Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement components C3, C4 and C5 are large glycoproteins that have important functions in the immune response and host defense. They have a wide variety of biological activities and are proteolytically a...
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http://en.wikipedia.org/wiki/Anaphylatoxin
<protein> Originally used as an antigen that reacted with an IgE antibody thus precipitating reactions of anaphylaxis. ... Now restricted to defining a property of complement fragments C3a and C5a, both of which bind to the surfaces of mast cells and basophils and cause the release of inflammatory mediators. ... (18 Nov 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
(an″ә-fil´ә-tok″sin) a substance produced by complement activation that causes the release of histamine and other mediators of immediate hypersensitivity from basophils and mast cells, thereby producing signs and symptoms of immediate hypersensitivity (anaphylaxis) without involvement of immunoglobulin...
Found on
http://www.encyclo.co.uk/local/21001
Substance capable of releasing histamine from mast cells.
Found on
http://www.encyclo.co.uk/local/21016
Originally used of an antigen that reacted with an IgE antibody thus precipitating reactions of anaphylaxis. Now restricted to defining a property of complement fragments C3a and C5a, both of which bind to the surfaces of mast cells and basophils and cause the release of inflammatory mediators.
Found on
http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: an′ă-fil-ă-tok′sin Definitions: 1. Low molecular weight cleavage products (C3a, C4a, and C5a); generated by the activation of the complement cascade. They are proinflammatory; can cause permeability, smooth muscle contraction, and mask cell degranulation. Synonyms: anaphylotoxin
Found on
http://www.medilexicon.com/medicaldictionary.php?t=3383
A substance (e.g., C3a, C4a, or C5a) capable of directly triggering mast cell degranulation.
Found on
http://www.roitt.com/glossary.asp
No exact match found.
