Copy of `mondofacto - Online Medical Dictionary`

The wordlist doesn't exist anymore, or, the website doesn't exist anymore. On this page you can find a copy of the original information. The information may have been taken offline because it is outdated.

mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

thrombelastography
Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis. ... (12 Dec 1998) ...

thrombi
Plural of thrombus. ... (05 Mar 2000) ...

thrombin
<enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. ... Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor …

thrombin time
Test of the conversion of fibrinogen to fibrin by thrombin in which clotting time of plasma mixed with a thrombin solution is measured. Time is prolonged by afibrinogenaemia, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, heparin. Reptilase, a thrombin-like enzyme unaffected by the prese …

thrombinogen
A coagulation factor needed for the normal clotting of blood. In the cascade of events leading to the final clot, thrombinogen precedes thrombin (and so is a precursor to thrombin). In fact, thrombinogen gives rise to thrombin, and also called prothrombin. ... (12 Dec 1998) ...

thrombinogenesis
Thrombin production. ... (05 Mar 2000) ...

thrombo-
Blood clot; coagulation; thrombin. ... Origin: G. Thrombos, clot (thrombus) ... (05 Mar 2000) ...

thromboangiitis
Inflammation of the intima of a blood vessel, with thrombosis. ... Origin: thrombo-+ G. Angeion, vessel, + -itis, inflammation ... (05 Mar 2000) ...

thromboangiitis obliterans
<disease> A progressive occlusive disease of the blood vessels in the lower extremities. Smoking is considered a major factor in the development and acceleration of this disease. It is autoimmune in nature. ... Synonym:: Buerger's disease. ... (15 Oct 1997) ...

thromboarteritis
Arterial inflammation with thrombus formation. ... (05 Mar 2000) ...

thromboasthenia
Synonym for thrombasthenia ... <haematology> Condition in which there is defective platelet aggregation, though adherence is normal. ... See: Glanzmann's thrombasthenia. ... (18 Nov 1997) ...

thromboblast
Synonym: megakaryocyte. ... Origin: thrombo-+ G. Blastos, germ ... (05 Mar 2000) ...

thromboclastic
Synonym for thrombolytic ... 1. Dissolving or splitting up a thrombus. ... 2. <pharmacology> A thrombolytic agent. ... Origin: Gr. Lysis = dissolution ... (18 Nov 1997) ...

thrombocyst
Thrombocystis ... A membranous sac enclosing a thrombus. ... Origin: thrombo-+ G. Kystis, a bladder ... (05 Mar 2000) ...

thrombocytasthenia
A term for a group of haemorrhagic disorders in which the platelets may be only slightly reduced in number, or even within the normal range, but are morphologically abnormal, or are lacking in factors that are effective in the coagulation of blood. ... Origin: thrombocyte + G. Astheneia, weakness ... (05 Mar 2000) ...

thrombocyte
<haematology> Archaic name for a blood platelet. ... (18 Nov 1997) ...

thrombocythaemia
<haematology> Over-production of platelets. ... See: essential thrombocythaemia. ... (15 Oct 1997) ...

thrombocythemia
Synonym: thrombocytosis. ... Origin: thrombocyte + G. Haima, blood ... (05 Mar 2000) ...

thrombocythemia, haemorrhagic
A clinical syndrome characterised by repeated spontaneous haemorrhages and a remarkable increase in the number of circulating platelets. ... (12 Dec 1998) ...

thrombocytic series
The cells of successive stages in thrombocytic (platelet) development in the bone marrow, e.g., thromboblasts, thrombocytes. ... (05 Mar 2000) ...

thrombocytin
Synonym for serotonin ... 5-hydroxytryptamine ...

thrombocytopathy
General term for any disorder of the coagulating mechanism that results from dysfunction of the blood platelets. ... Origin: thrombocyte + G. Pathos, suffering ... (05 Mar 2000) ...

thrombocytopenia
<haematology> A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting. ... Origin: Gr. Penia = poverty ... (18 Nov 1997) ...

thrombocytopenia purpura
<haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages. ... Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction. ... Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets co …

thrombocytopenic purpura
See: idiopathic thrombocytopenic purpura. ... (05 Mar 2000) ...

thrombocytopoiesis
The process of formation of thrombocytes or platelets. ... Origin: thrombocyte + G. Poiesis, a making ... (05 Mar 2000) ...

thrombocytosis
<haematology> Increased numbers of platelets in the peripheral blood. ... (18 Nov 1997) ...

thromboelastogram
Registration of coagulation process by a thromboelastograph. ... (05 Mar 2000) ...

thromboelastograph
Apparatus for registering elastic variations of a thrombus during the process of coagulation. ... Origin: thromb-+ G. Elastreo, to push, + grapho, to write ... (05 Mar 2000) ...

thromboembolectomy
<procedure> Extraction of an embolic thrombus. ... Origin: thrombo-+ G. Embolos, embolus, + ektome, excision ... (05 Mar 2000) ...

thromboembolic meningoencephalitis
An acute septicaemic disease of cattle caused by the bacterium Haemophilus somnus and characterised by fever, severe depression, ataxia, blindness, coma, and rapid death. ... (05 Mar 2000) ...

thromboembolism
<cardiology> Obstruction of a blood vessel with thrombotic material carried by the blood stream from the site of origin to plug another vessel. ... (18 Nov 1997) ...

thromboendarterectomy
<procedure> An operation that involves opening an artery, removing an occluding thrombus along with the intima and atheromatous material, and leaving a clean, fresh plane internal to the adventitia. ... Origin: thrombo-+ endarterectomy ... (05 Mar 2000) ...

thromboendocarditis
Synonym for nonbacterial thrombotic endocarditis ... Verrucous endocardial lesions occurring in the terminal stages of many chronic infectious and wasting diseases. ... Synonym: abacterial thrombotic endocarditis, cachectic endocarditis, terminal endocarditis, thromboendocarditis. ... (05 Mar 2000) ...

thrombogen
Synonym: prothrombin. ... Origin: thrombo-+ G. -gen, producing ... (05 Mar 2000) ...

thrombogene
Synonym for factor v ... <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease. ... Chemical name: …

thrombogenic
<haematology, pharmacology> Causing thrombosis with clotting or coagulation of the blood. ... Origin: Gr. Gennan = to produce ... (15 Oct 1997) ...

thromboid
Resembling a thrombus. ... Origin: thrombo-+ G. Eidos, resemblance ... (05 Mar 2000) ...

thrombokatilysin
Synonym for factor viii ... A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so f …

thrombokinase
Synonym for thromboplastin ... <haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin). ... (18 Nov 1997) ...

thrombolic
Relating to a thrombolus. ... (05 Mar 2000) ...

thrombolus
An embolus composed of agglutinated platelets. ... Origin: thrombo-+ G. Embolos, embolus ... (05 Mar 2000) ...

thrombolymphangitis
Inflammation of a lymphatic vessel with the formation of a lymph clot. ... (05 Mar 2000) ...

thrombolysis
Fluidifying or dissolving of a thrombus. ... Origin: thrombo-+ G. Lysis, a dissolving ... (05 Mar 2000) ...

thrombolytic
1. Dissolving or splitting up a thrombus. ... 2. <pharmacology> A thrombolytic agent. ... Origin: Gr. Lysis = dissolution ... (18 Nov 1997) ...

thrombolytic agent
Medications that dissolve blot clots (for example streptokinase, tissue plasminogen activator or TPA and urokinase). ... (27 Sep 1997) ...

thrombolytic medication
Medications that dissolve blot clots (for example streptokinase, tissue plasminogen activator or TPA and urokinase). ... (27 Sep 1997) ...

thrombolytic therapy
The use of thrombolytic agents to dissolve blood clots to re-establish blood flow through an occluded vessel. ... Examples of thrombolytic agents include: urokinase, streptokinase and tissue plasminogen activator (TPA). These agents may be introduced into a vein or selectively into a diseased (blocked) artery using a catheter. ... (27 Sep 1997) ...

thrombomodulin
<cell biology> Specific endothelial cell receptor (100 kD: luminal surface only) that forms a 1:1 complex with thrombin. This complex then converts protein C to Ca, that in turn acts on Factors Va and VIIIa. Structurally similar to coated pit receptors. ... (18 Nov 1997) ...

thrombon
An all-inclusive term for circulating thrombocytes (blood platelets) and the cellular forms from which they arise (thromboblasts or megakaryocytes). It is analogous to erythron and leukon of the red and white blood cells, respectively. ... (05 Mar 2000) ...

thrombonecrosis
Necrosis of the walls of a blood vessel, with thrombosis in the lumen. ... (05 Mar 2000) ...

thrombopathic syndrome
<syndrome> A nondescript term to describe any of a number of bleeding diseases in which clot formation is deficient rather than those in which there is an organic fault of the blood vessels. ... (05 Mar 2000) ...

thrombopathy
A non-specific term applied to disorders of blood platelets resulting in defective thromboplastin, without obvious change in the appearance or number of platelets. ... Origin: thrombo-+ G. Pathos, disease ... (05 Mar 2000) ...

thrombopenia
Synonym for thrombocytopenia ... <haematology> A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting. ... Origin: Gr. Penia = poverty ... (18 Nov 1997) ...

thrombopenic purpura
Synonym for idiopathic thrombocytopenic purpura ... idiopathic thrombocytopenia purpura ...

thrombophilia
A disorder of the haemopoietic system in which there is a tendency to the occurrence of thrombosis. ... (12 Dec 1998) ...

thrombophlebitis
<pathology> Inflammation of a vein associated with thrombus formation. ... Origin: Gr. Phleps = vein. ... (18 Nov 1997) ...

thromboplastid
Synonym: platelet. ... 2. A nucleated spindle cell in submammalian blood. ... Origin: thrombo-+ G. Plastos, formed ... (05 Mar 2000) ...

thromboplastin
<haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin). ... (18 Nov 1997) ...

thromboplastinogen
Synonym for factor viii ... A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so f …

thromboplastinogenaemia
The presence of thromboplastinogen in the circulating blood. ... Origin: thromboplastinogen + G. Haima, blood ... (05 Mar 2000) ...

thromboplastinogenase
<enzyme> An enzyme in blood that catalyses the conversion of inactive thromboplastinogen to thromboplastin. ... (05 Mar 2000) ...

thrombopoiesis
Precisely, the process of a clot forming in blood, but generally used with reference to the formation of blood platelets (thrombocytes). ... Origin: thrombo-+ G. Poiesis, a making ... (05 Mar 2000) ...

thrombopoietin
<chemical> A humoral factor that controls blood platelet production through stimulation of megakaryocyte populations. Bone marrow megakaryocytes increase in both size and number in response to exposure to thrombopoietin. ... Chemical name: Thrombopoietin ... (12 Dec 1998) ...

thrombosed
1. Clotted. ... 2. Denoting a blood vessel that is the seat of thrombosis. ... (05 Mar 2000) ...

thromboses
Plural of thrombosis. ... (05 Mar 2000) ...

thrombosin
Synonym for thrombin ... <enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. ... Thrombin is produced from prothrombin by the action either of the extrinsi …

thrombosis
<haematology> The formation, development or presence of a thrombus. ... (14 May 1997) ...

thrombospondin
<cell biology> Homotrimeric glycoprotein (450 kD) from _ granules of platelets and synthesised by various cell types in culture. Also found in extracellular matrix of cultured endothelial, smooth muscle and fibroblastic cells. May have autocrine growth regulatory properties: involved in platelet aggregation. ... (18 Nov 1997) ...

thrombospondin 1
An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumour growth and metas …

thrombospondins
A family of related, adhesive glycoproteins which are synthesised, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of blood coagulation factors and anticoagulant factors. Five distinct forms have bee …

thrombostasis
Local arrest of the circulation by thrombosis. ... Origin: thrombo-+ G. Stasis, a standing ... (05 Mar 2000) ...

thrombosthenin
<cell biology> Obsolete name for platelet contractile protein: now known to be actomyosin (which makes up 15-20% of the total platelet protein). ... (18 Nov 1997) ...

thrombotic
Relating to, caused by, or characterised by thrombosis. ... (05 Mar 2000) ...

thrombotic gangrene
Gangrene due to occlusion of an artery by a thrombus. ... (05 Mar 2000) ...

thrombotic hydrocephalus
Increase in cerebrospinal fluid and of intracranial pressure following thrombosis of the cerebral veins or sinuses; caused by septic infection, dehydration, tuberculosis, typhoid, leukaemia, and other conditions. ... (05 Mar 2000) ...

thrombotic infarct
An infarct caused by a thrombus. ... (05 Mar 2000) ...

thrombotic microangiopathy
Thrombosis within small blood vessels, as in thrombotic thrombocytopenic purpura. ... (05 Mar 2000) ...

thrombotic phlegmasia
Synonym for phlegmasia alba dolens ... An extreme edematous swelling of the leg following childbirth, due to thrombosis of the iliofemoral veins. ... Synonym: leukophlegmasia dolens, milk leg, puerperal phlebitis, thrombotic phlegmasia, white leg. ... (05 Mar 2000) ...

thrombotic thrombocytopenic purpura
A rapidly fatal or occasionally protracted disease with varied symptoms in addition to purpura, including signs of central nervous system involvement, due to formation of fibrin or platelet thrombi in arterioles and capillaries in many organs. ... Synonym: Moschcowitz' disease. ... (05 Mar 2000) ...

thrombotonin
Synonym for serotonin ... 5-hydroxytryptamine ...

thromboxane
<biochemistry> Arachidonic acid metabolites produced by the action of thromboxane synthetase on prostaglandin cyclic endoperoxides. Thromboxane A2 (TxA2) is a potent inducer of platelet aggregation and release and although unstable, the activation of platelets leads to the further production of TxA2. Also causes arteriolar constriction. Anoth …

thromboxane a2
<chemical> An unstable intermediate between the prostaglandin endoperoxides and thromboxane b2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (rcs). ... Chemical name: Thromboxa-5,13-dien-1-oic a …

thromboxane b2
<chemical> A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin). ... Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)- ... (12 Dec 1998) ...

thromboxane dehydrogenase
<enzyme> Converts thromboxane b2 to 11-dehydro-thromboxane b2, but not the reverse reaction; uses nad but not nadp as cofactor; only attacks the 11-hydroxy group of txb2 ... Registry number: EC 1.1.1.- ... Synonym: thromboxane b2 dehydrogenase, 11-hydroxythromboxane b2 dehydrogenase, 11-hydroxy-txb2 dehydrogenase ... (26 Jun 1999) ...

thromboxane-a synthase
<enzyme> An enzyme found predominantly in platelet microsomes. It catalyses the conversion of pgg(2) and pgh(2) (prostaglandin endoperoxides) to thromboxane a2. ... Chemical name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase ... Registry number: EC 5.3.99.5 ... (12 Dec 1998) ...

thromboxanes
Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase. ... (12 Dec 1998) ...

thrombozyme
Synonym for thromboplastin ... <haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin). ... (18 Nov 1997) ...

thrombus
<haematology> An aggregation of blood factors, primarily platelets and fibrin with entrapment of cellular elements, frequently causing vascular obstruction at the point of its formation. Some authorities thus differentiate thrombus formation from simple coagulation or clot formation. ... Compare: embolism. ... Origin: Gr. Thrombos = clot ... (18 …

throstle
1. <zoology> The song thrush. See Song. ... 2. A machine for spinning wool, cotton, etc, from the rove, consisting of a set of drawing rollers with bobbins and flyers, and differing from the mule in having the twisting apparatus stationary and the processes continuous; so called because it makes a singing noise. Throstle cock, the missel thrus …

through
1. From end to end of, or from side to side of; from one surface or limit of, to the opposite; into and out of at the opposite, or at another, point; as, to bore through a piece of timber, or through a board; a ball passes through the side of a ship. ... 2. Between the sides or walls of; within; as, to pass through a door; to go through an avenue. ' …

through drainage
Drainage obtained by the passage of a perforated tube, open at both extremities, through a cavity; in addition, the cavity can be washed out by a solution passed through the tube. ... (05 Mar 2000) ...

through transfer imaging
Synonym for transfer imaging ... The production of an ultrasound image by detection and analysis of sound on the opposite side of the body from the emitting transducer. ... Synonym: through transfer imaging. ... (05 Mar 2000) ...

through-and-through laceration
A laceration that penetrates two surfaces of a structure, generally restricted to skin or mucosal surfaces, such as the cheek, lip, ala nasi, pinna, etc. ... (05 Mar 2000) ...

throw
1. To fling, cast, or hurl with a certain whirling motion of the arm, to throw a ball; distinguished from to toss, or to bowl. ... 2. To fling or cast in any manner; to drive to a distance from the hand or from an engine; to propel; to send; as, to throw stones or dust with the hand; a cannon throws a ball; a fire engine throws a stream of water to …

thrum
1. One of the ends of weaver's threads; hence, any soft, short threads or tufts resembling these. ... 2. Any coarse yarn; an unraveled strand of rope. ... 3. <botany> A threadlike part of a flower; a stamen. ... 4. <chemical> A shove out of place; a small displacement or fault along a seam. ... 5. A mat made of canvas and tufts of yarn. Thr …

thrush
Synonym for candidiasis ... <gastroenterology, microbiology, oncology> Infection with a fungus of the genus Candida. ... It is usually a superficial infection of the moist cutaneous areas of the body and is generally caused by Candida albicans, it most commonly involves the skin (dermatocandidiasis), oral mucous membranes (oral candidiasis), re …

thrush fungus
Synonym for Candida albicans ... <fungus> A dimorphic fungus that is an opportunistic pathogen of humans. A common aetiological agent for candidiasis and thrush. This species is found as a part of the normal gastrointestinal flora. ... (18 Nov 1997) ...

thrust
1. A violent push or driving, as with a pointed weapon moved in the direction of its length, or with the hand or foot, or with any instrument; a stab; a word much used as a term of fencing. '[Polites] Pyrrhus with his lance pursues, And often reaches, and his thrusts renews.' (Dryden) ... 2. An attack; an assault. 'One thrust at your pure, pretended …

thuja
<botany> A genus of evergreen trees, thickly branched, remarkable for the distichous arrangement of their branches, and having scalelike, closely imbricated, or compressed leaves. ... Alternative forms: thuya See Thyine wood. ... Thuja occidentalis is the Arbor vitae of the Eastern and Northern United States. T. Gigantea of North-waetern Americ …