Originally introduced in 1959 for the treatment of hypertension. Its use as an antiarrhythmic for ventricular fibrilation was discovered and patented by Marvin Bacaner in 1969 at the University of Minnesota. The American Heart Association removed Bretylium from their 2000 ECC/ACC guidelines due to its unproven efficacy and ongoing supply problems....
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http://en.wikipedia.org/wiki/Bretylium
<drug> An antihypertensive which on chronic oral dosing diminishes the release of norepinephrine from noradrenergic nerve endings. ... Pharmacologic action: Suppress ventricular fibrillation and ventricular tachycardia, initially releases norepinephrine, then prevents synaptic release of norepinephrine; transiently increases myocardial contra...
Found on
http://www.encyclo.co.uk/local/20973
(brә-til´e-әm) an adrenergic blocking agent used in the form of the tosylate salt to control arrhythmias in certain cases of ventricular tachycardia or fibrillation; administered by intravenous or intramuscular injection.
Found on
http://www.encyclo.co.uk/local/21001
Type: Term Pronunciation: bre-til′ē-ŭm Definitions: 1. An antiarrhythmic used to treat life-threatening ventricular arrhythmias. Initially releases norepinephrine, then blocks its reuptake, thus depressing excitability of sympathetic nerve terminals.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=12314
A drug which diminishes the release of norepinephrine from nerve endings with chronic oral dosing. It is used in treatment of ventricular fibrillation and ventricular tachycardia.
Found on
https://www.encyclo.co.uk/local/22445
a substance, CHBrNOS, used to treat acute ventricular arrhythmias and suppress ventricular fibrillation.
Found on
https://www.infoplease.com/dictionary/bretylium
No exact match found.
