Aminoglutethimide is an anti-steroid drug marketed under the tradename Cytadren by Novartis around the world. It blocks the production of steroids derived from cholesterol and is clinically used in the treatment of Cushing`s syndrome and metastatic breast cancer. It is also used by body builders. ==Mechanism== Aminoglutethimide has two mechanisms....
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http://en.wikipedia.org/wiki/Aminoglutethimide
An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.
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http://www.cancer.gov/dictionary?expand=A
<chemical> An aromatase inhibitor that produces a state of 'medical' adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to oestrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. ... P...
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http://www.encyclo.co.uk/local/20973
(ә-me″no-gloo-teth´ĭ-mīd) an antihormone that inhibits conversion of cholesterol to pregnenolone, thus reducing adrenocortical steroid synthesis; administered orally in treatment of Cushing syndrome. It also inhibits conversion of androstenedione to estrone in peripheral tissues and is sometimes us...
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http://www.encyclo.co.uk/local/21001
a hormone antagonist, CHNO, used in the treatment of Cushing's syndrome and breast cancer.
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https://www.infoplease.com/dictionary/aminoglutethimide
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