Properdin or Factor P is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases. It is found in the blood serum of more complex animals. ==Structure== Properdin is a gamma globulin protein composed of multiple identical protein subunits with a separate ligand-binding site. Native properdin oc...
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http://en.wikipedia.org/wiki/Properdin
<protein> Component of the alternative pathway for complement activation: complexes with C3b and stabilises the alternative pathway C3 convertase (C3bBbP) that cleaves C3. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
(pro´pәr-din) a protein of the alternative complement pathway, augmenting complement activation. Called also factor P.
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http://www.encyclo.co.uk/local/21001
(= Factor P) Component of the alternative pathway for complement activation: complexes with C3b and stabilizes the alternative pathway C3 convertase (C3bBbP) that cleaves C3.
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Type: Term Pronunciation: prō′per-din Definitions: 1. A control protein for the alternate complement cascade, properdin stabilizes the C
3 convertase enzyme, a deficiency of which increases susceptibility to systemic meningococcal infections and can be inherited in an x-linked pattern.
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No exact match found.
