Argatroban is given intravenously and drug plasma concentrations reach steady state in 1-3 hours. Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibito...
Found on
http://en.wikipedia.org/wiki/Argatroban
(ahr-gat´ro-ban″) an anticoagulant that binds to the thrombin active site and inhibits various thrombin-catalyzed reactions; used in the prophylaxis and treatment of thrombocytopenia resulting from treatment with heparin, administered intravenously.
Found on
http://www.encyclo.co.uk/local/21001
No exact match found.
