Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a `core protein` with one or more covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a Ser residue to which the glycosaminoglycan is joined through a tetrasaccharide bridge (e.g. chondroitin sulfate-GlcA-Gal-Gal-Xyl-PRO.....
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http://en.wikipedia.org/wiki/Proteoglycan
A molecule that contains both protein and glycosaminoglycans, which are a type of polysaccharide. Proteoglycans are found in cartilage and other connective tissues.
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http://www.cancer.gov/dictionary?expand=P
<protein> A high molecular weight complex of protein and polysaccharide, characteristic of structural tissues of vertebrates, such as bone and cartilage, but also present on cell surfaces. Important in determining viscoelastic properties of joints and other structures subject to mechanical deformation. Glycosaminoglycans (GAGs), the polysacch...
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http://www.encyclo.co.uk/local/20973
(pro″te-o-gli´kan) any of a group of glycoproteins found primarily in connective tissue and formed of subunits of glycosaminoglycans (long polysaccharide chains containing amino sugars) linked to a protein core like bristles on a bottle brush. Hydrated proteoglycans form the highly viscous fluid of mucus and...
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http://www.encyclo.co.uk/local/21001
A high molecular weight complex of protein and polysaccharide, characteristic of structural tissues of vertebrates, such as bone and cartilage, but also present on cell surfaces. Important in determining viscoelastic properties of joints and other structures subject to mechanical deformation. Glycosaminoglycans (GAGs), the polysaccharide units in proteoglycans, are polymers of acidic disaccharides containing derivatives of the amino sugars glucosamine or galactosamine.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: prō′tē-ō-glī′kan Definitions: 1. A glycoaminoglycans (mucopolysaccharides) bound to protein chains in covalent complexes; occur in the extracellular matrix of connective tissue.
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http://www.medilexicon.com/medicaldictionary.php?t=73078
a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue.
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https://www.infoplease.com/dictionary/proteoglycan
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