(from the article `drug`) Hydroxyurea inhibits the enzyme ribonucleotide reductase, an important element in DNA synthesis. It is used to reduce the high granulocyte count ... Found on http://www.britannica.com/eb/a-z/a/113
A drug that is used to treat acute lymphoblastic leukemia (ALL) and is being studied in the treatment of some other types of cancer. It is an enzyme taken from the bacterium Escherichia coli (E. coli). It breaks down the amino acid asparagine and may block the growth of tumor cells that need asparagine to grow. Also called Elspar and L-asparaginase... Found on http://www.cancer.gov/dictionary?expand=A
<drug, enzyme> An enzyme that hydrolyses L asparagine to L aspartate and ammonia that is used as an antitumour agent especially against lymphosarcoma and lymphatic leukaemia. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
(as-par´ә-jin-ās″) an enzyme that catalyzes removal of the amine group that results in breakdown of asparagine; used as an antineoplastic agent against cancers such as acute lymphoblastic leukemia in which the malignant cells require exogenous asparagine for protein synthesis. Found on http://www.encyclo.co.uk/local/21001
Enzyme (EC 3.5.1.1) that hydrolyzes L-asparagine to L-aspartate and ammonia that is used as an anti-tumour agent especially against lymphosarcoma and lymphatic leukaemia.
Found on http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: as-par′ă-ji-nās Definitions: 1. An enzyme catalyzing the hydrolysis of l-asparagine to l-aspartate and ammonia. 2. The enzyme from Escherichia coli, used in the treatment of acute leukemia and other neoplastic diseases. Found on http://www.medilexicon.com/medicaldictionary.php?t=7903