1. The act or process of emptying, removal of a fluid, as the blood. ... 2. Exhausted state which results from excessive loss of blood. ... Origin: L. Deplere = to empty ... (18 Nov 1997) ...

depletion method
<molecular biology, technique> A lab technique to isolate mRNA molecules from a specific gene by hybridising all of the mRNA molecules from a cell to a specific segment of DNA. The one mRNA molecule type which actually sticks is the one looked for. ... (09 Oct 1997) ...

depletion response
Subnormal metabolic response to trauma in a person whose physiologic processes are already depressed by disease. ... (05 Mar 2000) ...

deploy
To open out; to unfold; to spread out (a body of troops) in such a way that they shall display a wider front and less depth; the reverse of ploy; as, to deploy a column of troops into line of battle. ... Origin: F. Deployer; pref. De = des (L. Dis) + ployer, equiv. To plier to fold, fr. L. Plicare. See Ply, and cf. Display. ... Source: Websters Dicti …

depolarisation
The process or act of neutralising polarity, depriving of polarity, or the result of such action; reduction to an unpolarised condition. ... <physiology> The reversal of the resting potential in excitable cell membranes when stimulated i.e., the tendency of the cell membrane potential to become positive with respect to the potential outside th …

depolarise
1. <optics> To deprive of polarity; to reduce to an unpolarised condition. ... This word has been inaccurately applied in optics to describe the effect of a polarising medium, as a crystalline plate, in causing the reappearance of a ray, in consequence of a change in its plane of polarisation, which previously to the change was intercepted by …

depolarising block
<physiology> Skeletal muscle paralysis associated with loss of polarity of the motor endplate, as occurs following administration of succinylcholine. ... (05 Mar 2000) ...