The active ingredient in a drug used to lessen the toxic effects of substances that block the action of folic acid, especially the anticancer drug methotrexate. Leucovorin is used to treat some types of anemia and is also used with fluorouracil to treat colorectal cancer. It is also being studied in the treatment of other types of cancer and other ...
Found on
http://www.cancer.gov/dictionary?expand=L
<chemical> The active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. ... Pharmacological action: antidotes. ... Chemical name: L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methy...
Found on
http://www.encyclo.co.uk/local/20973
(loo″ko-vo´rin) folinic acid. leucovorin calcium the calcium salt of folinic acid, used as an antidote for folic acid antagonists (such as methotrexate) when there is need to reverse the toxic effects of the latter, in the treatment of megaloblastic anemias due to folic acid deficie...
Found on
http://www.encyclo.co.uk/local/21001
Type: Term Pronunciation: lū′kō-vōr′in Synonyms: folinic acid
Found on
http://www.medilexicon.com/medicaldictionary.php?t=48978
Leucovorin: Folinic acid, the active form of folic acid in the body. Used as an antidote to protect normal cells from high doses of the anticancer drug methotrexate and to increase the antitumor effects of fluorouracil (5-FU) and tegafur-uracil. Also used to prevent or treat anemia due to folic acid deficiency. Also known as citrovorum factor and W...
Found on
http://www.medterms.com/script/main/art.asp?articlekey=32998
A form of the B vitamin, folate that is preferentially taken up by human cells. Leucovorin thereby protects from the effect of folate-antagonist antibiotics.
Found on
http://www.virology.net/ATVGlossary.html
No exact match found.
