Microtubule blocker - binds to tubulin heterodimer rendering it assembly-incompetent.
<chemical> (5-(2-thienylcarbonyl) 1h-benzimidazol-2-yl)carbamic acid methyl ester. Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules. ... Pharmacological action: antineoplastic agent. ... Chemical name: Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester ... (12 Dec 1998) ... Found on http://www.encyclo.co.uk/local/20973
Nocodazole is an anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. Microtubules are one type of fibre which constitutes the cytoskeleton, and the dynamic microtubule network has several important roles in the cell, including vesicular transport, forming the mitotic spindle and in cytokin...Found on http://en.wikipedia.org/wiki/Nocodazole
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