A prodrug is a medication that is administered in an inactive or less than fully active form, and is then converted to its active form through a normal metabolic process, such as hydrolysis of an ester form of the drug. A prodrug is a precursor chemical compound of a drug. Instead of administering a drug, a prodrug might be used instead to improve...
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http://en.wikipedia.org/wiki/Prodrug
Precursor converted to an active form of a
drug within the body. [
2]
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http://sis.nlm.nih.gov/enviro/iupacglossary/glossaryp.html
A prodrug is any compound that undergoes biotransformation before exhibiting its pharmacological effects. Prodrugs can thus be viewed as drugs containing specialized non-toxic protective groups used in a transient manner to alter or to eliminate undesirable properties in the parent molecule . (See also Double prodrug).
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http://www.chem.qmul.ac.uk/iupac/medchem/ix.html
A chemical structure that undergoes conversion to an active drug within a biological system, such conversion usually involving metabolism.
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http://www.combichemistry.com/glossary_p.html
A chemical structure that undergoes conversion to an active drug within a biological system, such conversion usually involving metabolism.
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http://www.combichemistry.com/medical-chemistry-glossary.html
A compound that is converted within the body into its active form that has medical effects. Prodrugs useful when the active drug may be too toxic to administer ter systemically, the active drug is absorbed poorly by the digestive tract, or the body breaks down the active drug before it reaches its target. ... (09 Oct 1997) ...
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http://www.encyclo.co.uk/local/20973
(pro´drәg) a compound that, on administration, must undergo chemical conversion by metabolic processes before becoming an active pharmacological agent; a precursor of a drug.
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http://www.encyclo.co.uk/local/21001
a compound that is converted to an active drug within the body.
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http://www.encyclo.co.uk/local/22225
Type: Term Pronunciation: prō′drŭg Definitions: 1. A class of drugs, the pharmacologic action of which results from conversion by metabolic processes within the body (biotransformation).
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http://www.medilexicon.com/medicaldictionary.php?t=72541
Prodrug: A precursor (forerunner) of a drug. A prodrug must undergo chemical conversion by metabolic processes before becoming an active pharmacological agent. For example, sulfasalazine is a prodrug. It is not active in its ingested form. It has to be broken down by bacteria in the colon into two products -- 5-aminosalicylic acid (5ASA) and sulfap...
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http://www.medterms.com/script/main/art.asp?articlekey=23992
A chemical precursor of a drug that is converted into the desired substance in the body.
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http://www.virology.net/ATVGlossary.html
an inactive substance that is converted to a drug within the body by the action of enzymes or other chemicals.
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https://www.infoplease.com/dictionary/prodrug
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