The fifth base of nucleic acids. Important because it fails to form specific pair bonds with the other bases. In transfer RNAs, this property is used in the anticodon to allow matching of a single tRNA to several codons. PCR perfomed with primers containing inosine tolerates a limited degree of mismatch between primer and template, useful in homolo...
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(I) (in´o-sēn) a purine nucleoside containing the base hypoxanthine and the sugar ribose, which occurs in transfer RNAs. inosine monophosphate(IMP) a nucleotide produced by removal of the amine group from adenosine monophosphate in metabolism ...
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http://www.encyclo.co.uk/local/21001
The 'fifth base' of nucleic acids. Important because it fails to form specific pair bonds with the other bases. In transfer RNAs, this property is used in the anticodon to allow matching of a single tRNA to several codons. PCR performed with primers containing inosine tolerates a limited degree of mismatch between primer and template, useful when trying to clone homologous protein by using degenerate primers.
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(I, Ino) Type: Term Pronunciation: in′ō-sēn Definitions: 1. a nucleoside formed by the deamination of adenosine. Synonyms: hypoxanthinosine
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