Ceredase is the trade name of a citrate buffered solution of alglucerase that was manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher`s disease. This was the first drug appoved as an enzyme replacement therapy. It was approved by the FDA in 1991. It has been withdrawn from ....
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http://en.wikipedia.org/wiki/Alglucerase
<enzyme> Modified form of human placental glucocerebrosidase; oligosaccharide units of glucocerebrosidase are sequentially deglycosylated to yield a mannose-terminated preparation which is targeted to the mannose lectin on the macrophage plasma membrane ... Registry number: EC 3.2.1.- ... Synonym: ceredase ... (26 Jun 1999) ...
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http://www.encyclo.co.uk/local/20973
(al-gloo´sәr-ās″) a modified form of the enzyme lacking in Gaucher disease, used in treatment of the adult form of the disease.
Found on
http://www.encyclo.co.uk/local/21001
No exact match found.
