1) Symptom 
<haematology> A condition or group of conditions where the haemolytic activity (red blood cell destruction) of the spleen is increased. The spleen is often enlarged. ... (11 Jan 1998) ... 
(hi″pәr-splen´iz-әm) a condition characterized by excessive breakdown of red blood cells by the spleen, so that the levels of red cells and other blood elements drop; there are too many blood cells in the bone marrow and the spleen is often enlarged.
Type: Term Pronunciation: hī′pĕr-splēn′izm Definitions: 1. Any of a group of conditions in which the cellular components of the blood or platelets are removed at an abnormally high rate by the spleen, resulting in low circulating levels.
[n] - enlarged spleen and a decrease in one or more types of blood cells
an abnormal condition characterized by an enlarged spleen that prematurely destroys red blood cells or platelets. Also called