ADF/cofilin is a family of actin-binding proteins which disassembles actin filaments. Three highly conserved and highly (70%-82%) identical genes belonging to this family have been described in humans and mice: Actin-binding proteins regulate assembly and disassembly of actin filaments. Cofilin, a member of the ADF/cofilin family is actually a pro...
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<cell biology> Actin severing protein (19 kD), related to destrin. Binds to the side of filaments and is pH sensitive. ... Shares with tropomyosin a 13 amino acid F actin binding domain. Very similar to actin depolymerising factor. ... (18 Nov 1997) ...
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