Thioxanthene is a chemical compound in which the oxygen atom in xanthene is replaced with a sulfur atom. It is also related to phenothiazine. Several of its derivatives are used as typical antipsychotics in the treatment of schizophrenia and other psychoses. == Derivatives == The derivatives of thioxanthene used clinically as antipsychotics includ...
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<pharmacology> A group of medications with antipsychotic activity which act by blocking postsynaptic dopamine receptors in the brain. ... Examples include: thiothixene, chlorprothixene and flupenthixol. ... (27 Sep 1997) ...
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(thi″o-zan´thēn) a three-ring compound structurally related to phenothiazine. any of a class of structurally related antipsychotic agents, including thiothixene.
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Type: Term Pronunciation: thī′ō-zan′thēn Definitions: 1. A class of tricyclic compounds resembling phenothiazine, but with the central ring nitrogen replaced by a carbon atom; current use emphasizes the antipsychotic and antiemetic properties of this class.
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Thioxanthene: One of a group of drugs with antipsychotic activity which act by blocking postsynaptic (after-the-nerve) receptors for dopamine (a chemical that nerves use to communicate with one another) in the brain. Examples include: thiothixene (brand name: Navane), chlorprothixene (Remeron) and flupenthixol.
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