Tetanus toxin is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, or TeNT. The LD50 of this toxin has been measured to be approximate...
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http://en.wikipedia.org/wiki/Tetanospasmin
(from the article `tetanus`) Both the occurrence and severity of tetanus are determined by the amount of toxin produced and the resistance of the host. The neurotoxic component, ...
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<protein> See tetanus toxin. ... (18 Nov 1997) ...
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(tet″ә-no-spaz´min) the neurotoxic component of the tetanus toxin, which causes the muscle spasms of tetanus.
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See tetanus toxin.
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Type: Term Pronunciation: tet′ă-nō-spaz′min Definitions: 1. The neurotoxin of Clostridium tetani, which causes the characteristic signs and symptoms of tetanus; chief action is on the anterior horn cells, and the spasms seem to be due to action at inhibitory synapses.
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tetanospasmin The neurotoxic component of the exotoxin (tetanus toxin) produced by Clostridium tetani, a highly potent protein that binds to gangliosides and blocks the synaptic terminals of the central nervous system, causing the typical muscle spasms of tetanus. It is one of the most powerful poisons known.
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