Panosteitis, sometimes shortened to pano among breeders, is an occasionally seen long bone condition in large breed dogs. It manifests with sudden, otherwise unexplained pain and lameness sometimes shifting from leg to leg, usually between 5 and 14 months of age. Signs such as fever and weight loss, and symptoms such as anorexia, and lethargy can ... Found on http://en.wikipedia.org/wiki/Panosteitis