Synonym: agyria. ... Origin: G. Lissos, smooth, + enkephalos, brain ... (05 Mar 2000) ... 
Type: Term Pronunciation: lis′en-sĕ-fā′lē-ă Synonyms: agyria
lissencephalia, lissencephalic, lissencephaly 1. Lack of convolutional patterns in the cerebral cortex due to some defect of development; also known as agyria [a-, 'no' plus gyros, 'circle']. 2. A rare brain formation disorder characterized by microcephaly and the lack of normal convolutions (folds) in the brain. It is caused by defective neuronal...