1) Antigout agent
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https://www.crosswordclues.com/clue/colchicine
Adverse effects are primarily gastrointestinal upset at high doses. In addition to gout, colchicine is used to treat familial Mediterranean fever, pericarditis, and Behçet`s disease. ==Medical uses== ===Gout=== Colchicine is an alternative for those unable to tolerate NSAIDs in gout. At high doses side effects (primarily gastrointestinal upset) ....
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http://en.wikipedia.org/wiki/Colchicine
• (n.) A powerful vegetable alkaloid, C17H19NO5, extracted from the Colchicum autumnale, or meadow saffron, as a white or yellowish amorphous powder, with a harsh, bitter taste; -- called also colchicia.
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http://thinkexist.com/dictionary/meaning/colchicine/
drug used in the treatment of gout, a disease that is characterized by severe inflammation in one or more of the joints of the extremities. ... [1 related articles]
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http://www.britannica.com/eb/a-z/c/107
A drug used to treat gout (inflamed joints caused by a buildup of uric acid). It comes from the crocus plant Colchicum autumnale. Colchicine blocks cell division and the movement of certain immune cells to areas that are inflamed. It is a type of alkaloid and a type of mitotic inhibitor.
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http://www.cancer.gov/dictionary?expand=C
<drug> Alkaloid (400 D) isolated from the Autumn crocus (Colchicum autumnale) that blocks microtubule assembly by binding to the tubulin heterodimer (but not to tubulin). ... As a result of interfering with microtubule reassembly will block mitosis at metaphase. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
(kol´chĭ-sēn) an alkaloid from Colchicum autumnale (meadow saffron), used in treatment of gout, including for termination of an attack of acute gout. Side effects include gastrointestinal symptoms and hypotension.
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http://www.encyclo.co.uk/local/21001
A poisonous yellow crystalline alkaloid C22H25NO6 extracted from the meadow saffron (Colchicum autumnale) that induces polyploidy when applied to mitotic cells.
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Col'chi·cine noun [ Confer French
colchicine .]
(Chemistry) A powerful vegetable alkaloid, C
17 H
19 NO
5 , extracted from the
Colchicum autumnale , or meadow saffron, as a white or yellowish amorphous powder, with a harsh, bitter taste; -- called al...
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http://www.encyclo.co.uk/webster/C/107
Type: Term Pronunciation: kol′chi-sin Definitions: 1. An alkaloid obtained from Colchicum autumnale (family Liliaceae); used in the chronic treatment of gout. Inhibits microtuble formation.
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http://www.medilexicon.com/medicaldictionary.php?t=18799
Our Colchicine Main Article provides a comprehensive look at the who, what, when and how of Colchicine Colchicine: A substance found in a plant that is used in clinical medicine for the treatment of gouty arthritis and in the laboratory to arrest cells during cell division (by disrupting the spindle) so their chromosomes can be visualized. The name...
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http://www.medterms.com/script/main/art.asp?articlekey=2775
Colchicine is an alkaloid derived from meadow saffron.
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http://www.probertencyclopaedia.com/browse/GC.HTM
a pale yellow, crystalline alkaloid, CHNO, the active principle of colchicum.
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https://www.infoplease.com/dictionary/colchicine
No exact match found.
