1) Abnormal condition 2) Abnormalcy 3) Abnormality 4) Excessive irritability 5) Occupational disease 6) Physical irritability 
Erethism or erethism mercurialis is a neurological disorder which affects the whole central nervous system, as well as a symptom complex derived from mercury poisoning. This is also sometimes known as the mad hatter disease. Historically, this was common among old England felt-hatmakers who used mercury to stabilize the wool in a process called fe...
abnormal irritability
• (n.) A morbid degree of excitement or irritation in an organ.
Er'e·thism noun [ Greek ... irritation, from ... to stir, rouse, from ... to stir: confer French éréthisme .] (Medicine) A morbid degree of excitement or irritation in an organ. Hoblyn. 
Type: Term Pronunciation: er′ē-thizm Definitions: 1. Neuropsychiatric symptom of chronic mercury poisoning marked by irritability, emotional instability, depression, and fatigue.
[n] - an abnormally high degree of irritability or sensitivity or excitability
noun an abnormally high degree of irritability or sensitivity to stimulation of an organ or body part
an unusual or excessive degree of irritability or stimulation in an organ or tissue.