In medicine, refers to something that occurs in the normal or usual place in the body. It is often used to describe tissue or an organ that is transplanted into its normal place in the body.
In the normal or usual position. ... Origin: ortho-+ G. Topos, place ... (05 Mar 2000) ... 
(or″tho-top´ik) occurring at the normal place in the body. pertaining to a tissue transplant grafted into its normal place in the body.
Type: Term Pronunciation: ōr′thō-top′ik Definitions: 1. In the normal or usual position.
orthotopic 1. A reference to a tissue graft to a site on the body where that tissue would normally be present. 2. Describing a tissue transplant that is grafted into its normal anatomical position. 3. Occurring in the normal, or usual, place; not heterotopic nor ectopic.