A form of tissue plasminogen activator that is made in the laboratory. It helps dissolve blood clots and is used to treat heart attacks, strokes, and clots in the lungs. It is also being studied in the treatment of cancer. It is a type of systemic thrombolytic agent. Also called Activase, r-tPA, and recombinant tissue plasminogen activator.
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<drug> A thrombolytic agent which works by activating the bodys own fibrinolytic system by activating the production of plasmin from plasminogen. Plasmin is an enzyme which degrades fibrin clots and fibrinogen, as well as several other protein clotting factors. ... (27 Sep 1997) ...
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http://www.encyclo.co.uk/local/20973
(al´tә-plās) a tissue plasminogen activator produced by recombinant DNA technology; used in therapy for acute myocardial infarction, acute ischemic stroke, and acute pulmonary embolism, administered intravenously.
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Type: Term Pronunciation: awl-tĕ-plāz Definitions: 1. A tissue plasminogen activator made by recombinant DNA technology, used as a thrombolytic.
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http://www.medilexicon.com/medicaldictionary.php?t=2500
Our Alteplase Main Article provides a comprehensive look at the who, what, when and how of Alteplase Alteplase: Generic name of a tissue plasminogen activator produced by recombinant DNA technology. The brand name is Activase. See: Tissue plasminogen activator.
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