1) Blood disease 2) Blood disorder 
<haematology> A rare condition where the majority of red blood cells are acanthocytes (red blood cells with multiple spiny cytoplasmic projections), a feature of abetalipoproteinaemia. ... (27 Sep 1997) ... 
(ә-kan″tho-si-to´sis) the presence in the blood of acanthocytes.
Condition in which red cells of the blood show spiky deformation; symptomatic of abetalipoproteinaemia.
Type: Term Pronunciation: ă-kan′thō-sī-tō′sis Definitions: 1. A rare condition in which the most of erythrocytes are acanthocytes; a regular feature of abetalipoproteinemia; also sometimes present in severe hepatocellular disease.
[n] - the presence of acanthocytes in the blood stream (as in abetalipoproteinemia)
noun the presence of acanthocytes in the blood stream (as in abetalipoproteinemia)
a condition characterized by large numbers of acanthocytes in the blood.