Retinoblastoma definitions

Retinoblastoma

1) Malignant neoplasm 2) Malignant tumor 3) Metastatic tumor
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Retinoblastoma (Rb) is a rapidly developing cancer that develops from the immature cells of a retina, the light-detecting tissue of the eye and is the most common malignant tumor of the eye in children . ==Frequency of retinoblastoma== Retinoblastoma presents with cumulative lifetime incidence rate of 18000 to 30000 live births worldwide. A higher...
Found on http://en.wikipedia.org/wiki/Retinoblastoma

retinoblastoma

(from the article `tumour suppressor gene`) Cancer research has led to the identification and characterization of many tumour suppressor genes. In 1971 Alfred Knudson, Jr., postulated that a ... Retinoblastoma, an aggressive tumour of the eye that typically occurs in childhood, offers perhaps one of the clearest examples of the interpla...
Found on http://www.britannica.com/eb/a-z/r/39

retinoblastoma

Cancer that forms in the tissues of the retina (the light-sensitive layers of nerve tissue at the back of the eye). Retinoblastoma usually occurs in children younger than 5 years. It may be hereditary or nonhereditary (sporadic).
Found on http://www.cancer.gov/dictionary?expand=R

retinoblastoma

<oncology, tumour> Malignant tumour of the retina, usually arising in the inner nuclear layer of the neural retina. ... Retinoblastoma is unusual in being caused by an autosomal dominant mutation in some cases (about 6%), in which case it may be bilateral. ... The gene product of the retinoblastoma gene is a tumour suppressor that interacts w...
Found on http://www.encyclo.co.uk/local/20973

retinoblastoma

(ret″ĭ-no-blas-to´mә) a malignant congenital hereditary blastoma composed of retinal cells arising from the nuclear layers, appearing in one or both eyes in children under 5 years of age; it is usually first diagnosed because of the presence of a bright white or yellow pupillary reflex (leukokoria).
Found on http://www.encyclo.co.uk/local/21001

Retinoblastoma

A rare childhood cancer of the eye.
Found on http://www.encyclo.co.uk/local/21474

Retinoblastoma

A childhood malignant cancer of the retina of the eye. Reverse transcriptase viral enzyme used to ma
Found on http://www.encyclo.co.uk/local/22391

retinoblastoma

Malignant tumour of the retina, usually arising in the inner nuclear layer of the neural retina. Retinoblastoma is unusual in being caused by an autosomal dominant mutation in some cases (about 6%), in which case it may be bilateral. The gene product of the retinoblastoma gene is a tumour suppressor that interacts with transcription factors such as E2F to block transcription of growth-regulating genes. The Rb gene plays a role in normal development, not just that of the retina. ...
Found on http://www.encyclo.co.uk/visitor-contributions.php

retinoblastoma

Type: Term Pronunciation: ret′i-nō-blas-tō′mă Definitions: 1. Malignant ocular neoplasm of childhood, with onset usually before the third year of life, composed of primitive retinal small round cells with deeply staining nuclei and elongated cells forming rosettes; the risk of developing osteosarcoma increases later in li...
Found on http://www.medilexicon.com/medicaldictionary.php?t=77943

Retinoblastoma

Our Retinoblastoma Main Article provides a comprehensive look at the who, what, when and how of Retinoblastoma Retinoblastoma: A malignant eye tumor in children, usually under age 5, that arises in cells in the developing retina containing cancer-predisposing mutations in both copies of the gene RB1. The most common sign of retinoblastoma (RB) is a...
Found on http://www.medterms.com/script/main/art.asp?articlekey=5341