Topotecan

After GlaxoSmithKline received final FDA approval for Hycamtin Capsules on October 15, 2007, topotecan is the first topoisomerase I inhibitor for oral use. ==Indications (approved uses)== ==Experimental use== ==Mode of action== Hycamtin or topotecan is a semi-synthetic derivative of camptothecin. Camptothecin is a natural product extracted from th...
Found on http://en.wikipedia.org/wiki/Topotecan

topotecan

<drug, oncology> This alkaloid chemotherapy drug is a derivative of the drug camptothecin, which was originally isolated from a Chinese tree, Camptotheca acuminata but has also been found in the nothapodytes tree (Nothapodytes foetida).Topotecan is a DNA topoisomerase I inhibitor and is used to treat advanced ovarian cancer. ... (09 Oct 1997)...
Found on http://www.encyclo.co.uk/local/20973

topotecan

(to″po-te┬┤kan) an antineoplastic agent used as the hydrochloride salt in treatment of metastatic ovarian carcinoma and small cell lung carcinoma; administered by intravenous infusion.
Found on http://www.encyclo.co.uk/local/21001

topotecan

A drug used to treat certain types of ovarian cancer, lung cancer, and cervical cancer. Topotecan is a type of topoisomerase inhibitor. Also called Hycamtin and topotecan hydrochloride.
Found on http://www.cancer.gov/dictionary?expand=T
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