The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Macrolides belong to the polyketide class of natural p...
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http://en.wikipedia.org/wiki/Macrolide
(from the article `drug`) The macrolides (e.g., erythromycin, clarithromycin, azithromycin) are usually administered orally, but they can be given parenterally. These drugs, ...
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http://www.britannica.com/eb/a-z/m/6
<pharmacology> A group of antibiotics produced by various strains of Streptomyces that have a complex macrocyclic structure. ... They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria. ... (18 Nov 1997) ....
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http://www.encyclo.co.uk/local/20973
(mak´ro-līd) a chemical compound characterized by a large lactone ring containing multiple keto and hydroxyl groups. any of a group of antibacterial antibiotics containing such a ring linked to one or more sugars.
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http://www.encyclo.co.uk/local/21001
Type: Term Pronunciation: mak′rō-līd Definitions: 1. A natural lactone with a large ring; usually consisting of 14-20 atoms; macrolides include a class of antibiotics discovered in streptomycetes, erythromycin; macrolides also inhibit protein biosynthesis.
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http://www.medilexicon.com/medicaldictionary.php?t=52176
Macrolide: One in a class of antibiotics that includes Biaxin, Clarithromycin, Ery-Tab, and Erythromycin. The macrolides inhibit the growth of bacteria and are often prescribed to treat rather common bacterial infections. In more technical terms, the macrolides are a group of antibiotics produced by various strains of Streptomyces (spore forming ba...
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http://www.medterms.com/script/main/art.asp?articlekey=11422
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