Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene. Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crys...
Found on
http://en.wikipedia.org/wiki/Osteonectin
a bone glycoprotein which has the property of binding to both collagen fibres and the hydroxyapatite crystals, and thus may be important in initiating bone mineralisation by acting as a template for nucleation. Osteonectin is also produced by endothelial cells and plateletes and is able to bindfibrinogen.
Found on
http://www.encyclo.co.uk/local/20169
<protein> Calcium binding protein of bone, containing the EF hand motif. Binds to both collagen and hydroxyapatite. ... (18 Nov 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
(= basement membrane protein BM-40; SPARC) Calcium-binding protein of bone, containing the EF-hand motif. Binds to both collagen and hydroxyapatite.
Found on
http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: os′tē-ō-nek′tin Definitions: 1. A protein (MW 39,000-40,000) found in bone and nonmineralized tissues and believed to play a role in mineralization.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=63825
No exact match found.
