HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). HBeAg is the extracellular form of HBcAg, hence why the presence of both are markers of viral replication, and antib... Found on http://en.wikipedia.org/wiki/HBcAg