(= tetrahydrofolate) Molecule that acts as a carrier of one-carbon units in intermediary metabolism. It contains residues of p -aminobenzoate, glutamate, and a substituted pteridine. The latter cannot be synthesized by mammals, which must obtain tetrahydrofolate as a vitamin or from intestinal microorganisms. One-carbon units are carried at three different levels of oxidation, as methyl-, methylene- or formimino- groups. Important biosyntheses dependent on tetrahydrofolate include those of methionine, thymine and purines. Analogues of dihydrofolate, such as aminopterin and methotrexate block the action of tetrahydrofolate by inhibiting its regeneration from dihydrofolate.
<biochemistry> Molecule that acts as a carrier of one carbon units in intermediary metabolism. It contains residues of p aminobenzoate, glutamate and a substituted pteridine. The latter cannot be synthesised by mammals, which must obtain tetrahydrofolate as a vitamin or from intestinal microorganisms. One carbon units are carried at three dif...Found on http://www.encyclo.co.uk/local/20973
(fo´lāt) the anionic form of folic acid.Found on http://www.encyclo.co.uk/local/21001
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Folate helps to make red blood cells. It is found in whole-grain breads and cereals, liver, green vegetables, orange juice, lentils, beans, and yeast. Folate is water-soluble (can dissolve in water) and must be taken in every day. Not enough folat...Found on http://www.cancer.gov/dictionary?expand=F
B vitamin that is necessary for cell growth and division. Folate is found in leafy green veg, beans and grains. The folate in prenatal vitamin supplements occurs in only one form, which is folic acid. Consuming adequate amounts of folate and folic acid prevent neural tube defects of the fetus during pregnancy. Narrower term(s): Folic AcidFound on http://www.pregnology.com/Pregnancy-dictionary/
Folate: Folic acid, one of the B vitamins that is a key factor in the synthesis (the making) of nucleic acid (DNA and RNA). A deficiency of folic acid after birth causes a kind of anemia, namely, megaloblastic anemia in which there is a paucity of red blood cells and those that are made are unusually large and immature (so-called blast cells). Lack...Found on http://www.medterms.com/script/main/art.asp?articlekey=3494
Type: Term Pronunciation: fō′lāt Definitions: 1. A salt or ester of folic acid.Found on http://www.medilexicon.com/medicaldictionary.php?t=34237
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