Papillon–Lefèvre syndrome (PLS), also known as palmoplantar keratoderma with periodontitis, is an autosomal recessive genetic disorder caused by a deficiency in cathepsin C. ==Characteristics== PLS is characterized by periodontitis and palmoplantar keratoderma. The severe destruction of periodontium results in loss of most primary teeth by the ...
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http://en.wikipedia.org/wiki/Papillon–Lefèvre_syndrome
<syndrome> A rare congenital hyperkeratosis of the palms and soles (palmoplantar keratoderma), with progessive destruction of the alveolar bone of both the deciduous and permanent teeth. ... It occurs between the first and fifth years of life and has autosomal recessive inheritance. ... Inheritance: autosomal recessive. ... (05 Mar 2000) ......
Found on
http://www.encyclo.co.uk/local/20973
(pah″pe-yaw´ lә-fev´rә) an autosomal recessive disorder occurring between the first and fifth years of life, characterized by psoriasiform palmoplantar keratoderma, which may also involve the elbows, knees, tibias, external malleoli, and other areas; ectopic calcifications of the skull; and perio...
Found on
http://www.encyclo.co.uk/local/21001
Type: Term Pronunciation: pah-pē-on[h]′ le-fĕv Definitions: 1. a congenital hyperkeratosis of the palms and soles, with progessive destruction of alveolar bone about the deciduous and permanent teeth beginning as early as 2 years of age, and also with premature exfoliation of teeth and calcification of the falx cerebri; autosomal re...
Found on
http://www.medilexicon.com/medicaldictionary.php?t=88660
Papillon-Lefèvre syndrome, inherited as an autosomal recessive trait, is characterized by an erythematous palmoplantar keratoderma, and a periodontosis associated with the loss of teeth early in life. The keratoderma is apparent before age 6 and extends up the sides of the feet.
Found on
http://www.skincareguide.ca/glossary/p/papillon_lefevre_syndrome.html
No exact match found.
