==Mechanism of action== Ganciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) gene UL97 during infection. Subsequently, cellular kinases catalyze the formation of ganciclovir diphosphate and ganciclovir triphosphate, which is prese...
Found on
http://en.wikipedia.org/wiki/Ganciclovir
An antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body's immune system is suppressed. In gene therapy, ganciclovir is used with an altered herpes simplex virus-1 gene to kill advanced melanoma cells and brain tumor cells.
Found on
http://www.cancer.gov/dictionary?expand=G
<drug> Antiviral nucleoside analogue: 9 (1,3 dihydroxy 2 propoxymethyl guanine. Used in treatment of cytomegalovirus. ... (18 Nov 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
(gan-si´klo-vir) a derivative of acyclovir used in the form of the base or the sodium salt in treatment of cytomegalovirus infections of the retina; administered orally, intravenously, or by intravitreous injection or implantation.
Found on
http://www.encyclo.co.uk/local/21001
Antiviral nucleoside analogue: 9-((1,3-dihydroxy-2-propoxy)methyl)-guanine. Used in treatment of cytomegalovirus.
Found on
http://www.encyclo.co.uk/visitor-contributions.php
An antiviral drug FDA-approved to treat cytomegalovirus (CMV) retinitis and to prevent CMV disease in transplant patients at risk for CMV. It has also been used to treat CMV colitis, CMV esophagitis, AIDS-related meningoencephalitis and AIDS-related polyradiculopathy; generally administered intravenously. An oral form of the drug is under study for...
Found on
http://www.virology.net/ATVGlossary.html
No exact match found.
