Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine, it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at physiological pH. Spermine is associated with nucleic acids and is thought to stabilize helical stru...
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<biochemistry> Polybasic amine. Found in human sperm, in ribosomes and in some viruses. Involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. ... (18 Nov 1997) ...
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(spur´mēn) a polyamine first found in human semen but now known to occur in almost all tissues, in association with nucleic acids.
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(= N, N' bis(3-aminopropyl)-1,4-butanediamine)) Polybasic amine (polyamine). Found in human sperm, in ribosomes and in some viruses. Involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
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Type: Term Pronunciation: sper′mēn Definitions: 1. A polyamine found in some bacteria; associated with nucleic acids in some viruses; found in human sperm; important in cell and tissue growth; N,N-bis(3-aminopropyl)-1,4-diaminobutane. Synonyms: gerontine, musculamine, neuridine
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