(= Factor P) Component of the alternative pathway for complement activation: complexes with C3b and stabilizes the alternative pathway C3 convertase (C3bBbP) that cleaves C3.
Properdin or Factor P is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases. It is found in the blood serum of more complex animals. ==Structure== Properdin is a gamma globulin protein composed of multiple identical protein subunits with a separate ligand-binding site. Native properdin oc...Found on http://en.wikipedia.org/wiki/Properdin
(pro´pәr-din) a protein of the alternative complement pathway, augmenting complement activation. Called also factor P.Found on http://www.encyclo.co.uk/local/21001
<protein> Component of the alternative pathway for complement activation: complexes with C3b and stabilises the alternative pathway C3 convertase (C3bBbP) that cleaves C3. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
properdin (prō'purdun) , protein found in the blood serum of humans and some of the higher animals that appears to participate in certain specific immune responses. It is associated with the engulfing of foreign particles and invading cells by phagocytes and with tissue inflammation (see b...Found on http://www.infoplease.com/ce6/sci/A0840269.html
Type: Term Pronunciation: prō′per-din Definitions: 1. A control protein for the alternate complement cascade, properdin stabilizes the C3
convertase enzyme, a deficiency of which increases susceptibility to systemic meningococcal infections and can be inherited in an x-linked pattern.Found on http://www.medilexicon.com/medicaldictionary.php?t=72775
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