Mitotane, also known as o,p`-DDD (Lysodren), is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It is an isomer of DDD and is a derivative of DDT. Its main use is in those patients who have persistent disease despite surgical resection, those who are not surgical candidates, or those who have metastatic disease. It....
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http://en.wikipedia.org/wiki/Mitotane
(from the article `drug`) ...forms of leukemia, require this amino acid for growth and development. Other agents, such as dacarbazine and procarbazine, act through various ...
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http://www.britannica.com/eb/a-z/m/102
An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing disease).
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http://www.cancer.gov/dictionary?expand=M
<chemical> 1-chloro-2-(2,2-dichloro)-1-(4-chlorophenyl)ethylbenzene. A derivative of the insecticide ddd that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumours and causes CNS damage, but no bone marrow depression. ... Pharmacological action: antineoplastic agent, hor...
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http://www.encyclo.co.uk/local/20973
(mi´to-tān) a cytotoxic compound that causes severe damage to the adrenal cortex; administered orally as an antineoplastic agent for palliative treatment of inoperable adrenocortical carcinoma.
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http://www.encyclo.co.uk/local/21001
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