==Clinical use== Tacrine was the prototypical cholinesterase inhibitor for the treatment of Alzheimer`s disease. William K. Summers received a patent for this use (US Patent No. 4,816,456). Studies found that it may have a small beneficial effect on cognition and other clinical measures, though study data was limited and the clinical relevance of....
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http://en.wikipedia.org/wiki/Tacrine
<chemical> A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of alzheimer's disease and other central nervous system disorders. ... Pharmacological action: cholinesterase inhibitor, nootropic agents, parasympathomi...
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http://www.encyclo.co.uk/local/20973
(tak´rēn) a cholinesterase inhibitor used to improve cognitive performance in treatment of dementia of the Alzheimer type; used as the hydrochloride salt.
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http://www.encyclo.co.uk/local/21001
Type: Term Pronunciation: tak′rēn Definitions: 1. An anticholinesterase agent with nonspecific CNS stimulatory effects; used in early stages of Alzheimer disease.
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http://www.medilexicon.com/medicaldictionary.php?t=89543
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